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Sensitivity to Change

2012-12-06 Science
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Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 588/5 ( reviews)

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Book Synopsis Sensitivity to Change by : Emin Özsoy

Download or read book Sensitivity to Change written by Emin Özsoy. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Recent decades have seen a degradation of the environmental quality in semi-enclosed seas, which are particularly sensitive to population pressures due to their naturally low flushing rates related to their geometry. The North Sea, Baltic Sea and the Black Sea are amongst the most seriously threatened seas in the Euro-Asian region. Each semi-enclosed sea has a distinct pattern of circulation, transport, mixing, associated with the particular geometry, topography, boundary processes, interior stratification, atmospheric forcing, ice fonnation, straits / sill controls, and the specific inputs of freshwater, nutrients and pollutants. The workshop investigated the distinctive physical and ecological characteristics of the three seas in a comparative manner, in order to identify the types of driving forces and dynamic controls operating on productivity, nutrient cycling, physical transport and mixing mechanisms. A comparative study of these controlling mechanisms would allow us to better understand ecosystem sensitivity in these different environments. The workshop presentations highlighted the complexity of the semi-enclosed seas related to the interaction amongst the physical, chemical and biological fields, and differences in time and space scales in each of the systems. Further, a strong climate signal exists in these systems, manifest in the interannual, interdecadal and longer term variability. Part of the variability appears connected with background climatic variability.

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

2013-02-21 Medical
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Release : 2013-02-21
Genre : Medical
Kind : eBook
Book Rating : 236/5 ( reviews)

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Book Synopsis Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide by : Agency for Health Care Research and Quality (U.S.)

Download or read book Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide written by Agency for Health Care Research and Quality (U.S.). This book was released on 2013-02-21. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

The Prevention and Treatment of Missing Data in Clinical Trials

2010-12-21 Medical
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Release : 2010-12-21
Genre : Medical
Kind : eBook
Book Rating : 51X/5 ( reviews)

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Book Synopsis The Prevention and Treatment of Missing Data in Clinical Trials by : National Research Council

Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council. This book was released on 2010-12-21. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.

Sensitivity Training

1972 Control (Psychology)
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Release : 1972
Genre : Control (Psychology)
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Sensitivity Training by : Michael Robert Cline

Download or read book Sensitivity Training written by Michael Robert Cline. This book was released on 1972. Available in PDF, EPUB and Kindle. Book excerpt:

Motor Control

2023-04-05 Medical
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Release : 2023-04-05
Genre : Medical
Kind : eBook
Book Rating : 667/5 ( reviews)

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Book Synopsis Motor Control by : Anne Shumway-Cook

Download or read book Motor Control written by Anne Shumway-Cook. This book was released on 2023-04-05. Available in PDF, EPUB and Kindle. Book excerpt: Motor Control: Translating Research into Clinical Practice, 6th Edition, is the only text that bridges the gap between current and emerging motor control research and its application to clinical practice. Written by leading experts in the field, this classic resource prepares users to effectively assess, evaluate, and treat clients with problems related to postural control, mobility, and upper extremity function using today’s evidence-based best practices. This extensively revised 6th Edition reflects the latest advances in research and features updated images, clinical features, and case studies to ensure a confident transition to practice. Each chapter follows a consistent, straightforward format to simplify studying and reinforce understanding of normal control process issues, age-related issues, research on abnormal function, clinical applications of current research, and evidence to support treatments used in the rehabilitation of patients with motor control problems.

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