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Regulation of the Endocytic Adaptor Protein Eps15 by the CtBP Family of Metabolic Sensors

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Release : 2016
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Kind : eBook
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Book Synopsis Regulation of the Endocytic Adaptor Protein Eps15 by the CtBP Family of Metabolic Sensors by : Abbie Mead

Download or read book Regulation of the Endocytic Adaptor Protein Eps15 by the CtBP Family of Metabolic Sensors written by Abbie Mead. This book was released on 2016. Available in PDF, EPUB and Kindle. Book excerpt:

Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems

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Release : 2012-09-26
Genre : Science
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Book Rating : 695/5 ( reviews)

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Book Synopsis Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems by : Marc Thiriet

Download or read book Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems written by Marc Thiriet. This book was released on 2012-09-26. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors. Activation of signaling effectors triggers the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Complex stages of cell signaling can be studied using proper mathematical models, once the role of each component is carefully handled. Volume 4 also reviews various categories of cytosolic and/or nuclear mediators and illustrates some major signal transduction pathways, such as NFkappaB axis, oxygen sensing, and mechanotransduction.

Trafficking Inside Cells

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Release : 2010-05-30
Genre : Science
Kind : eBook
Book Rating : 77X/5 ( reviews)

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Book Synopsis Trafficking Inside Cells by : Nava Segev

Download or read book Trafficking Inside Cells written by Nava Segev. This book was released on 2010-05-30. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

Oxford Textbook of Cancer Biology

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Release : 2019-05-02
Genre : Medical
Kind : eBook
Book Rating : 453/5 ( reviews)

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Book Synopsis Oxford Textbook of Cancer Biology by : Francesco Pezzella

Download or read book Oxford Textbook of Cancer Biology written by Francesco Pezzella. This book was released on 2019-05-02. Available in PDF, EPUB and Kindle. Book excerpt: The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.

Membrane Recycling

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Release : 1982
Genre : Science
Kind : eBook
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Book Synopsis Membrane Recycling by : Geralyn M. Collins

Download or read book Membrane Recycling written by Geralyn M. Collins. This book was released on 1982. Available in PDF, EPUB and Kindle. Book excerpt:

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