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Proteomics and Protein-Protein Interactions

2006-12-22 Medical
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Release : 2006-12-22
Genre : Medical
Kind : eBook
Book Rating : 324/5 ( reviews)

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Book Synopsis Proteomics and Protein-Protein Interactions by : Gabriel Waksman

Download or read book Proteomics and Protein-Protein Interactions written by Gabriel Waksman. This book was released on 2006-12-22. Available in PDF, EPUB and Kindle. Book excerpt: Gabriel Waksman Institute of Structural Molecular Biology, Birkbeck and University College London, Malet Street, London WC1E 7HX, United Kingdom Address for correspondence: Professor Gabriel Waksman Institute of Structural Molecular Biology Birkbeck and University College London Malet Street London WC1E 7H United Kingdom Email: g. waksman@bbk. ac. uk and g. waksman@ucl. ac. uk Phone: (+44) (0) 207 631 6833 Fax: (+44) (0) 207 631 6833 URL: http://people. cryst. bbk. ac. uk/?ubcg54a Gabriel Waksman is Professor of Structural Molecular Biology at the Institute of Structural Molecular Biology at UCL/Birkbeck, of which he is also the director. Before joining the faculty of UCL and Birkbeck, he was the Roy and Diana Vagelos Professor of Biochemistry and Molecular Biophysics at the Washington University School of Medicine in St Louis (USA). The rapidly evolving ?eld of protein science has now come to realize the ubiquity and importance of protein–protein interactions. It had been known for some time that proteins may interact with each other to form functional complexes, but it was thought to be the property of only a handful of key proteins. However, with the advent of hi- throughput proteomics to monitor protein–protein interactions at an organism level, we can now safely state that protein–protein interactions are the norm and not the exception.

Protein-Protein Interactions

2023-07-14 Science
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Release : 2023-07-14
Genre : Science
Kind : eBook
Book Rating : 279/5 ( reviews)

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Book Synopsis Protein-Protein Interactions by : Shahid Mukhtar

Download or read book Protein-Protein Interactions written by Shahid Mukhtar. This book was released on 2023-07-14. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume provides a comprehensive collection of classic and cutting-edge methods and techniques in mapping protein-protein interactions. The chapters include a variety of in vitro and in vivo experimental methods covering cell biology, biochemistry, and biophysics. In addition, the book also explores in silico methods including sequence-, structure-, and phylogenetic profile-based approaches as well as gene expression and machine learning methods. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Protein-Protein Interactions: Methods and Protocols serves as an ideal guide for researchers working in protein science and beyond.

Proteomics

2007-05-08 Science
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Release : 2007-05-08
Genre : Science
Kind : eBook
Book Rating : 956/5 ( reviews)

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Book Synopsis Proteomics by : Timothy Palzkill

Download or read book Proteomics written by Timothy Palzkill. This book was released on 2007-05-08. Available in PDF, EPUB and Kindle. Book excerpt: Proteomics is an introduction to the exciting new field of proteomics, an interdisciplinary science that includes biology, bioinformatics, and protein chemistry. The purpose of this book is to provide the active researcher with an overview of the types of questions being addressed in proteomics studies and the technologies used to address those questions. Key subjects covered in this book include: an assessment of the limitations of this approach and outlines new developments in mass spectrometry that will advance future research high-throughput recombinant DNA cloning methods used to systematically clone all of the open reading frames of an organism into plasmid vectors for large scale protein expression and functional studies such as protein-protein interactions with the two-hybrid system protein structure an overview of large-scale experimental attempts to determine the three-dimensional structures of representative sets of proteins computational approaches to determining the three-dimensional structure of proteins. Proteomics provides a starting point for researchers who would like a theoretical understanding of the new technologies in the field, and obtain a solid grasp of the fundamentals before integrating new tools into their experiments. Written with attention to detail, but without being overwhelmingly technical, Proteomics is a user-friendly guide needed by most biologists today.

What Mad Pursuit

2008-08-06 Science
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Release : 2008-08-06
Genre : Science
Kind : eBook
Book Rating : 842/5 ( reviews)

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Book Synopsis What Mad Pursuit by : Francis Crick

Download or read book What Mad Pursuit written by Francis Crick. This book was released on 2008-08-06. Available in PDF, EPUB and Kindle. Book excerpt: Candid, provocative, and disarming, this is the widely-praised memoir of the co-discoverer of the double helix of DNA.

Protein-Protein Interactions

2021-05-19 Science
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Release : 2021-05-19
Genre : Science
Kind : eBook
Book Rating : 942/5 ( reviews)

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Book Synopsis Protein-Protein Interactions by : Krishna Mohan Poluri

Download or read book Protein-Protein Interactions written by Krishna Mohan Poluri. This book was released on 2021-05-19. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the fundamental aspects of protein-protein interactions (PPI), including a detailed account of the energetics and thermodynamics involved in these interactions. It also discusses a number of computational and experimental approaches for the prediction of PPI interactions and reviews their principles, advantages, drawbacks, and the recent developments. Further, it offers structural and mechanistic insights into the formation of protein-protein complexes and maps different PPIs into networks to delineate various pathways that operate at the cellular level. Lastly, it describes computational protein-protein docking techniques and discusses their implications for further experimental research. Given its scope, this book is a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.

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