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Protein-based Engineered Nanostructures

2016-09-27 Science
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Release : 2016-09-27
Genre : Science
Kind : eBook
Book Rating : 968/5 ( reviews)

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Book Synopsis Protein-based Engineered Nanostructures by : Aitziber L. Cortajarena

Download or read book Protein-based Engineered Nanostructures written by Aitziber L. Cortajarena. This book was released on 2016-09-27. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the engineering of protein-based nanostructures and nanomaterials. One key challenge in nanobiotechnology is to be able to exploit the natural repertoire of protein structures and functions to build materials with defined properties at the nanoscale using “bottom-up” strategies. This book addresses in an integrated manner all the critical aspects that need to be understood and considered to design the next generation of nano-bio assemblies. The book covers first the fundamentals of the design and features of the protein building blocks and their self-assembly illustrating some of the most relevant examples of nanostructural design. Finally, the book contains a section dedicated to demonstrated applications of these novel bioinspired nanostructures in different fields from hybrid nanomaterials to regenerative medicine. This book provides a comprehensive updated review of this rapidly evolving field.

Self-assembled Protein-based Nanoarchitectures

2014
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Release : 2014
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Book Synopsis Self-assembled Protein-based Nanoarchitectures by : Andreas Schreiber

Download or read book Self-assembled Protein-based Nanoarchitectures written by Andreas Schreiber. This book was released on 2014. Available in PDF, EPUB and Kindle. Book excerpt:

Protein-based Nanoarchitectures

2010
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Release : 2010
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Book Synopsis Protein-based Nanoarchitectures by : Leonardo Maestri Teixeira

Download or read book Protein-based Nanoarchitectures written by Leonardo Maestri Teixeira. This book was released on 2010. Available in PDF, EPUB and Kindle. Book excerpt: The ability to efficiently build and control structures at the nanometer scale using biomolecules is currently an area of very active research. Although natural systems have a vast repertoire of nanostructures able to self-assemble into complex systems, its adoption in industrial nanofabrication process is still a utopian idea. Crystalline bacterial cell surface layer (S-layer) proteins are an example of biological, self-assembled nanostructures that can be exploited for nanotechnology applications. This dissertation focuses on the self-formation of Lysinibacillus sphaericus S-layer (SbpA) and the exploitation of its intrinsic properties for nanobiofabrication. SbpA self-assembly kinetics were studied in detail, as well as, the interaction of SbpA with synthetic surfaces mimicking the natural substrate used as an anchor by SbpA on the bacterial cell surface. It was found that SbpA self-assembles in solution at a rate that is dependent on temperature, the concentration of SbpA, as well as the concentration of calcium ions, and sodium chloride. In addition, SbpA-carbohydrate interaction is dependent on the carbohydrate density, and the net dissociation rate slows with increasing association times. Surface-enhanced Raman spectroscopy (SERS) substrates were bionanofabricated with the aid of a recombinant SbpA, where sub-micromolar concentration levels of 2-mercaptopyridine could be detected, demonstrating the potential of the bionanofabricated SERS substrate using recombinant SbpA.

Design and Synthesis of Novel, Functional Polymer-protein Nanoarchitectures

2008
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Release : 2008
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Book Synopsis Design and Synthesis of Novel, Functional Polymer-protein Nanoarchitectures by : Benjamin Le Droumaguet

Download or read book Design and Synthesis of Novel, Functional Polymer-protein Nanoarchitectures written by Benjamin Le Droumaguet. This book was released on 2008. Available in PDF, EPUB and Kindle. Book excerpt: The work undertaken during this Ph.D. consisted in the development of the synthesis but also in the characterization of a recently discovered subclass of amphiphilic biohybrid macromolecules called "Giant Amphiphiles". In this manuscript, three new synthetic routes allowed for the first time the efficient, high yielding, and easy synthesis of these "Giant Amphiphiles" biomacromolecules without tedious purification procedures.

Nano- and Microfabrication for Industrial and Biomedical Applications

2016-06-12 Technology & Engineering
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Release : 2016-06-12
Genre : Technology & Engineering
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Book Rating : 287/5 ( reviews)

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Book Synopsis Nano- and Microfabrication for Industrial and Biomedical Applications by : Regina Luttge

Download or read book Nano- and Microfabrication for Industrial and Biomedical Applications written by Regina Luttge. This book was released on 2016-06-12. Available in PDF, EPUB and Kindle. Book excerpt: Nano- and Microfabrication for Industrial and Biomedical Applications, Second Edition, focuses on the industrial perspective on micro- and nanofabrication methods, including large-scale manufacturing, the transfer of concepts from lab to factory, process tolerance, yield, robustness, and cost. The book gives a history of miniaturization and micro- and nanofabrication, and surveys industrial fields of application, illustrating fabrication processes of relevant micro and nano devices. In this second edition, a new focus area is nanoengineering as an important driver for the rise of novel applications by integrating bio-nanofabrication into microsystems. In addition, new material covers lithographic mould fabrication for soft-lithography, nanolithography techniques, corner lithography, advances in nanosensing, and the developing field of advanced functional materials. Luttge also explores the view that micro- and nanofabrication will be the key driver for a "tech-revolution" in biology and medical research that includes a new case study that covers the developing organ-on-chip concept. Presents an interdisciplinary approach that makes micro/nanofabrication accessible equally to engineers and those with a life science background, both in academic settings and commercial R&D Provides readers with guidelines for assessing the commercial potential of any new technology based on micro/nanofabrication, thus reducing the investment risk Updated edition presents nanoengineering as an important driver for the rise of novel applications by integrating bio-nanofabrication into microsystems

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