1# Library to Find Best eBook for Read
Author : Burcin Ekser
Release : 2022-10-11
Genre : Medical
Kind : eBook
Book Rating : 121/5 ( reviews)
Book Synopsis Progress of Allo- and Xeno-Transplantation Facilitating the Initial Xeno-Kidney and Islet Clinical Trials by : Burcin Ekser
Download or read book Progress of Allo- and Xeno-Transplantation Facilitating the Initial Xeno-Kidney and Islet Clinical Trials written by Burcin Ekser. This book was released on 2022-10-11. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lisha Mou
Release : 2024-06-21
Genre : Medical
Kind : eBook
Book Rating : 657/5 ( reviews)
Book Synopsis Community series in Progress of Allo- and Xeno-transplantation Facilitating the Initial Xeno-Kidney and Islet Clinical Trials, volume II by : Lisha Mou
Download or read book Community series in Progress of Allo- and Xeno-transplantation Facilitating the Initial Xeno-Kidney and Islet Clinical Trials, volume II written by Lisha Mou . This book was released on 2024-06-21. Available in PDF, EPUB and Kindle. Book excerpt: Owing to the availability of more advanced genetically engineered pigs, more immunological and physiological barriers have been overcome. With the results of pig organ xenotransplantation steadily improving, consideration is now given to the first clinical trials of xenotransplantation. The first step is kidneys, but possibilities also exist in pig islet transplantation for patients with diabetes.
Author : David K. C. Cooper
Release : 2020-09-08
Genre : Medical
Kind : eBook
Book Rating : 277/5 ( reviews)
Book Synopsis Clinical Xenotransplantation by : David K. C. Cooper
Download or read book Clinical Xenotransplantation written by David K. C. Cooper. This book was released on 2020-09-08. Available in PDF, EPUB and Kindle. Book excerpt: This title provides an illuminating examination of the current state of xenotransplantation – grafting or transplanting organs or tissues between members of different species – and how it might move forward into the clinic. To be sure, this is a critical topic, as a major problem that remains worldwide is an inadequate supply of organs from deceased human donors, severely limiting the number of organ transplants that can be performed each year. Based on presentations given at a major conference on xenotransplantation, this title includes important views from many leading experts who were invited to present their data and opinions on how xenotransplantation can advance into the clinic. Attention was concentrated on pig kidney and heart transplantation as it is in regard to these organs that most progress has been made. Collectively, these chapters effectively highlight the many advantages of xenotransplantation to patients with end-stage organ failure, thereby encouraging the mapping of a concrete pathway to clinical xenotransplantation. The book is organized across 22 chapters, beginning with background information on clinical and experimental xenotransplantation. Following this are discussions addressing how pigs can be genetically engineered for their organs to be resistant to the human immune response through deletion of pig xenoantigens, and the insertion of ‘protective’ human transgenes. Subsequent chapters analyze complications that arise in practice, comparing allotransplant and xenotransplant rejection. The selection of the ideal patients for the first clinical trials is discussed. Finally, the book concludes with an analysis on the regulatory, economic, and social aspects of this research, including FDA perspectives and the sensitive, psychosocial factors regarding allotransplantation and xenotransplantation. A major and timely addition to the literature, Clinical Xenotransplantation will be of great interest to all researchers, physicians, and academics from other disciplines with an interest in xenotransplantation.
Author : Shuji Miyagawa
Release : 2020-03-11
Genre : Technology & Engineering
Kind : eBook
Book Rating : 639/5 ( reviews)
Book Synopsis Xenotransplantation by : Shuji Miyagawa
Download or read book Xenotransplantation written by Shuji Miyagawa. This book was released on 2020-03-11. Available in PDF, EPUB and Kindle. Book excerpt: Recently, remarkable progress has been made in the area of preclinical xenotransplantation experiments. Surprisingly, a heterotopic heart from the gene-editing pig continued to beat for almost 2.5 years, when implanted in the monkey abdomen, and a pig life-supporting kidney could also function for over 1.3 years in monkeys. Concerning islets, islets from gene-editing pigs could work for more than one year in monkeys. It is noteworthy that one group reported a survival of adult wild-type pig islets of over 600 days. On the other hand, the progress in these preclinical trials strongly affected not only the xenotransplantation study itself but regeneration studies to use pigs as a scaffold to foster human induced pluripotent stem cells.
Author : Institute of Medicine
Release : 1996-07-12
Genre : Medical
Kind : eBook
Book Rating : 267/5 ( reviews)
Book Synopsis Xenotransplantation by : Institute of Medicine
Download or read book Xenotransplantation written by Institute of Medicine. This book was released on 1996-07-12. Available in PDF, EPUB and Kindle. Book excerpt: Xenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed. This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.
