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Precision Molecular Pathology of Uterine Cancer

2017-10-28 Medical
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Release : 2017-10-28
Genre : Medical
Kind : eBook
Book Rating : 851/5 ( reviews)

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Book Synopsis Precision Molecular Pathology of Uterine Cancer by : Michael T. Deavers

Download or read book Precision Molecular Pathology of Uterine Cancer written by Michael T. Deavers. This book was released on 2017-10-28. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive review for practicing pathologists to understand the molecular biology, diagnostics, and predictive markers and implications for therapy of uterine cancer. While molecular based therapeutic strategies for uterine cancer are not as well developed as for some other organ sites, these are the most common gynecologic malignancies and there have been many important recent developments that are discussed in this volume. Comprehensive chapters address essential information about endometrial carcinoma, uterine mesenchymal tumors, and cervical carcinoma and include the pathogenesis of carcinoma and discuss molecular based classification, biomarkers, therapy, prevention, and hereditary cancers of the uterus. Precision Molecular Pathology of Uterine Cancer is a unique and one of a kind resource for practicing pathologists, pathologists in training and gynecologists.

Molecular Pathology of Gynecologic Cancer

2007-10-05 Medical
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Release : 2007-10-05
Genre : Medical
Kind : eBook
Book Rating : 463/5 ( reviews)

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Book Synopsis Molecular Pathology of Gynecologic Cancer by : Antonio Giordano

Download or read book Molecular Pathology of Gynecologic Cancer written by Antonio Giordano. This book was released on 2007-10-05. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. It approaches research into the pathology and treatment of gynecologic oncology from both clinical and experimental perspectives. New insights made possible by the introduction of advanced technologies into the field are presented. This new volume will be necessary reading for clinicians and experimental researchers alike.

Uterine Cancer

2009-06-10 Medical
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Release : 2009-06-10
Genre : Medical
Kind : eBook
Book Rating : 442/5 ( reviews)

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Book Synopsis Uterine Cancer by : Franco Muggia

Download or read book Uterine Cancer written by Franco Muggia. This book was released on 2009-06-10. Available in PDF, EPUB and Kindle. Book excerpt: For the Editors, the task of writing a Preface is most satisfying. It represents the completion of the book and a moment of reflection on whether the whole is more than the sum of all the parts. And also, one must reflect on how this book is likely to be utilized in this era of rapid communications. The Editors first met in May 2003 at a stimulating Italian symposium on endometrial cancer (organizers Drs. Luigi Frigerio, Roberto Grassi and Andrea Lissoni, with participation of the deans of Italian Gynecologic Oncology, Ugo Bianchi and Constantino Mangioni) that took place at Bergamo and Caravaggio. The impressive gains in biology and clinical trials were further discussed by the two editors and others that are co-authors in this venture on this side of the Atlantic at a 2004 Educational Session at the American Society of Clinical Oncology (ASCO). The pace of progress in various aspects of management of uterine cancer was no- worthy, not only was tumor biology fueling novel hypotheses such as questioning the mesenchymal origin of carcinosarcomas, but knowledge of molecular pathways was beginning to be applied as prognostic and as predictive factors portending benefit from systemic therapies. Surgical staging and sensitive imaging provided the underpinning for refining our treatment algorithms. Finally, a role for che- therapy had finally become established, principally through phase III studies c- paring chemotherapy to radiation in mostly locally advanced stages III and IV that had undergone resection.

Molecular Pathology of Breast Cancer

2016-11-26 Medical
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Release : 2016-11-26
Genre : Medical
Kind : eBook
Book Rating : 614/5 ( reviews)

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Book Synopsis Molecular Pathology of Breast Cancer by : Sunil Badve

Download or read book Molecular Pathology of Breast Cancer written by Sunil Badve. This book was released on 2016-11-26. Available in PDF, EPUB and Kindle. Book excerpt: The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. The application of next generation sequencing (NGS) has provided new insights in the regulation of genomic and transcriptomic structure and function. Alterations in DNA such as mutations and single nucleotide polymorphisms (SNPs) have been correlated with outcomes and provide for novel therapeutic approaches. These NGS analyses have also revealed the extensive contributions of epigenetic mechanisms such as histone modifications, non-coding RNA and alternative splicing. All of these changes together contribute to alterations in proteome. Newer assays that allow greater stability and analytical consistency are emerging. These alterations in tumor profiles can be also now detected by imaging techniques. The heterogeneity of both tumor and tumor microenvironment, an inevitable reality, is discussed in detail with particular focus on cancer stem cells and immune signaling. A chapter is dedicated to the emerging technology of “liquid biopsy”, which opens a novel approach for “continuous” monitoring of cancer that might be superior to conventional diagnostics, “Molecular Pathology of Breast Cancer” provides a quick and easy, not to mention essential, tour for clinicians, pathologists and scientists who are seeking to understand the integration of molecular biology into the diagnosis, prognosis and management of breast cancer.

Female Genital Tumours: Who Classification of Tumours

2020-09-30 Medical
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Release : 2020-09-30
Genre : Medical
Kind : eBook
Book Rating : 049/5 ( reviews)

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Book Synopsis Female Genital Tumours: Who Classification of Tumours by : W. H. O. Classification WHO Classification of Tumours Editorial Board

Download or read book Female Genital Tumours: Who Classification of Tumours written by W. H. O. Classification WHO Classification of Tumours Editorial Board. This book was released on 2020-09-30. Available in PDF, EPUB and Kindle. Book excerpt: ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Female Genital Tumours is the fourth volume in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. What's new in this edition? The 5th edition, guided by the WHO Classification of Tumours Editorial Board, will establish a single coherent cancer classification presented across a collection of individual volumes organized on the basis of anatomical site (digestive system, breast, soft tissue and bone, etc.) and structured in a systematic manner, with each tumour type listed within a taxonomic classification: site, category, family (class), type, and subtype. In each volume, the entities are now listed from benign to malignant and are described under an updated set of headings, including histopathology, diagnostic molecular pathology, staging, and easy-to-read essential and desirable diagnostic criteria. Who should read this book? - Pathologists - Oncologists - Cancer researchers - Surgeons - Epidemiologists - Cancer registrars This volume - Prepared by 191 authors and editors - Contributors from around the world - More than 850 high-quality images - More than 3100 references

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