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Personalized Computational Hemodynamics

2020-04-19 Science
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Release : 2020-04-19
Genre : Science
Kind : eBook
Book Rating : 546/5 ( reviews)

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Book Synopsis Personalized Computational Hemodynamics by : Yuri Vassilevski

Download or read book Personalized Computational Hemodynamics written by Yuri Vassilevski. This book was released on 2020-04-19. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences. Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies. Examines a variety of medical disciplines targeted by mathematical modeling and computer simulation Discusses how the results of numerical simulations are used to support clinical decision-making Covers hemodynamics relating to various subject areas, including vascular surgery and oncological tumor treatments

Patient-specific Hemodynamic Computations: Application to Personalized Diagnosis of Cardiovascular Pathologies

2017-05-31 Medical
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Release : 2017-05-31
Genre : Medical
Kind : eBook
Book Rating : 531/5 ( reviews)

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Book Synopsis Patient-specific Hemodynamic Computations: Application to Personalized Diagnosis of Cardiovascular Pathologies by : Lucian Mihai Itu

Download or read book Patient-specific Hemodynamic Computations: Application to Personalized Diagnosis of Cardiovascular Pathologies written by Lucian Mihai Itu. This book was released on 2017-05-31. Available in PDF, EPUB and Kindle. Book excerpt: Hemodynamic computations represent a state-of-the-art approach for patient-specific assessment of cardiovascular pathologies. The book presents the development of reduced-order multiscale hemodynamic models for coronary artery disease, aortic coarctation and whole body circulation, which can be applied in routine clinical settings for personalized diagnosis. Specific parameter estimation frameworks are introduced for calibrating the parameters of the models and high performance computing solutions are employed to reduce their execution time. The personalized computational models are validated against patient-specific measurements. The book is written for scientists in the field of biomedical engineering focusing on the cardiovascular system, as well as for research-oriented physicians in cardiology and industrial players in the field of healthcare technologies.

Patient-Specific Modeling of the Cardiovascular System

2010-09-03 Science
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Release : 2010-09-03
Genre : Science
Kind : eBook
Book Rating : 919/5 ( reviews)

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Book Synopsis Patient-Specific Modeling of the Cardiovascular System by : Roy C.P. Kerckhoffs

Download or read book Patient-Specific Modeling of the Cardiovascular System written by Roy C.P. Kerckhoffs. This book was released on 2010-09-03. Available in PDF, EPUB and Kindle. Book excerpt: Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial pressure and flow distributions. Thrombus formation is identified as a potentially important contributor to changed material properties of the arterial wall. Understanding how the wall adapts and remodels its material properties in the face of changes in both the stress loading and blood constituents associated with infl- matory processes (IL6, CRP, MMPs, etc.

Image-based Computational Approaches for Personalized Cardiovascular Medicine: Improving Clinical Applicability and Reliability through Medical Imaging and Experimental Data

2023-07-13 Science
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Release : 2023-07-13
Genre : Science
Kind : eBook
Book Rating : 577/5 ( reviews)

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Book Synopsis Image-based Computational Approaches for Personalized Cardiovascular Medicine: Improving Clinical Applicability and Reliability through Medical Imaging and Experimental Data by : Selene Pirola

Download or read book Image-based Computational Approaches for Personalized Cardiovascular Medicine: Improving Clinical Applicability and Reliability through Medical Imaging and Experimental Data written by Selene Pirola. This book was released on 2023-07-13. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Hemodynamics – Theory, Modelling and Applications

2015-02-24 Technology & Engineering
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Release : 2015-02-24
Genre : Technology & Engineering
Kind : eBook
Book Rating : 940/5 ( reviews)

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Book Synopsis Computational Hemodynamics – Theory, Modelling and Applications by : Jiyuan Tu

Download or read book Computational Hemodynamics – Theory, Modelling and Applications written by Jiyuan Tu. This book was released on 2015-02-24. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book’s approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.

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