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Author : Milap Nahata
Release : 2014-01-01
Genre : Medical
Kind : eBook
Book Rating : 144/5 ( reviews)
Book Synopsis Pediatric Drug Formulations by : Milap Nahata
Download or read book Pediatric Drug Formulations written by Milap Nahata. This book was released on 2014-01-01. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Milap C. Nahata
Release : 2011
Genre : Children
Kind : eBook
Book Rating : 328/5 ( reviews)
Book Synopsis Pediatric Drug Formulations by : Milap C. Nahata
Download or read book Pediatric Drug Formulations written by Milap C. Nahata. This book was released on 2011. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Release : 2018
Genre :
Kind : eBook
Book Rating : 120/5 ( reviews)
Book Synopsis Pediatric Drug Formulations 7th Edition by :
Download or read book Pediatric Drug Formulations 7th Edition written by . This book was released on 2018. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Daniel Bar-Shalom
Release : 2014-01-30
Genre : Medical
Kind : eBook
Book Rating : 113/5 ( reviews)
Book Synopsis Pediatric Formulations by : Daniel Bar-Shalom
Download or read book Pediatric Formulations written by Daniel Bar-Shalom. This book was released on 2014-01-30. Available in PDF, EPUB and Kindle. Book excerpt: Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.
Author : Nunzio Denora
Release : 2021-09-02
Genre : Science
Kind : eBook
Book Rating : 40X/5 ( reviews)
Book Synopsis Paediatric Formulation by : Nunzio Denora
Download or read book Paediatric Formulation written by Nunzio Denora. This book was released on 2021-09-02. Available in PDF, EPUB and Kindle. Book excerpt: The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.
