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Test No. 489: In Vivo Mammalian Alkaline Comet Assay

2014-09-26
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Release : 2014-09-26
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Kind : eBook
Book Rating : 173/5 ( reviews)

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Book Synopsis Test No. 489: In Vivo Mammalian Alkaline Comet Assay by : OECD

Download or read book Test No. 489: In Vivo Mammalian Alkaline Comet Assay written by OECD. This book was released on 2014-09-26. Available in PDF, EPUB and Kindle. Book excerpt: The in vivo alkaline single cell gel electrophoresis assay, also called alkaline Comet Assay is a method measuring DNA strand breaks in eukaryotic cells.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 489: In Vivo Mammalian Alkaline Comet Assay

2016-07-29
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Release : 2016-07-29
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Book Rating : 884/5 ( reviews)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 489: In Vivo Mammalian Alkaline Comet Assay by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 489: In Vivo Mammalian Alkaline Comet Assay written by OECD. This book was released on 2016-07-29. Available in PDF, EPUB and Kindle. Book excerpt: The in vivo alkaline single cell gel electrophoresis assay, also called alkaline Comet Assay is a method measuring DNA strand breaks in eukaryotic cells.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay

2022-06-30
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Release : 2022-06-30
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Book Rating : 067/5 ( reviews)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay written by OECD. This book was released on 2022-06-30. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the phosphatidylinositol glycan class A gene (Pig-a), as a reporter of somatic-cell gene mutation. In vivo gene mutation tests, such as the Pig-a assay, are especially relevant for assessing mutagenicity because physiological factors, such as absorption of the test chemical from the site of exposure, distribution of the test chemical throughout the test system via systemic circulation, and in vivo metabolism and DNA repair processes, all contribute to the mutagenic responses.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 482: Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro

1986-10-23
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 482: Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro PDF Online Free

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Release : 1986-10-23
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Book Rating : 44X/5 ( reviews)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 482: Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 482: Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro written by OECD. This book was released on 1986-10-23. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline for Unscheduled DNA Synthesis (UDS) in mammalian cells in vitro describes procedures utilizing primary cultures, human lymphocytes or established cell lines, to detect DNA repair synthesis after excision and removal of a stretch ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene

2016-07-29
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene PDF Online Free

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Release : 2016-07-29
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Book Rating : 906/5 ( reviews)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene written by OECD. This book was released on 2016-07-29. Available in PDF, EPUB and Kindle. Book excerpt: This TG includes two distinct in vitro mammalian gene mutation assays requiring two specific tk heterozygous cells lines: L5178Y tk+/-3.7.2C cells for the mouse lymphoma assay (MLA) and TK6 tk+/- cells for the TK6 assay.

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