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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies

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Release : 2018-06-27
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Book Rating : 229/5 ( reviews)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies written by OECD. This book was released on 2018-06-27. Available in PDF, EPUB and Kindle. Book excerpt: The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies

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Release : 2018-06-27
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Book Rating : 202/5 ( reviews)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies written by OECD. This book was released on 2018-06-27. Available in PDF, EPUB and Kindle. Book excerpt: The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition

Download OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition PDF Online Free

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Release : 2014-09-03
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Book Rating : 476/5 ( reviews)

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Book Synopsis OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition by : OECD

Download or read book OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition written by OECD. This book was released on 2014-09-03. Available in PDF, EPUB and Kindle. Book excerpt: This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test

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Release : 1986-10-23
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Book Rating : 482/5 ( reviews)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test written by OECD. This book was released on 1986-10-23. Available in PDF, EPUB and Kindle. Book excerpt: The mouse spot test detects presumed somatic mutations in fetal cells following transplacental absorption of the test substance. This is an in vivo test in mice in which developing embryos are exposed to a chemical (solid, liquid, vapour or ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies

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Release : 2018-06-27
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Book Rating : 180/5 ( reviews)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies written by OECD. This book was released on 2018-06-27. Available in PDF, EPUB and Kindle. Book excerpt: The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of ...

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