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Novel therapeutic approaches for gastrointestinal malignancies

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Release : 2020-10-01
Genre : Medical
Kind : eBook
Book Rating : 714/5 ( reviews)

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Book Synopsis Novel therapeutic approaches for gastrointestinal malignancies by : Ganji Purnachandra Nagaraju

Download or read book Novel therapeutic approaches for gastrointestinal malignancies written by Ganji Purnachandra Nagaraju. This book was released on 2020-10-01. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an up-to-date overview of gastrointestinal malignancies, including prevention, early detection, intervention, and life-extending therapeutics. It also assesses various biomarkers used for diagnostics, prognostics and prediction of response to chemoresistance. Further, it discusses the latest trends in the use of small-molecule targeted therapies and immunotherapies as single agents or combination with other treatments. Since resistance to radiation and chemotherapy contribute to the high recurrence and poor survival rates, improving the outcome for GI malignancies is dependent on the introduction of new biomarkers and therapeutic agents. Lastly, the book systematically investigates novel theranostics approaches using nanotechnology for the detection, diagnosis, and personalized treatment of GI malignancies.

Theranostics Approaches to Gastric and Colon Cancer

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Release : 2020-03-04
Genre : Medical
Kind : eBook
Book Rating : 178/5 ( reviews)

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Book Synopsis Theranostics Approaches to Gastric and Colon Cancer by : Ganji Seeta Rama Raju

Download or read book Theranostics Approaches to Gastric and Colon Cancer written by Ganji Seeta Rama Raju. This book was released on 2020-03-04. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer. The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer.

Gastrointestinal Malignancies

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Release : 2016-07-27
Genre : Medical
Kind : eBook
Book Rating : 444/5 ( reviews)

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Book Synopsis Gastrointestinal Malignancies by : David Bentrem

Download or read book Gastrointestinal Malignancies written by David Bentrem. This book was released on 2016-07-27. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively summarizes the current state of knowledge on malignancies of the gastrointestinal tract. Dedicated organ-based chapters evaluate current treatments and management and provide information on incidence, etiology and biological characteristics. The state of the art in the radiologic and endoscopic staging of gastrointestinal malignancies is described, and guidance is offered on the role of interventional radiology and interventional gastroenterology in the treatment of these challenging tumors. In addition, the book explores novel and evolving treatments, including personalized systemic therapy and minimally invasive surgical and radiology techniques, and addresses patient-reported outcomes and survivorship challenges. It closes by discussing animal models of gastrointestinal malignancies and examining the significance of the Ras superfamily of GTPases. It will be of benefit to all surgeons, oncologists and other specialists who treat these malignancies, as well as to trainees looking to increase their understanding of the field.

Handbook of Gastrointestinal Cancers

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Release : 2019-08-12
Genre : Medical
Kind : eBook
Book Rating : 136/5 ( reviews)

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Book Synopsis Handbook of Gastrointestinal Cancers by : Tanios Bekaii-Saab, MD

Download or read book Handbook of Gastrointestinal Cancers written by Tanios Bekaii-Saab, MD. This book was released on 2019-08-12. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Gastrointestinal Cancers is a practical guide to the management of colorectal, pancreatic, hepatocellular, gastric, and esophageal cancers as well as other cancers of the upper and lower gastrointestinal tract. Edited by a multidisciplinary group of oncologists from leading institutions, this book is an essential day-to-day reference for evidence-based treatment and patient care. The handbook focuses on treatment strategies and approaches to cancerous gastrointestinal tumors that are transforming the recent oncological landscape, including expert-given guidance on methods such as neoadjuvant and adjuvant chemotherapy, surgical transplant, radiation therapy, molecular diagnostic testing leading to molecularly targeted therapy, and immunotherapy. With so many advances in the current field, it is increasingly difficult for early-career practitioners to grasp the entirety of practices and for seasoned oncologists to keep up with newly approved therapies, side effects to treatments, and special clinical management considerations, but this handbook addresses it all. Organized by major gastrointestinal disease sites and featuring “How I Treat” case vignettes from world experts for common and uncommon management considerations, the handbook brings an experience-based perspective to these tough-to-treat areas. The treatment strategies and applications set forth in the chapters are pertinent to situations and decision-making encountered in practice. Handbook of Gastrointestinal Cancers is a valuable resource for medical oncologists, radiation oncologists, and surgeons treating and managing gastrointestinal cancers as well as trainees in medical, radiation, and surgical oncology programs needing an accessible point of care resource. KEY FEATURES: Provides treatment plans and recommendations for each stage of a range of gastrointestinal cancers, including colorectal, pancreatic, and hepatocellular cancers plus more Includes “How I Treat” patient vignettes told from the physician’s point of view within each clinical chapter Outlines special considerations for the elderly and for survivors of gastrointestinal cancers Highlights important clinical guidance on nutritional and palliative concerns commonly seen in patients with gastrointestinal cancers

Therapeutic Targets For Inflammation And Cancer: Novel Therapies For Digestive Diseases

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Release : 2017-04-20
Genre : Medical
Kind : eBook
Book Rating : 586/5 ( reviews)

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Book Synopsis Therapeutic Targets For Inflammation And Cancer: Novel Therapies For Digestive Diseases by : Chi-hin Cho

Download or read book Therapeutic Targets For Inflammation And Cancer: Novel Therapies For Digestive Diseases written by Chi-hin Cho. This book was released on 2017-04-20. Available in PDF, EPUB and Kindle. Book excerpt: This unique book deals with both inflammation and cancer in a single source of publication. They are seldom grouped together although it has been known that both diseases are closely associated, particularly in the gastrointestinal tract and liver. As the book touches on two such major areas of diseases in humans, it should be of interest to a wider audience of researchers and readers. It is noted that the book combines the effort of both basic scientists and clinicians from different countries with extensive experiences in molecular biology and clinical practice to unveil the most updated picture of the pathogenesis and therapeutic strategies in the treatment of inflammation and cancer in the digestive tract. In this regard, potential pathogenic modulators and also therapeutic options are widely discussed. These types of information would definitely broaden our knowledge in better understanding these diseases.

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