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Neuroglia Molecular Mechanisms in Psychiatric Disorders

2019-01-21
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Release : 2019-01-21
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Kind : eBook
Book Rating : 986/5 ( reviews)

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Book Synopsis Neuroglia Molecular Mechanisms in Psychiatric Disorders by : Caterina Scuderi

Download or read book Neuroglia Molecular Mechanisms in Psychiatric Disorders written by Caterina Scuderi. This book was released on 2019-01-21. Available in PDF, EPUB and Kindle. Book excerpt: Neuropsychiatric disorders have long been considered as specific dysfunctions of neuronal functions. Studies of the recent decade, however, have challenged this simplistic view, highlighting the important role played by neuroglial cells in the onset and/or progression of neuropsychiatric diseases. In the central nervous system (CNS) non-excitable neuroglia are represented by cells of ectodermal origin (astrocytes, mainly responsible for CNS homeostasis and oligodendrocytes that provide myelination and support for axons) and mesodermal origin (microglial cells that are scions of foetal macrophages entering the neural tube early in development; these cells provide for CNS defence and contribute to shaping neuronal networks). Pathological changes of neuroglia are complex; these changes are classified into reactive gliosis (astrogliosis, activation of microglia and hypertrophy of oligodendroglial precursors), gliodegeneration with loss of function and glial pathological remodelling. Combination of these processes defines the evolution of neurological diseases in general and neuropsychiatric disorders in particular. In this research topic we addressed the contribution of neuroglia to major neuropsychiatric pathologies including major depression, schizophrenia, and addictive disorders.

Neuroglia Molecular Mechanisms in Psychiatric Disorders

2019
Download Neuroglia Molecular Mechanisms in Psychiatric Disorders PDF Online Free

Author :
Release : 2019
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Neuroglia Molecular Mechanisms in Psychiatric Disorders by :

Download or read book Neuroglia Molecular Mechanisms in Psychiatric Disorders written by . This book was released on 2019. Available in PDF, EPUB and Kindle. Book excerpt: Neuropsychiatric disorders have long been considered as specific dysfunctions of neuronal functions. Studies of the recent decade, however, have challenged this simplistic view, highlighting the important role played by neuroglial cells in the onset and/or progression of neuropsychiatric diseases. In the central nervous system (CNS) non-excitable neuroglia are represented by cells of ectodermal origin (astrocytes, mainly responsible for CNS homeostasis and oligodendrocytes that provide myelination and support for axons) and mesodermal origin (microglial cells that are scions of foetal macrophages entering the neural tube early in development; these cells provide for CNS defence and contribute to shaping neuronal networks). Pathological changes of neuroglia are complex; these changes are classified into reactive gliosis (astrogliosis, activation of microglia and hypertrophy of oligodendroglial precursors), gliodegeneration with loss of function and glial pathological remodelling. Combination of these processes defines the evolution of neurological diseases in general and neuropsychiatric disorders in particular. In this research topic we addressed the contribution of neuroglia to major neuropsychiatric pathologies including major depression, schizophrenia, and addictive disorders.

The NMDA Receptors

2017-02-08 Medical
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Release : 2017-02-08
Genre : Medical
Kind : eBook
Book Rating : 952/5 ( reviews)

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Book Synopsis The NMDA Receptors by : Kenji Hashimoto

Download or read book The NMDA Receptors written by Kenji Hashimoto. This book was released on 2017-02-08. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a history of and an update on the functional status of the NMDA receptors. The NMDA receptors are essential for neuronal development, synaptic plasticity, learning, and cell survival. It covers molecular, cellular, anatomical, biochemical, and behavioral aspects, to highlight their distinctive regulatory properties, their functional significance, and their therapeutic potential in a number of diseases. A group of international experts discuss the development of NMDA receptors, their basic functions, and how they are implicated in a wide range of diseases including depression, psychosis, and pain.

New Mechanisms of Action of Natural Antioxidants in Health and Disease

2020-07-03 Medical
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Release : 2020-07-03
Genre : Medical
Kind : eBook
Book Rating : 682/5 ( reviews)

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Book Synopsis New Mechanisms of Action of Natural Antioxidants in Health and Disease by : Silvana Hrelia

Download or read book New Mechanisms of Action of Natural Antioxidants in Health and Disease written by Silvana Hrelia. This book was released on 2020-07-03. Available in PDF, EPUB and Kindle. Book excerpt: This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.

Systems Neuroscience in Depression

2016-03-16 Psychology
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Release : 2016-03-16
Genre : Psychology
Kind : eBook
Book Rating : 286/5 ( reviews)

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Book Synopsis Systems Neuroscience in Depression by : Thomas Frodl

Download or read book Systems Neuroscience in Depression written by Thomas Frodl. This book was released on 2016-03-16. Available in PDF, EPUB and Kindle. Book excerpt: Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with a background from neurodevelopment and neural understanding as well as novel treatment approaches for depression. This book covers basic developmental aspects and depressive psychopathology, as well as the basic scientific background from animal models and experimental research. Current advances in systems neuroscience are highlighted in studies from child and adolescent psychiatry. Integrated approaches are presented with regards to genetics, neuroimaging and neuroinflammation as well as neuroendocrinology. The field of systems and network neuroscience is evolving rapidly and this book provides a greatly needed resource for researchers and practitioners in systems neuroscience and psychiatry. - Knowledge covering the whole life span from early to later life - Comprehensively written chapters developing from molecules via epigenetics and neural circuits to clinical neuroscience - Understanding the neurobiology of major depressive disorder - Integrating stress and environmental factors with molecular underpinnings - More than 25 illustrations and tables

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