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Neuroepigenetics and Mental Illness

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Release : 2018-07-30
Genre : Science
Kind : eBook
Book Rating : 934/5 ( reviews)

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Book Synopsis Neuroepigenetics and Mental Illness by : Bart P.F. Rutten

Download or read book Neuroepigenetics and Mental Illness written by Bart P.F. Rutten. This book was released on 2018-07-30. Available in PDF, EPUB and Kindle. Book excerpt: Neuroepigenetics and Mental Illness, Volume 158, the latest release in the Progress in Molecular Biology and Translational Science series, seeks to provide the most topical, informative, and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series seeks to provide readers with in-depth knowledge of important molecular biological aspects of organismal physiology and function, with this release focusing on Neuroepigenetics in mental illness, Neuroepigenetics of development and neurodevelopmental disorder, Neuroepigenetics of aging and age-related neurodegenerative disorders, Neuroepigenetics of prenatal psychological stress, Neuroepigenetics of the HPA axis, Neuroepigenetics of the serotonergic system, and more. - Presents updated volumes comprising 15-20 chapters, allowing comprehensive coverage on a topic - Uses tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided in each chapter

Epigenetics in Psychiatry

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Release : 2021-08-21
Genre : Science
Kind : eBook
Book Rating : 780/5 ( reviews)

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Book Synopsis Epigenetics in Psychiatry by : Jacob Peedicayil

Download or read book Epigenetics in Psychiatry written by Jacob Peedicayil. This book was released on 2021-08-21. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth. - Fully revised to discuss new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics in psychiatric disease - Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and proteins - Catalyzes knowledge discovery in both basic epigenetic biology and epigenetic targets for drug discovery - Provides guidance in research methods and protocols, as well how to employ data from consortia, single cell analysis, and epigenome-wide association studies (EWAS) - Features chapter contributions from international leaders in the field

Neuroepigenomics in Aging and Disease

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Release : 2017-05-18
Genre : Science
Kind : eBook
Book Rating : 896/5 ( reviews)

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Book Synopsis Neuroepigenomics in Aging and Disease by : Raul Delgado-Morales

Download or read book Neuroepigenomics in Aging and Disease written by Raul Delgado-Morales. This book was released on 2017-05-18. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan: from neurodevelopment/childhood (Rett Syndrome, Rubinstein-Taybi, autism), adolescence (eating disorders, drug addiction, anxiety), adulthood (depression, schizophrenia, amyotrophic lateral sclerosis, Huntington’s disease) and elderly (Alzheimer’s disease, Parkinson’s disease). The book also covers the three major players on neuroepigenomic mechanisms: histones alterations, DNA modifications and non-coding RNAs, their roles at the molecular and cellular level and the impact of their alterations on neuronal function and behavior. Finally, a special chapter on state-of-the-art technologies helps the reader not only to understand epigenetic driven changes in human cognition and diseases but also the methodology that will help to generate paradigm shifts on our understanding of brain function and the role of the neuroepigenome in human diseases.

Arousal in Neurological and Psychiatric Diseases

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Release : 2019-06-18
Genre : Medical
Kind : eBook
Book Rating : 937/5 ( reviews)

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Book Synopsis Arousal in Neurological and Psychiatric Diseases by : Edgar Garcia-Rill

Download or read book Arousal in Neurological and Psychiatric Diseases written by Edgar Garcia-Rill. This book was released on 2019-06-18. Available in PDF, EPUB and Kindle. Book excerpt: Arousal in Neurological and Psychiatric Diseases focuses on the dysregulation of arousal found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it presents in each disorder, and the most appropriate treatment(s). The book also imparts the understanding of the RAS as a system that not only modulates waking, but also survival mechanisms, such as fight vs. flight responses and other reflexes. This book helps neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease. In addition, it promotes therapies that can alter the severity and manifestation of multiple disorders. - Provides a comprehensive overview of the basic mechanisms behind dysregulation of arousal in neurological and psychiatric disorders - Describes, in detail, the function of the Reticular Activating System with respect to higher functions, motor control and the intertwining of arousal and motor disorders - Covers multiple neurological disorders, including epilepsy, Alzheimer's disease, Parkinson's disease and autism

The Epigenetics Revolution

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Release : 2012-03-06
Genre : Science
Kind : eBook
Book Rating : 714/5 ( reviews)

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Book Synopsis The Epigenetics Revolution by : Nessa Carey

Download or read book The Epigenetics Revolution written by Nessa Carey. This book was released on 2012-03-06. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

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