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Myelin Repair and Neuroprotection in Multiple Sclerosis

2012-08-31 Medical
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Release : 2012-08-31
Genre : Medical
Kind : eBook
Book Rating : 183/5 ( reviews)

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Book Synopsis Myelin Repair and Neuroprotection in Multiple Sclerosis by : Ian D. Duncan

Download or read book Myelin Repair and Neuroprotection in Multiple Sclerosis written by Ian D. Duncan. This book was released on 2012-08-31. Available in PDF, EPUB and Kindle. Book excerpt: Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclerosis (MS). A number of research frontiers still exist in this challenging disease. The cause remains elusive, preventing breakthroughs in its prevention. The move towards oral immunomodulatory therapies has been a major advance, as has the finding of new genes linked to susceptibility that may open the door to new therapeutic approaches. However, a frontier that has been making significant strides in recent years has been that surrounding the neurobiology of myelin regeneration and axon protection: such have been the advances that clinical translation is on the cusp of being achieved. Two broad approaches to therapeutic enhancement of remyelination are envisaged: promoting endogenous remyelination by targeting cells present in the CNS, or, replacing lost myelinating cells from exogenous sources. Current research on oligodendrocyte biology, the pathology of MS, imaging of lesions and the biology of remyelination are paving the way toward opening this new translational frontier. Professor Duncan and Professor Franklin have assembled a broad group of experts in the fields of glial cell biology, neuropathology, radiology and clinical neurology to provide the background toward taking remyelination from experimented models into MS patients.

Multiple Sclerosis

1978 Multiple sclerosis
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Release : 1978
Genre : Multiple sclerosis
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Multiple Sclerosis by : National Institute of Neurological and Communicative Disorders and Stroke. Office of Scientific and Health Reports

Download or read book Multiple Sclerosis written by National Institute of Neurological and Communicative Disorders and Stroke. Office of Scientific and Health Reports. This book was released on 1978. Available in PDF, EPUB and Kindle. Book excerpt:

Verbatim Record of the 1422nd Meeting, Held at Headquarters, New York, on Thursday, 15 July 1993

1993
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Release : 1993
Genre :
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Book Rating : /5 ( reviews)

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Book Synopsis Verbatim Record of the 1422nd Meeting, Held at Headquarters, New York, on Thursday, 15 July 1993 by :

Download or read book Verbatim Record of the 1422nd Meeting, Held at Headquarters, New York, on Thursday, 15 July 1993 written by . This book was released on 1993. Available in PDF, EPUB and Kindle. Book excerpt:

Multiple Sclerosis 3, Volume 34 E-Book

2009-10-29 Medical
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Release : 2009-10-29
Genre : Medical
Kind : eBook
Book Rating : 294/5 ( reviews)

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Book Synopsis Multiple Sclerosis 3, Volume 34 E-Book by : Claudia Lucchinetti

Download or read book Multiple Sclerosis 3, Volume 34 E-Book written by Claudia Lucchinetti. This book was released on 2009-10-29. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Sclerosis 3 emphasizes the latest in the pharmacologic treatment of this incurable inflammatory demyelinating disorder. Primary editors Claudia Lucchinetti, MD, and Reinhard Hohlfeld, MD, with the aid of all new contributors, present a complete and current reference on multiple sclerosis that includes discussions of such hot topics as Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair. Distinguish between MS and other similar demyelinating disorders and know the best and most aggressive methods of treatment. This title in the Blue Books of Neurology series is exactly what you need to treat the disease and its relapses. Covers the latest clinical advances and relevant discussions—Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair—to bring you up to date and keep your practice state-of-the-art. Features a greater emphasis on practical management to help you determine the type of multiple sclerosis and the best course of therapy. Focuses on pharmaceutical therapies so you know the best and most aggressive methods and which drugs to use for treatment. Includes extensive information on differential diagnosis so that you can clearly distinguish between multiple sclerosis and other similar demyelinating disorders. Presents expert new editors and experienced contributing authors for the most current and relevant practice information. Emphasizes the pharmacologic management of patients with multiple sclerosis to address treating the actual disease and its relapses as well as treating the symptoms.

Multiple Sclerosis

2007-10-27 Medical
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Release : 2007-10-27
Genre : Medical
Kind : eBook
Book Rating : 552/5 ( reviews)

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Book Synopsis Multiple Sclerosis by : Michael Olek

Download or read book Multiple Sclerosis written by Michael Olek. This book was released on 2007-10-27. Available in PDF, EPUB and Kindle. Book excerpt: A synthesis of current concepts about the evaluation, treatment, and future directions in MS. On the evaluation side, the authors review the use of MRI, magnetic resonance spectroscopy, functional MRI, and three-dimensional MRI, and consider the rapidly developing body of pathologic information they have yielded. On the treatment side, the focus is on recently approved medications (Novantrone), new indications for medications (CHAMPS Trial), medications in development (Oral Interferon Tau, Oral Copaxone, and Oral Cellcept), immunosuppressive therapy for both progressive disease and symptomatic therapy; the current medications for treating relapsing-remitting MS (Avonex, Betaseron, and Copaxone) are also discussed. For future directions, the authors present the current best thinking, as well as the latest discoveries in immunology relating to MS, including groundbreaking B-cell research and its applications to specific immunotherapies, and the use of immune markers for tracking the disease.

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