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Multiscale Cancer Modeling

2010-12-08 Mathematics
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Release : 2010-12-08
Genre : Mathematics
Kind : eBook
Book Rating : 422/5 ( reviews)

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Book Synopsis Multiscale Cancer Modeling by : Thomas S. Deisboeck

Download or read book Multiscale Cancer Modeling written by Thomas S. Deisboeck. This book was released on 2010-12-08. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat

Multiscale Modeling of Cancer

2010-09-09 Technology & Engineering
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Release : 2010-09-09
Genre : Technology & Engineering
Kind : eBook
Book Rating : 504/5 ( reviews)

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Book Synopsis Multiscale Modeling of Cancer by : Vittorio Cristini

Download or read book Multiscale Modeling of Cancer written by Vittorio Cristini. This book was released on 2010-09-09. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.

An Introduction to Physical Oncology

2017-06-26 Mathematics
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Release : 2017-06-26
Genre : Mathematics
Kind : eBook
Book Rating : 364/5 ( reviews)

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Book Synopsis An Introduction to Physical Oncology by : Vittorio Cristini

Download or read book An Introduction to Physical Oncology written by Vittorio Cristini. This book was released on 2017-06-26. Available in PDF, EPUB and Kindle. Book excerpt: Physical oncology has the potential to revolutionize cancer research and treatment. The fundamental rationale behind this approach is that physical processes, such as transport mechanisms for drug molecules within tissue and forces exchanged by cancer cells with tissue, may play an equally important role as biological processes in influencing progression and treatment outcome. This book introduces the emerging field of physical oncology to a general audience, with a focus on recent breakthroughs that help in the design and discovery of more effective cancer treatments. It describes how novel mathematical models of physical transport processes incorporate patient tissue and imaging data routinely produced in the clinic to predict the efficacy of many cancer treatment approaches, including chemotherapy and radiation therapy. By helping to identify which therapies would be most beneficial for an individual patient, and quantifying their effects prior to actual implementation in the clinic, physical oncology allows doctors to design treatment regimens customized to each patient’s clinical needs, significantly altering the current clinical approach to cancer treatment and improving the outcomes for patients.

Multiscale Modeling of Cancer

2009 Cancer
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Release : 2009
Genre : Cancer
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Multiscale Modeling of Cancer by : Kevin Flores

Download or read book Multiscale Modeling of Cancer written by Kevin Flores. This book was released on 2009. Available in PDF, EPUB and Kindle. Book excerpt:

Cellular Potts Models

2013-03-26 Mathematics
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Release : 2013-03-26
Genre : Mathematics
Kind : eBook
Book Rating : 795/5 ( reviews)

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Book Synopsis Cellular Potts Models by : Marco Scianna

Download or read book Cellular Potts Models written by Marco Scianna. This book was released on 2013-03-26. Available in PDF, EPUB and Kindle. Book excerpt: This work shows how the cellular Potts model can be used as a framework for model building and how extended models can achieve even better biological practicality, accuracy, and predictive power. It focuses on ways to integrate and interface the basic cellular Potts model at the mesoscopic scale with approaches that accurately model microscopic dynamics. These extensions are designed to create a nested and hybrid environment, where the evolution of a biological system is realistically driven by the constant interplay and flux of information between the different levels of description.

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