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Molecular Signaling of Mammalian Inner Ear Development

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Author :
Release : 2013
Genre : Medical
Kind : eBook
Book Rating : 001/5 ( reviews)

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Book Synopsis Molecular Signaling of Mammalian Inner Ear Development by : Dorothy A. Frenz

Download or read book Molecular Signaling of Mammalian Inner Ear Development written by Dorothy A. Frenz. This book was released on 2013. Available in PDF, EPUB and Kindle. Book excerpt: The inner ear originates from an ectodermal thickening, the otic placode, which lies adjacent to the developing hindbrain. Complex interactions between regulatory signaling molecules guide development of the simple otic placode into the elaborate, multifunctional organs of hearing and balance. This book delves into recent research in the field, focusing on successive stages of inner ear development and how they are influenced by the coordinate activity of signaling molecules. This book begins with an overview of the evolutionary adaptation of the organ of Corti (organ of hearing) and the molecular signals that characterize ancestral development of the inner ear. Following this, the topics addressed include the complex signaling interactions underlying induction of the otic placode, key molecular mediators influencing inner ear development and patterning, genetic signaling of the vestibular (balance) system and clinical correlations to human balance disorders, commitment to auditory hair cell fate, and reliance of the inner ear on retinoic acid, a biologically-active derivative of vitamin A, for appropriate development. This timely and comprehensive book provides an excellent resource for researchers, clinician-scientists and students alike.

Development of Auditory and Vestibular Systems-3: Molecular Development of the Inner Ear

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Release : 2003-12-15
Genre : Science
Kind : eBook
Book Rating : 913/5 ( reviews)

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Book Synopsis Development of Auditory and Vestibular Systems-3: Molecular Development of the Inner Ear by : Raymond Romand

Download or read book Development of Auditory and Vestibular Systems-3: Molecular Development of the Inner Ear written by Raymond Romand. This book was released on 2003-12-15. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to advances in genetics and genomics, research on inner ear development has flourished. Better approaches and experimental models have shed light on the function of a variety of vertebrate genes and their related proteins. This latest volume of Current Topics in Developmental Biology delves into this new research to show how the discovery of more genes involved in the development of the inner ear leads to the generation of new models that examine a wealth of issues -- from the origins of human deafness to the roles of genes during inner ear induction, development and differentiation. The wide variety of experimental approaches will help readers to understand the broad range of issues related to inner ear morphogenesis and other concepts from complementary areas of investigation. This state-of-the-art overview will be essential reading for researchers, clinicians and students alike.* Scores of high-quality, full- color figures* Detailed schemes on the structure and timing of ear development* Current Topics in Developmental Biology is the longest-running forum for contemporary issues in developmental biology

Development of the Inner Ear

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Author :
Release : 2006-03-04
Genre : Science
Kind : eBook
Book Rating : 781/5 ( reviews)

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Book Synopsis Development of the Inner Ear by : Matthew Kelley

Download or read book Development of the Inner Ear written by Matthew Kelley. This book was released on 2006-03-04. Available in PDF, EPUB and Kindle. Book excerpt: The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to betterunderstandthefundamentaltheoriesanddatain?eldsofhearingthatthey may not normally follow closely. Each volume presents a particular topic comprehensively, and each servesas a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature. Eachvolumeintheseriesconsistsofafewsubstantialchaptersonaparticular topic. In some cases, the topics will be ones of traditional interest for which there is a substantial body of data and theory, such as auditory neuroanatomy (Vol. 1) and neurophysiology (Vol. 2). Other volumes in the series deal with topics that have begun to mature more recently, suchasdevelopment,plasticity, and computational models of neural processing. In many cases, the series - itorsarejoinedbyaco-editorhavingspecialexpertiseinthetopicofthevolume.

Development of Auditory and Vestibular Systems

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Release : 2014-05-23
Genre : Science
Kind : eBook
Book Rating : 088/5 ( reviews)

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Book Synopsis Development of Auditory and Vestibular Systems by : Raymond Romand

Download or read book Development of Auditory and Vestibular Systems written by Raymond Romand. This book was released on 2014-05-23. Available in PDF, EPUB and Kindle. Book excerpt: Development of Auditory and Vestibular Systems fourth edition presents a global and synthetic view of the main aspects of the development of the stato-acoustic system. Unique to this volume is the joint discussion of two sensory systems that, although close at the embryological stage, present divergences during development and later reveal conspicuous functional differences at the adult stage. This work covers the development of auditory receptors up to the central auditory system from several animal models, including humans. Coverage of the vestibular system, spanning amphibians to effects of altered gravity during development in different species, offers examples of the diversity and complexity of life at all levels, from genes through anatomical form and function to, ultimately, behavior. The new edition of Development of Auditory and Vestibular Systems will continue to be an indispensable resource for beginning scientists in this area and experienced researchers alike. - Full-color figures illustrate the development of the stato-acoustic system pathway - Covers a broad range of species, from drosophila to humans, demonstrating the diversity of morphological development despite similarities in molecular processes involved at the cellular level - Discusses a variety of approaches, from genetic-molecular biology to psychophysics, enabling the investigation of ontogenesis and functional development

The Primary Auditory Neurons of the Mammalian Cochlea

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Release : 2015-10-06
Genre : Medical
Kind : eBook
Book Rating : 311/5 ( reviews)

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Book Synopsis The Primary Auditory Neurons of the Mammalian Cochlea by : Alain Dabdoub

Download or read book The Primary Auditory Neurons of the Mammalian Cochlea written by Alain Dabdoub. This book was released on 2015-10-06. Available in PDF, EPUB and Kindle. Book excerpt: This volume details the essential role of the spiral ganglion neurons. The volume elucidates and characterizes their development, their environment, their electrophysiological characteristics, their connectivity to their targets in the inner ear and the brain, and discusses the potential for their regeneration. A comprehensive review about the spiral ganglion neurons is important for researchers not only in the inner ear field but also in development, neuroscience, biophysics as well as neural networks researchers. The chapters are authored by leading researchers in the field.

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