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Molecular Neurobiology of Alzheimer Disease and Related Disorders

2004 Medical
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Release : 2004
Genre : Medical
Kind : eBook
Book Rating : 03X/5 ( reviews)

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Book Synopsis Molecular Neurobiology of Alzheimer Disease and Related Disorders by : Masatoshi Takeda

Download or read book Molecular Neurobiology of Alzheimer Disease and Related Disorders written by Masatoshi Takeda. This book was released on 2004. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimers disease affects 6-10% of the elderly population, causing impairment in cognitive functions and significant disability in daily living for more than ten years. Neurofibrillary tangles, amyloid deposits and neuronal loss are the three hallmarks of Alzheimers disease. Due to insolubility of these unique structures in Alzheimer brain tissue, they were very difficult to study by usual biochemical methods in the past. Active research is now going on to elucidate the pathogenesis of Alzheimers disease. Major topics of neurobiological study of Alzheimers disease include the unraveling of the molecular mechanism of neurofibrillary tangle formation in neuronal and glial cells, the molecular processing of amyloid precursor protein in intracellular organella and in extra-cellular space, and the molecular mechanism of neuronal loss. The articles in this book were selected from contributions presented by leading scientists in this field at the international symposium which took place in Osaka in 2002. This publication is essential reading for all researchers, clinicians, basic and social scientists, neurologists and psychiatrists to promote the understanding of this formidable disease.

Neurobiology of Alzheimer's Disease

2007-05-03 Medical
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Release : 2007-05-03
Genre : Medical
Kind : eBook
Book Rating : 584/5 ( reviews)

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Book Synopsis Neurobiology of Alzheimer's Disease by : David Dawbarn

Download or read book Neurobiology of Alzheimer's Disease written by David Dawbarn. This book was released on 2007-05-03. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease is the most common form of dementia in the elderly; 450,000 people in the UK and 4.5 million people in the USA suffer with this disease. This 3rd edition of Neurobiology of Alzheimer's Disease gives a comprehensive and readable introduction to the disease, from molecular pathology to clinical practice. The book is intended for readers new to the field, and it also covers an extensive range of themes for those with in-depth knowledge of Alzheimer's disease. It will therefore act either as an introduction to the whole field of neurodegeneration or it will help experienced researchers to access the latest research in specialist topics. Each chapter is written by eminent scientists leading their fields in neuropathology, clinical practice and molecular neurobiology; appendices detail disease-associated proteins, their sequences, familial mutations and known structures. It will be essential reading for students interested in neurodegeneration and for researchers and clinicians, giving a coherent and cohesive approach to the whole area of research, and allowing access at different levels. For those in the pharmaceutical industry it describes the underlying molecular mechanisms involved in the pathogenesis of Alzheimer's disease and explains how current and potential therapeutics may work.

Neurobiology of Alzheimer's Disease

2001 Medical
Download Neurobiology of Alzheimer's Disease PDF Online Free

Author :
Release : 2001
Genre : Medical
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Neurobiology of Alzheimer's Disease by : David Dawbarn

Download or read book Neurobiology of Alzheimer's Disease written by David Dawbarn. This book was released on 2001. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition of a book first published in 1995, presents an accessible overview of Alzheimer's disease, with an emphasis on research into the molecular mechanisms of neuronal degeneration. International experts have provided in-depth reviews of their areas of expertise, including coverage of the key molecules known to be involved, such as Ab, tau, apolipoprotein E and the presenilins. Other areas covered include neuropathology, genetics, neurochemical pathology, inflammation, diagnosis, models of the disease and opportunities for treatment, employing both existing and emerging drug therapies. The book will provide a readable introduction for those new to the subject, as well as covering a wide range of specialist topics for more experienced researchers and those interested in the overlap with other related specialist areas. Also included are appendices detailing gene and protein information on APP, tau, the presenilins, apolipoprotein E and the newly cloned therapeutic target, BACE.

Molecular Biology of Neurodegenerative Diseases: Visions for the Future - Part B

2021-01-14 Science
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Release : 2021-01-14
Genre : Science
Kind : eBook
Book Rating : 446/5 ( reviews)

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Book Synopsis Molecular Biology of Neurodegenerative Diseases: Visions for the Future - Part B by :

Download or read book Molecular Biology of Neurodegenerative Diseases: Visions for the Future - Part B written by . This book was released on 2021-01-14. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Part B, Volume 177 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, and more. - Includes comprehensive coverage of molecular biology - Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided - Contains contributions from renowned experts in the field

Alzheimer's Disease

2007-02-16 Medical
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Release : 2007-02-16
Genre : Medical
Kind : eBook
Book Rating : 353/5 ( reviews)

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Book Synopsis Alzheimer's Disease by : Sangram S. Sisodia

Download or read book Alzheimer's Disease written by Sangram S. Sisodia. This book was released on 2007-02-16. Available in PDF, EPUB and Kindle. Book excerpt: This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.

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