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Molecular Genetics of Pediatric Orthopaedic Disorders

2015-03-04 Medical
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Release : 2015-03-04
Genre : Medical
Kind : eBook
Book Rating : 69X/5 ( reviews)

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Book Synopsis Molecular Genetics of Pediatric Orthopaedic Disorders by : Carol A. Wise

Download or read book Molecular Genetics of Pediatric Orthopaedic Disorders written by Carol A. Wise. This book was released on 2015-03-04. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic technology development has outpaced expectations and is enabling gene discovery for disorders that were previously intractable with traditional genetic methods. Included in this latter category are common disorders that display multigenic inheritance, sporadic disorders, and very rare conditions that are difficult to ascertain. Simultaneously, the study of pediatric orthopaedic disorders has been continuously refined and updated, highlighting a number of likely genetic conditions that are as yet unsolved. Molecular Genetics of Pediatric Orthopaedic Disorders updates researchers and clinicians of new developments of pediatric orthopaedic genetics. The chapters inform the audience on the revolution in new genomic methods and the impact this is having on potential study designs and the potential to discover genetic causes of many unsolved orthopaedic conditions. Recent examples have been included of pediatric orthopaedic conditions, both rare and common, that are being solved with these new methods. The book also educates pediatric orthopedic clinicians and geneticists on our understanding of the biology of “classic” genetic diseases that were derived from prior genetic studies. Chapters include biobanks and strategies for studying very rare disorders, genes and pathways causing primordial dwarfism, and notch signaling in congenital scoliosis, and more.​

Genetics for Orthopedic Surgeons

2002 Orthopedic
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Release : 2002
Genre : Orthopedic
Kind : eBook
Book Rating : 420/5 ( reviews)

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Book Synopsis Genetics for Orthopedic Surgeons by : Ian D. Young

Download or read book Genetics for Orthopedic Surgeons written by Ian D. Young. This book was released on 2002. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology is one of the fastest growing areas of medical research and now impinges on almost every medical discipline. This work provides an up-to-date overview of developments in molecular genetics as they relate to orthopedic practice.

Pediatric Orthopedic Deformities

2002-01-16 Medical
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Release : 2002-01-16
Genre : Medical
Kind : eBook
Book Rating : 568/5 ( reviews)

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Book Synopsis Pediatric Orthopedic Deformities by : Frederic Shapiro

Download or read book Pediatric Orthopedic Deformities written by Frederic Shapiro. This book was released on 2002-01-16. Available in PDF, EPUB and Kindle. Book excerpt: Specific operative and nonoperative techniques and their results are stressed. The book is extensively illustrated with drawings, most of which were made for this book, microscopy photos, and serial radiographs. The reader learns of pediatric orthopedic deformity in relation to normal and abnormal developmental biology, the worsening of untreated disease with growth, and the diagnostic and treatment interventions required based on the stage of progression. * Treatments are correlated with the pathologic state of the disorder* Discusses disorders from earliest onset to the final state showing how the altered biology leads to progressively greater clinical deformity* Initial chapter focuses on development bone biology stressing a broad based approach involving histologic, gene and molecular, and biomechanical features* Subsequent chapters discuss the pathogenesis of the various deformities, natural history, radiographic and imaging findings and orthopaedic and surgical management

Pediatric Orthopedic Deformities, Volume 1

2015-12-20 Medical
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Release : 2015-12-20
Genre : Medical
Kind : eBook
Book Rating : 293/5 ( reviews)

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Book Synopsis Pediatric Orthopedic Deformities, Volume 1 by : Frederic Shapiro

Download or read book Pediatric Orthopedic Deformities, Volume 1 written by Frederic Shapiro. This book was released on 2015-12-20. Available in PDF, EPUB and Kindle. Book excerpt: Developmental biology of normal bone and cartilage including histogenesis, molecular/gene and biomechanical aspects is updated and expanded. The book outlines the biology of: bone repair with differing mechanical environments; cartilage repair at articular and physeal sites; and distraction osteogenesis. The generously illustrated text provides an in-depth presentation of the interplay between normal developmental biology, abnormal pathologic states and the influence of operative and non-operative orthopedic interventions on childhood orthopedic deformity. Thirty-four principles underlying the development, progression and management of skeletal deformity in the growing child are defined. Orthopedic management including surgical treatment is discussed for: skeletal dysplasias; epiphyseal growth plate fracture-separations; lower extremity length discrepancies; and deformities of joints and epiphyses due to metabolic, inflammatory, infectious, hematologic, and neoplastic disorders. Treatments are related to extent of deformity, remodeling post-surgery and possible recurrence. This 2nd edition of Pediatric Orthopedic Deformities has been expanded to cover more regions and disorders and is being presented in 3 volumes.

Practice of Pediatric Orthopedics

2006 Medical
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Release : 2006
Genre : Medical
Kind : eBook
Book Rating : 183/5 ( reviews)

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Book Synopsis Practice of Pediatric Orthopedics by :

Download or read book Practice of Pediatric Orthopedics written by . This book was released on 2006. Available in PDF, EPUB and Kindle. Book excerpt: Designed for general orthopedists, residents, pediatricians, physical therapists, and students, Practice of Pediatric Orthopedics, Second Edition is a practical, authoritative, generously illustrated, full-color how-to guide to the essentials of pediatric orthopedics. Dr. Staheli provides current, clinically proven, mainstream, whole child oriented management recommendations for musculoskeletal problems in children. The book features over 2,300 full-color photographs and drawings and numerous flowcharts to guide patient management. For this updated and expanded Second Edition, Dr. Staheli has recruited eight distinguished co-authors to contribute new information. Illustrations have been updated and many new illustrations have been added. The upper limb and hand chapters have been separated and expanded.

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