Share

Biological Modeling and Simulation

2008-07-25 Science
Download Biological Modeling and Simulation PDF Online Free

Author :
Release : 2008-07-25
Genre : Science
Kind : eBook
Book Rating : 844/5 ( reviews)

GET EBOOK


Book Synopsis Biological Modeling and Simulation by : Russell Schwartz

Download or read book Biological Modeling and Simulation written by Russell Schwartz. This book was released on 2008-07-25. Available in PDF, EPUB and Kindle. Book excerpt: A practice-oriented survey of techniques for computational modeling and simulation suitable for a broad range of biological problems. There are many excellent computational biology resources now available for learning about methods that have been developed to address specific biological systems, but comparatively little attention has been paid to training aspiring computational biologists to handle new and unanticipated problems. This text is intended to fill that gap by teaching students how to reason about developing formal mathematical models of biological systems that are amenable to computational analysis. It collects in one place a selection of broadly useful models, algorithms, and theoretical analysis tools normally found scattered among many other disciplines. It thereby gives the aspiring student a bag of tricks that will serve him or her well in modeling problems drawn from numerous subfields of biology. These techniques are taught from the perspective of what the practitioner needs to know to use them effectively, supplemented with references for further reading on more advanced use of each method covered. The text, which grew out of a class taught at Carnegie Mellon University, covers models for optimization, simulation and sampling, and parameter tuning. These topics provide a general framework for learning how to formulate mathematical models of biological systems, what techniques are available to work with these models, and how to fit the models to particular systems. Their application is illustrated by many examples drawn from a variety of biological disciplines and several extended case studies that show how the methods described have been applied to real problems in biology.

Mathematical Modeling in Systems Biology

2022-06-07 Science
Download Mathematical Modeling in Systems Biology PDF Online Free

Author :
Release : 2022-06-07
Genre : Science
Kind : eBook
Book Rating : 829/5 ( reviews)

GET EBOOK


Book Synopsis Mathematical Modeling in Systems Biology by : Brian P. Ingalls

Download or read book Mathematical Modeling in Systems Biology written by Brian P. Ingalls. This book was released on 2022-06-07. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

Mathematical Models in Molecular Cellular Biology

1980 Mathematics
Download Mathematical Models in Molecular Cellular Biology PDF Online Free

Author :
Release : 1980
Genre : Mathematics
Kind : eBook
Book Rating : 258/5 ( reviews)

GET EBOOK


Book Synopsis Mathematical Models in Molecular Cellular Biology by : Lee A. Segel

Download or read book Mathematical Models in Molecular Cellular Biology written by Lee A. Segel. This book was released on 1980. Available in PDF, EPUB and Kindle. Book excerpt: Interest in theoretical biology is rapidly growing and this 1981 book attempts to make the theory more accessible to experimentalists. Its primary purpose is to demonstrate to experimental molecular and cellular biologists the possible usefulness of mathematical models. Biologists with a basic command of calculus should be able to learn from the book what assumptions are implied by various types of equations, to understand in broad outline a number of major theoretical concepts, and to be aware of some of the difficulties connected with analytical and numerical solutions of mathematical problems. Thus they should be able to appreciate the significance of theoretical papers in their fields and to communicate usefully with theoreticians in the course of their work.

Discrete and Topological Models in Molecular Biology

2013-12-23 Computers
Download Discrete and Topological Models in Molecular Biology PDF Online Free

Author :
Release : 2013-12-23
Genre : Computers
Kind : eBook
Book Rating : 937/5 ( reviews)

GET EBOOK


Book Synopsis Discrete and Topological Models in Molecular Biology by : Nataša Jonoska

Download or read book Discrete and Topological Models in Molecular Biology written by Nataša Jonoska. This book was released on 2013-12-23. Available in PDF, EPUB and Kindle. Book excerpt: Theoretical tools and insights from discrete mathematics, theoretical computer science, and topology now play essential roles in our understanding of vital biomolecular processes. The related methods are now employed in various fields of mathematical biology as instruments to "zoom in" on processes at a molecular level. This book contains expository chapters on how contemporary models from discrete mathematics – in domains such as algebra, combinatorics, and graph and knot theories – can provide perspective on biomolecular problems ranging from data analysis, molecular and gene arrangements and structures, and knotted DNA embeddings via spatial graph models to the dynamics and kinetics of molecular interactions. The contributing authors are among the leading scientists in this field and the book is a reference for researchers in mathematics and theoretical computer science who are engaged with modeling molecular and biological phenomena using discrete methods. It may also serve as a guide and supplement for graduate courses in mathematical biology or bioinformatics, introducing nontraditional aspects of mathematical biology.

Modelling in Molecular Biology

2012-12-06 Science
Download Modelling in Molecular Biology PDF Online Free

Author :
Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 34X/5 ( reviews)

GET EBOOK


Book Synopsis Modelling in Molecular Biology by : Gabriel Ciobanu

Download or read book Modelling in Molecular Biology written by Gabriel Ciobanu. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Presents new mathematical and computational models as well as statistical methods for the solution of fundamental problems in the biosciences. Describes how to find regularities among empirical data, as well as conceptual models and theories.

You may also like...