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Modeling Neuropsychiatric Disorders in Laboratory Animals

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Release : 2015-08-28
Genre : Medical
Kind : eBook
Book Rating : 061/5 ( reviews)

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Book Synopsis Modeling Neuropsychiatric Disorders in Laboratory Animals by : Kurt Leroy Hoffman

Download or read book Modeling Neuropsychiatric Disorders in Laboratory Animals written by Kurt Leroy Hoffman. This book was released on 2015-08-28. Available in PDF, EPUB and Kindle. Book excerpt: Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease. Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research. Focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders Serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals Discusses specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders

Animal and Translational Models for CNS Drug Discovery: Neurological disorders

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Release : 2008
Genre : Animal models in research
Kind : eBook
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Book Synopsis Animal and Translational Models for CNS Drug Discovery: Neurological disorders by : Robert A. McArthur

Download or read book Animal and Translational Models for CNS Drug Discovery: Neurological disorders written by Robert A. McArthur. This book was released on 2008. Available in PDF, EPUB and Kindle. Book excerpt:

Animal Models in Medicine and Biology

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Release : 2020-04-08
Genre : Science
Kind : eBook
Book Rating : 115/5 ( reviews)

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Book Synopsis Animal Models in Medicine and Biology by : Eva Tvrdá

Download or read book Animal Models in Medicine and Biology written by Eva Tvrdá. This book was released on 2020-04-08. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to animal models, our knowledge of biology and medicine has increased enormously over the past decades, leading to significant breakthroughs that have had a direct impact on the prevention, management and treatment of a wide array of diseases.This book presents a comprehensive reference that reflects the latest scientific research being done in a variety of medical and biological fields utilizing animal models. Chapters on Drosophila, rat, pig, rabbit, and other animal models reflect frontier research in neurology, psychiatry, cardiology, musculoskeletal disorders, reproduction, chronic diseases, epidemiology, and pain and inflammation management. Animal Models in Medicine and Biology offers scientists, clinicians, researchers and students invaluable insights into a wide range of issues at the forefront of medical and biological progress.

Animal Models of Neurological Disease, II

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Release : 2013-08-11
Genre : Medical
Kind : eBook
Book Rating : 897/5 ( reviews)

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Book Synopsis Animal Models of Neurological Disease, II by : Alan A. Boulton

Download or read book Animal Models of Neurological Disease, II written by Alan A. Boulton. This book was released on 2013-08-11. Available in PDF, EPUB and Kindle. Book excerpt: to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface to these volumes in order to indicate why we think further - search using animals is necessary and why animal models of psychiatric disorders, in particular, are so important. We recognize that animals should only be used when suitable alternatives are not available. We think it self-e- dent, however, that humans can only be experimented upon in severely proscribed circumstances and alternative pro- dures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo processes. However, when the distress, discomfort, or pain to the animals outweighs the anticipated gains for human welfare, then the research is not ethical and should not be carried out. It is imperative that each individual researcher examine his/her own research from a critical moral standpoint - fore engaging in it, taking into consideration the animals’ welfare as well as the anticipated gains. Furthermore, once a decision to proceed with research is made, it is the researcher’s responsibility to ensure that the animals’ w- fare is of prime concern in terms of appropriate housing, feeding, and maximum reduction of any uncomfortable or distressing effects of the experimental conditions, and that these conditions undergo frequent formalized monitoring.

Animal Experimentation: Working Towards a Paradigm Change

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Release : 2019-04-30
Genre : Philosophy
Kind : eBook
Book Rating : 193/5 ( reviews)

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Book Synopsis Animal Experimentation: Working Towards a Paradigm Change by : Kathrin Herrmann

Download or read book Animal Experimentation: Working Towards a Paradigm Change written by Kathrin Herrmann. This book was released on 2019-04-30. Available in PDF, EPUB and Kindle. Book excerpt: Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

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