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Modeling for Prediction of Radiation-Induced Toxicity to Improve Therapeutic Ratio in the Modern Radiation Therapy Era

2021-07-27 Medical
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Release : 2021-07-27
Genre : Medical
Kind : eBook
Book Rating : 882/5 ( reviews)

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Book Synopsis Modeling for Prediction of Radiation-Induced Toxicity to Improve Therapeutic Ratio in the Modern Radiation Therapy Era by : Ester Orlandi

Download or read book Modeling for Prediction of Radiation-Induced Toxicity to Improve Therapeutic Ratio in the Modern Radiation Therapy Era written by Ester Orlandi. This book was released on 2021-07-27. Available in PDF, EPUB and Kindle. Book excerpt:

Modelling Radiotherapy Side Effects

2019-06-11 Science
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Release : 2019-06-11
Genre : Science
Kind : eBook
Book Rating : 105/5 ( reviews)

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Book Synopsis Modelling Radiotherapy Side Effects by : Tiziana Rancati

Download or read book Modelling Radiotherapy Side Effects written by Tiziana Rancati. This book was released on 2019-06-11. Available in PDF, EPUB and Kindle. Book excerpt: The treatment of a patient with radiation therapy is planned to find the optimal way to treat a tumour while minimizing the dose received by the surrounding normal tissues. In order to better exploit the possibilities of this process, the availability of accurate and quantitative knowledge of the peculiar responses of the different tissues is of paramount importance. This book provides an invaluable tutorial for radiation oncologists, medical physicists, and dosimetrists involved in the planning optimization phase of treatment. It presents a practical, accessible, and comprehensive summary of the field’s current research and knowledge regarding the response of normal tissues to radiation. This is the first comprehensive attempt to do so since the publication of the QUANTEC guidelines in 2010. Features: Addresses the lack of systemization in the field, providing educational materials on predictive models, including methods, tools, and the evaluation of uncertainties Collects the combined effects of features, other than dose, in predicting the risk of toxicity in radiation therapy Edited by two leading experts in the field

Machine Learning in Radiation Oncology

2015-06-19 Medical
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Release : 2015-06-19
Genre : Medical
Kind : eBook
Book Rating : 052/5 ( reviews)

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Book Synopsis Machine Learning in Radiation Oncology by : Issam El Naqa

Download or read book Machine Learning in Radiation Oncology written by Issam El Naqa. This book was released on 2015-06-19. Available in PDF, EPUB and Kindle. Book excerpt: ​This book provides a complete overview of the role of machine learning in radiation oncology and medical physics, covering basic theory, methods, and a variety of applications in medical physics and radiotherapy. An introductory section explains machine learning, reviews supervised and unsupervised learning methods, discusses performance evaluation, and summarizes potential applications in radiation oncology. Detailed individual sections are then devoted to the use of machine learning in quality assurance; computer-aided detection, including treatment planning and contouring; image-guided radiotherapy; respiratory motion management; and treatment response modeling and outcome prediction. The book will be invaluable for students and residents in medical physics and radiation oncology and will also appeal to more experienced practitioners and researchers and members of applied machine learning communities.

Stereotactic Body Radiation Therapy

2012-08-28 Medical
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Release : 2012-08-28
Genre : Medical
Kind : eBook
Book Rating : 04X/5 ( reviews)

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Book Synopsis Stereotactic Body Radiation Therapy by : Simon S. Lo

Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo. This book was released on 2012-08-28. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Molecular Targeted Radiosensitizers

2020-08-10 Medical
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Release : 2020-08-10
Genre : Medical
Kind : eBook
Book Rating : 011/5 ( reviews)

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Book Synopsis Molecular Targeted Radiosensitizers by : Henning Willers

Download or read book Molecular Targeted Radiosensitizers written by Henning Willers. This book was released on 2020-08-10. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.

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