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MicroRNA in Regenerative Medicine

2014-11-26 Science
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Release : 2014-11-26
Genre : Science
Kind : eBook
Book Rating : 582/5 ( reviews)

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Book Synopsis MicroRNA in Regenerative Medicine by : Chandan K. Sen

Download or read book MicroRNA in Regenerative Medicine written by Chandan K. Sen. This book was released on 2014-11-26. Available in PDF, EPUB and Kindle. Book excerpt: This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational application, they point to the current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA across repair and regeneration, and special coverage of methodologies and interventions as they point towards organ and tissue engineering Multi-colour text layout with 150 colour figures to illustrate important findings Take home messages encapsulate key lessons throughout text Short chapters offer focused discussion and clear ‘voice’

RNAi and MicroRNA-Mediated Gene Regulation in Stem Cells

2010-08-16 Medical
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Release : 2010-08-16
Genre : Medical
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis RNAi and MicroRNA-Mediated Gene Regulation in Stem Cells by : Baohong Zhang

Download or read book RNAi and MicroRNA-Mediated Gene Regulation in Stem Cells written by Baohong Zhang. This book was released on 2010-08-16. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.

Current Perspectives in microRNAs (miRNA)

2008-09-12 Medical
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Release : 2008-09-12
Genre : Medical
Kind : eBook
Book Rating : 338/5 ( reviews)

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Book Synopsis Current Perspectives in microRNAs (miRNA) by : Shao-Yao Ying

Download or read book Current Perspectives in microRNAs (miRNA) written by Shao-Yao Ying. This book was released on 2008-09-12. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17–25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. Currently over 1000 native miRNA species found in vertebrates and many more new miRNA homologs continue to be identified; however, most of their functions remain to be determined. In this book, many new perspectives of the miRNA research are reviewed and discussed, including their roles in stem cell maintenance, embryonic development, tissue differentiation, adult physiology, disease pathology, cancer research, viral infection, genetic engineering in plants, and utility in cosmetic applications. These new findings may not only provide significant insight into the various mechanisms of miRNAs but also offer a great opportunity in developing new therapeutic interventions.

MicroRNAs in Cancer Translational Research

2011-01-25 Medical
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Release : 2011-01-25
Genre : Medical
Kind : eBook
Book Rating : 981/5 ( reviews)

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Book Synopsis MicroRNAs in Cancer Translational Research by : William C.S. Cho

Download or read book MicroRNAs in Cancer Translational Research written by William C.S. Cho. This book was released on 2011-01-25. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNA (miRNA) is a cutting-edge topic in the scientific and medical fields. This is a timely and specialized book focusing on the current understanding of miRNAs and the potential for their application in cancer diagnosis, prognosis, and therapeutic targets. It also provides discussion of the lessons learned from translational miRNA studies and exploration of the next steps required to advance this field. The unique book comprises 22 in-depth chapters by gathering unparalleled topics of interest in miRNAs by international team of world-renowned experts in the field. The first fifteen chapters provide comprehensive and expert perspectives on the most common cancers from bench to bedside applications, there is no current book structured in this cancer-oriented way. The next seven chapters providing thorough overviews of miRNAs and cancer stem cells; miRNAs in cancer invasion and metastasis; miRNAs in predicting radiotherapy and chemotherapy response; as well as expounding the role of miRNA in anti-cancer drug resistance and as blood-based cancer biomarkers. Furthermore, this book explicates the interplay of miRNAs in cancer metabolism and an update on the pioneering RNAi-based treatment approaches is also presented. This specialized book will contribute great to the scientific and medical community by providing the up-to-date discoveries of miRNAs and their important roles in cancer translational research.

MicroRNA Profiling

2022-11-28 Science
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Release : 2022-11-28
Genre : Science
Kind : eBook
Book Rating : 232/5 ( reviews)

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Book Synopsis MicroRNA Profiling by : Sweta Rani

Download or read book MicroRNA Profiling written by Sweta Rani. This book was released on 2022-11-28. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides updated and comprehensive methods on miRNA biogenesis and their role in the development and progression of various human diseases. Chapters detail miRNA biogenesis, isolating RNA, extracellular vesicles (EVs), circulating miRNAs, analyzing miRNA and miRDeep-P2, protocols for total RNA isolation from cells, cell-derived products, isolation and characterization of exosomes, serum, plasma specimens, and software tools. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, MicroRNA Profiling: Methods and Protocols, Second Edition aims to provide comprehensive and accessible methods to undergraduate, graduate, and established scientist.

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