Share

Inflammation and the Microcirculation

2010 Medical
Download Inflammation and the Microcirculation PDF Online Free

Author :
Release : 2010
Genre : Medical
Kind : eBook
Book Rating : 656/5 ( reviews)

GET EBOOK


Book Synopsis Inflammation and the Microcirculation by : D. Neil Granger

Download or read book Inflammation and the Microcirculation written by D. Neil Granger. This book was released on 2010. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References

Microcirculation

2011-04-28 Science
Download Microcirculation PDF Online Free

Author :
Release : 2011-04-28
Genre : Science
Kind : eBook
Book Rating : 935/5 ( reviews)

GET EBOOK


Book Synopsis Microcirculation by : Ronald F. Tuma

Download or read book Microcirculation written by Ronald F. Tuma. This book was released on 2011-04-28. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a volume in the Handbook of Physiology, co-published with The American Physiological Society. Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. This volume pulls all of the critical information into one volume. Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume

Microcirculation

2012-12-02 Nature
Download Microcirculation PDF Online Free

Author :
Release : 2012-12-02
Genre : Nature
Kind : eBook
Book Rating : 499/5 ( reviews)

GET EBOOK


Book Synopsis Microcirculation by : Richard Effros

Download or read book Microcirculation written by Richard Effros. This book was released on 2012-12-02. Available in PDF, EPUB and Kindle. Book excerpt: Microcirculation: Current Physiologic, Medical, and Surgical Concepts is based primarily on a course and a series of lectures presented at a congress on microcirculation held at the University of California in August 1979. The book gives an overview of the concepts regarding the structure and properties of small vessels, a topic mostly read only in specialized journals. The primary focus of the text is on the function and dysfunction of small blood vessels. Three major parts comprise the text. Part I discusses the morphology, physiology, and pharmacology of circulation, and Part II presents the dynamics or role of the microcirculation in the study of diabetes. Finally, Part III discusses also the role of microcirculation in disease states, particularly hemoconcentration. The book will provide much information to researchers and students in the fields of biology, medicine, physiology, and pharmacology.

Basic and Clinical Understanding of Microcirculation

2020-07-22 Medical
Download Basic and Clinical Understanding of Microcirculation PDF Online Free

Author :
Release : 2020-07-22
Genre : Medical
Kind : eBook
Book Rating : 519/5 ( reviews)

GET EBOOK


Book Synopsis Basic and Clinical Understanding of Microcirculation by : Kaneez Fatima Shad

Download or read book Basic and Clinical Understanding of Microcirculation written by Kaneez Fatima Shad. This book was released on 2020-07-22. Available in PDF, EPUB and Kindle. Book excerpt: Microcirculation is key to providing enough nutrition and oxygen from head to toe. This is possible only through an extensive network of blood vessels spread around the body. Effect of microcirculation abnormalities stretch beyond one’s comprehension. The effects could be felt at any age, from the foetal life to the adulthood. The chapters present in this book describe how these abnormalities could lead to diseases such as atherosclerosis, thrombosis, diabetes, hypertension. Disorders of microcirculation could be related to the structural and/or functional damage to the inner lining of the blood vessels. Early identification of these disorders could benefit many ailments including cardiovascular and cerebrovascular diseases such as heart attack and stroke.

The Pathophysiology of the Microcirculation

1994-02-28 Medical
Download The Pathophysiology of the Microcirculation PDF Online Free

Author :
Release : 1994-02-28
Genre : Medical
Kind : eBook
Book Rating : 470/5 ( reviews)

GET EBOOK


Book Synopsis The Pathophysiology of the Microcirculation by : Nicholas A. Mortillaro

Download or read book The Pathophysiology of the Microcirculation written by Nicholas A. Mortillaro. This book was released on 1994-02-28. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the pathophysiology of the microcirculation, an intensely studied area of the circulatory system. Featuring contributions from 29 top investigators in the field, the book begins with an introduction to the general structure of the normal microvascular system, with special emphasis on the characteristics of blood vessel segments collectively comprising the system. Significant areas covered in the book include angiogenesis, neoplasias, hypertension, shock, ischemia/reperfusion, diabetes, immunologic injury, and thermal injury. It also covers the effects of aging and environmental factors on the microcirculation-topics not often examined in depth. More than 80 figures and tables illustrate key concepts throughout the book.

You may also like...