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Metabolic Engineering for Bioactive Compounds

2017-10-07 Medical
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Release : 2017-10-07
Genre : Medical
Kind : eBook
Book Rating : 114/5 ( reviews)

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Book Synopsis Metabolic Engineering for Bioactive Compounds by : Vipin Chandra Kalia

Download or read book Metabolic Engineering for Bioactive Compounds written by Vipin Chandra Kalia. This book was released on 2017-10-07. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively discusses the latest research in the area of metabolic engineering. Metabolic engineering solutions for bioactive compounds are now being derived by means of heterologous gene expression, in a wide range of organisms. The book provides an overview of the model systems being employed for metabolic manipulation to yield bioactive molecules, such as single-cell proteins, antibody generation, metabolites, proteases, chaperones, therapeutic proteins, nanomaterials, polymeric conjugates, dendrimers and nanoassemblies, Escherichia coli, Agrobacterium, Saccharomyces cerevisiae and cell lines, etc. In addition, it shares insights into the scope of these methods in the areas of prevention, diagnosis and treatment of diseases, e.g. immunotherapy for curing various diseases like cancer, allergies, autoimmune diseases, etc.

Recent Advances in Application of Synthetic Biology for Production of Bioactive Compounds

2022-02-09 Science
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Release : 2022-02-09
Genre : Science
Kind : eBook
Book Rating : 098/5 ( reviews)

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Book Synopsis Recent Advances in Application of Synthetic Biology for Production of Bioactive Compounds by : Luan Luong Chu

Download or read book Recent Advances in Application of Synthetic Biology for Production of Bioactive Compounds written by Luan Luong Chu. This book was released on 2022-02-09. Available in PDF, EPUB and Kindle. Book excerpt:

Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds

2024-03-01 Science
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Release : 2024-03-01
Genre : Science
Kind : eBook
Book Rating : 593/5 ( reviews)

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Book Synopsis Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds by : Yongjun Wei

Download or read book Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds written by Yongjun Wei. This book was released on 2024-03-01. Available in PDF, EPUB and Kindle. Book excerpt: Many plant-derived bioactive compounds are the foundation effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limits their application in drugs and other industries. With the development of synthetic biology and green biomanufacturing, the biosynthesis of complex bioactive compounds is possible. However, the engineering fundamentals for microbial biosynthetic of plant-derived bioactive compounds is vast. Engineering biology for microbial biosynthesis of plant-derived bioactive compounds summarizes the engineering fundamental biotechnologies for microbial production of plant-derived bioactive compounds, allowing this content to be easily accessed. Coverage includes summaries of key achievements, identification of challenges, current approaches, tips and tricks, and helpful insights into critical bottlenecks. With a comprehensive coverage of the field, Engineering biology for microbial biosynthesis of plant-derived bioactive compounds is of great interest to undergraduate and graduate students, scientists, researchers as well as engineers who work on the microbial production of plant-derived bioactive compounds. - Provides valuable information for engineers, scientists, and industrial researchers who want to obtain microbial strains with the ability of plant-derived bioactive compound production - Guides microbial production of plant-derived bioactive compounds at the laboratory and industrial levels - Ideal resource for anyone who works on the microbial production of plant-derived bioactive compounds

Natural Products

2022
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Release : 2022
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Natural Products by : Danielle Yee

Download or read book Natural Products written by Danielle Yee. This book was released on 2022. Available in PDF, EPUB and Kindle. Book excerpt: Natural products from plants, fungi, and bacteria are an invaluable source of bioactive compounds with numerous applications in the pharmaceutical industry and agriculture. Metabolic engineering can be utilized to increase the yield of these valuable compounds and their precursors. Meanwhile, genome mining can be employed to discover novel natural product scaffolds and unique functional groups that can confer various biological activities to the resulting compound. During my doctoral research, I have performed work in both of these fields to engineer yeast for precursor production of the pharmaceutically relevant monoterpene indole alkaloids as well as elucidate the biosynthesis of new natural products from several fungal species. Strategies for yeast metabolic engineering included targeting the production of monoterpene precursors to the mitochondria and further mitochondrial engineering through deletion of transporter genes and transcription factor overexpression. Genome mining efforts led to the discovery of new compounds with a unique hybrid terpene and amino acid derived scaffold as well as a new family of biosynthetic core genes that form arginine containing cyclodipeptides. Study of these pathways also resulted in the identification of enzymes that can perform novel reactions to create greater chemical diversity. These genes can expand the query database to mine for more compounds with novel structures.

Microbial Bioactive Compounds

2023-12-29 Science
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Release : 2023-12-29
Genre : Science
Kind : eBook
Book Rating : 828/5 ( reviews)

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Book Synopsis Microbial Bioactive Compounds by : Ravindra Soni

Download or read book Microbial Bioactive Compounds written by Ravindra Soni. This book was released on 2023-12-29. Available in PDF, EPUB and Kindle. Book excerpt: This book delves into microbial production and its implications for various industries and presents the latest advancements in the field of bioactive compound production by microorganisms. Divided into 16 chapters, the book covers a wide range of topics, starting with the emerging trends in microbial production techniques, followed by the potential of fungi and algae in producing bioactive compounds, and the applications of bioactive compounds in medicine, agriculture, and industry. Contributions from expert scientists emphasize the significance of metabolic engineering and modern analytical techniques for the extraction, purification, and structural characterization of microbial bioactive compounds. The authors also present alternative technologies and methodologies for the recovery and extraction of these compounds from microbial sources and highlight the health-promoting benefits of natural plant-derived bioactive compounds. Particular attention is given to nanocarriers and their potential for managing the delivery of bioactive compounds in therapeutic applications. The importance of actinomycetes and their bioactive potential in the agricultural sector is also discussed. In this book, readers will also find out about the importance of microbial community dynamics in Antarctica, their ecological potential, and their industrial application. The last chapter of the book offers an industrial perspective of microbial pigments and their applications. This book is a valuable resource for researchers, academics, and industry professionals seeking to understand and harness the potential of microbial bioactive compounds for sustainable development, industrial applications, and improved human well-being.

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