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Mass Spectrometry in the Biological Sciences

2012-12-06 Science
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Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 299/5 ( reviews)

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Book Synopsis Mass Spectrometry in the Biological Sciences by : A. L. Burlingame

Download or read book Mass Spectrometry in the Biological Sciences written by A. L. Burlingame. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Leading practitioners describe in detail advanced methods of mass spectrometry used in structural characterization of biomacromolecules of both natural and recombinant origin. They demonstrate by example how these methodologies can solve a wide array of real-world problems in protein biochemistry, immunology, and glycobiology, as well as for human bacterial pathogens, lipids, and nucleic acids. The book offers a unique opportunity to learn these techniques that are revolutionizing the field. Its authoritative assessment in the context of how to solve important and challenging problems in bioscience and medicine ensures a competitive advantage for today's researchers.

Mass Spectrometry in the Biological Sciences: A Tutorial

2012-12-06 Science
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Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 186/5 ( reviews)

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Book Synopsis Mass Spectrometry in the Biological Sciences: A Tutorial by : M.L Gross

Download or read book Mass Spectrometry in the Biological Sciences: A Tutorial written by M.L Gross. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: The developments in mass spectrometry over the past fifteen years have been impressive in their implications in bioanalytical chemistry. The achievements begin with the inventions of Cf-252 Plasma Desorption Mass Spectrometry by Macfarlane and Fourier Transform Mass Spectrometry by Comisarow and Marshall in the mid 1970s. The former showed the feasibility of producing large gas-phase ions from large biomolecules whereas the latter enhanced the capabilities for ion trapping especially in analytical mass spectrometry. A major achievement was the development by Barber of Fast Atom Bombardment (FAB) mass spectrometry, an advance that heralded a new era in biological mass spectrometry. Contemporary and routine instruments such as magnetic sectors and quadrupoles were rapidly adapted to F AB, and nearly the entire universe of small molecules became amenable to study by mass spectrometry. The introduction of FAB also paved the way for improvement of instrument capability. For example, the upper mass limit of magnet sector mass spectrometers was increased by nearly an order of magnitude by the instrument manufacturers. Furthermore, the technique of tandem mass spectrometry (MS/MS) was given new meaning because important structural information for biomolecules could now be produced for ions introduced by FAB into the tandem instrument. The evolution of MS/MS continues today with the development of ion traps, time-of-flight, and sector instruments equipped with array detection.

Mass Spectrometry of Biological Materials, Second Edition

1998-03-02 Science
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Release : 1998-03-02
Genre : Science
Kind : eBook
Book Rating : 574/5 ( reviews)

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Book Synopsis Mass Spectrometry of Biological Materials, Second Edition by : Barbara S. Larsen

Download or read book Mass Spectrometry of Biological Materials, Second Edition written by Barbara S. Larsen. This book was released on 1998-03-02. Available in PDF, EPUB and Kindle. Book excerpt: Second Edition provides up-to-the-minute discussions on the application of mass spectrometry to the biological sciences. Shows how and why experiments are performed and furnishes details to facilitate duplication of results.

Spectroscopy for the Biological Sciences

2005-08-19 Science
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Release : 2005-08-19
Genre : Science
Kind : eBook
Book Rating : 547/5 ( reviews)

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Book Synopsis Spectroscopy for the Biological Sciences by : Gordon G. Hammes

Download or read book Spectroscopy for the Biological Sciences written by Gordon G. Hammes. This book was released on 2005-08-19. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the physical principles of spectroscopy and their applications to the biological sciences Advances in such fields as proteomics and genomics place new demands on students and professionals to be able to apply quantitative concepts to the biological phenomena that they are studying. Spectroscopy for the Biological Sciences provides students and professionals with a working knowledge of the physical chemical aspects of spectroscopy, along with their applications to important biological problems. Designed as a companion to Professor Hammes's Thermodynamics and Kinetics for the Biological Sciences, this approachable yet thorough text covers the basic principles of spectroscopy, including: * Fundamentals of spectroscopy * Electronic spectra * Circular dichroism and optical rotary dispersion * Vibration in macromolecules (IR, Raman, etc.) * Magnetic resonance * X-ray crystallography * Mass spectrometry With a minimum of mathematics and a strong focus on applications to biology, this book will prepare current and future professionals to better understand the quantitative interpretation of biological phenomena and to utilize these tools in their work.

Mass Spectrometry in Biomolecular Sciences

2012-12-06 Science
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Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 174/5 ( reviews)

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Book Synopsis Mass Spectrometry in Biomolecular Sciences by : Richard M. Caprioli

Download or read book Mass Spectrometry in Biomolecular Sciences written by Richard M. Caprioli. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry in the Biological Sciences covers the most recent technological and applied developments in the area, including both ionization techniques and ion analysis. It introduces and reviews some of the newer ionization methods, describes the major instrumentation involved in mass analysis, and presents the scope of the technology in biology, medicine, and environmental science. Specific examples are given for a number of topics. It also deals with recent achievements in the on-line combination of separation techniques such as gas chromatography, liquid chromatography, and supercritical fluid technology.

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