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Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

2017-03-09 Medical
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Release : 2017-03-09
Genre : Medical
Kind : eBook
Book Rating : 810/5 ( reviews)

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Book Synopsis Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease by : Venkataramana K Sidhaye

Download or read book Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease written by Venkataramana K Sidhaye. This book was released on 2017-03-09. Available in PDF, EPUB and Kindle. Book excerpt: Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences

Lung Epithelial Biology: Pathogenesis and Treatment of Pulmonary Diseases

2023-09-26 Health & Fitness
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Release : 2023-09-26
Genre : Health & Fitness
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Lung Epithelial Biology: Pathogenesis and Treatment of Pulmonary Diseases by : Tabatha Colby

Download or read book Lung Epithelial Biology: Pathogenesis and Treatment of Pulmonary Diseases written by Tabatha Colby. This book was released on 2023-09-26. Available in PDF, EPUB and Kindle. Book excerpt: Lung epithelial biology is focused on the study of epithelial cells present in the lungs. These cells are located in the interface between the organism and the environment, and perform various significant functions like fluid balance, barrier protection, surfactant and mucus production, as well as inducing immune responses. The respiratory epithelium acts as a functional and physical barrier responsible for safeguarding against infectious agents. The alveolar surface is stacked with membranous pneumocytes called granular pneumocytes, type I alveolar epithelial cells (AEC I) and type II alveolar epithelial cells (AEC II). AEC I are thin, squamous and large cells that contribute in gaseous exchange. These cells also create a barrier to detect microbial products for initiating inflammatory responses. AEC II are cuboidal cells responsible for epithelium reparation upon injury and ion transport. These are also involved in lung defense through the secretion of antimicrobial products, like complement, lysozyme, and surfactant proteins (SP). This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the study of lung epithelial biology. Researchers and students engaged in the treatment of pulmonary diseases will be assisted by it.

Lung Biology and Pathophysiology

2024-02-20 Medical
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Release : 2024-02-20
Genre : Medical
Kind : eBook
Book Rating : 284/5 ( reviews)

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Book Synopsis Lung Biology and Pathophysiology by : Yutong Zhao

Download or read book Lung Biology and Pathophysiology written by Yutong Zhao. This book was released on 2024-02-20. Available in PDF, EPUB and Kindle. Book excerpt: The lungs are the organ for gas exchange between the body and the external environment. Dysfunction of upper airway epithelium and smooth muscle cells leads to pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions, resulting in airway inflammation and narrowing. Injury to alveolar epithelium and endothelium causes influx of neutrophil and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. In addition to lung structural cells, immune cells, including alveolar macrophages and lymphocytes play critical roles in the maintenance of lung function. This book contributes to the understanding homeostasis of lung cells in the physiological and pathological conditions critical to the development of novel therapeutics. Key Features Highlights the role the lungs play as an interface between the body and the environment Describes the underlying mechanism of lung diseases Emphasizes the ways nutrition contributes to lung health as well as the ways pollution adversely affect lung function Includes contributions from leading researchers Chapters 8 and 13 of this book are available for free in PDF format as Open Access from the individual product page at www.routledge.com. It has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.

How Tobacco Smoke Causes Disease

2010 Government publications
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Release : 2010
Genre : Government publications
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General. This book was released on 2010. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

The Pulmonary Epithelium in Health and Disease

2008-04-30 Science
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Release : 2008-04-30
Genre : Science
Kind : eBook
Book Rating : 003/5 ( reviews)

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Book Synopsis The Pulmonary Epithelium in Health and Disease by : David Proud

Download or read book The Pulmonary Epithelium in Health and Disease written by David Proud. This book was released on 2008-04-30. Available in PDF, EPUB and Kindle. Book excerpt: "This is essential reading for everyone who would like to update their knowledge of the pulmonary epithelium. It offers a comparison between laboratory animal models and human lungs, highlighting the differences and the similarities between the two, which will be particularly useful to researchers." –Doody's, April 2009 The past two decades have seen extraordinary advances in our understanding of the role of the pulmonary epithelium in airway health and disease. Our understanding of epithelial biology has expanded exponentially in the past decade. This book provides a unique comprehensive description of the structure of the epithelium, its damage by various agents and the mechanism of epithelial repair. In addition, it's detailed coverage includes not only the multiple ways in which the epithelium contributes to host defence, but also the nature and functional consequences of the interactions of inhaled pathogens, including viruses, bacteria, allergens and pollutants. the role of the epithelium in regulating airway inflammation and structure is also discussed, as is the role of the epithelium as a target for inhaled medications and as a route for novel drug delivery. Containing chapters on multiple aspects of epithelial function in health and disease, each one is written by a leader in the field. This is essential reading for pulmonary researchers and physicians requiring detailed advanced understanding of the epithelium as well as those working in allergy, biomedical and pharmaceutical research.

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