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Lecture Notes On Computational Structural Biology

2008-06-11 Science
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Release : 2008-06-11
Genre : Science
Kind : eBook
Book Rating : 750/5 ( reviews)

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Book Synopsis Lecture Notes On Computational Structural Biology by : Zhijun Wu

Download or read book Lecture Notes On Computational Structural Biology written by Zhijun Wu. This book was released on 2008-06-11. Available in PDF, EPUB and Kindle. Book excerpt: While the field of computational structural biology or structural bioinformatics is rapidly developing, there are few books with a relatively complete coverage of such diverse research subjects studied in the field as X-ray crystallography computing, NMR structure determination, potential energy minimization, dynamics simulation, and knowledge-based modeling. This book helps fill the gap by providing such a survey on all the related subjects. Comprising a collection of lecture notes for a computational structural biology course for the Program on Bioinformatics and Computational Biology at Iowa State University, the book is in essence a comprehensive summary of computational structural biology based on the author's own extensive research experience, and a review of the subject from the perspective of a computer scientist or applied mathematician. Readers will gain a deeper appreciation of the biological importance and mathematical novelty of the research in the field.

Lecture Notes on Computational Structural Biology

2008 Science
Download Lecture Notes on Computational Structural Biology PDF Online Free

Author :
Release : 2008
Genre : Science
Kind : eBook
Book Rating : 787/5 ( reviews)

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Book Synopsis Lecture Notes on Computational Structural Biology by : Zhijun Wu

Download or read book Lecture Notes on Computational Structural Biology written by Zhijun Wu. This book was released on 2008. Available in PDF, EPUB and Kindle. Book excerpt: 1. Introduction. 1.1. Protein structure. 1.2. Structure determination. 1.3. Dynamics simulation. 1.4. The myth of protein folding -- 2. X-ray crystallography computing. 2.1. The phase problem. 2.2. Least squares solutions. 2.3. Entropy maximization. 2.4. Indirect methods -- 3. NMR structure determination. 3.1. Nuclear magnetic resonance. 3.2. Distance geometry. 3.3. Distance-based modeling. 3.4. Structural analysis -- 4. Potential energy minimization. 4.1. Potential energy function. 4.2. Local optimization. 4.3. Global optimization. 4.4. Energy transformation -- 5. Molecular dynamics simulation. 5.1. Equations of motion. 5.2. Initial-value problem. 5.3. Boundary-value problem. 5.4. Normal mode analysis -- 6. Knowledge-based protein modeling. 6.1. Sequence/structural alignment. 6.2. Fold recognition/inverse folding. 6.3. Knowledge-based structural refinement. 6.4. Structural computing and beyond

Basics of Bioinformatics

2013-11-26 Computers
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Release : 2013-11-26
Genre : Computers
Kind : eBook
Book Rating : 511/5 ( reviews)

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Book Synopsis Basics of Bioinformatics by : Rui Jiang

Download or read book Basics of Bioinformatics written by Rui Jiang. This book was released on 2013-11-26. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate Statistical Methods in Bioinformatics Research, Association Analysis for Human Diseases: Methods and Examples, Data Mining and Knowledge Discovery Methods with Case Examples, Applied Bioinformatics Tools, Foundations for the Study of Structure and Function of Proteins, Computational Systems Biology Approaches for Deciphering Traditional Chinese Medicine, and Advanced Topics in Bioinformatics and Computational Biology. This book can serve as not only a primer for beginners in bioinformatics, but also a highly summarized yet systematic reference book for researchers in this field. Rui Jiang and Xuegong Zhang are both professors at the Department of Automation, Tsinghua University, China. Professor Michael Q. Zhang works at the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.

Computational Structural Biology

2008 Science
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Release : 2008
Genre : Science
Kind : eBook
Book Rating : 780/5 ( reviews)

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Book Synopsis Computational Structural Biology by : Torsten Schwede

Download or read book Computational Structural Biology written by Torsten Schwede. This book was released on 2008. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive introduction to Landau-Lifshitz equations and Landau-Lifshitz-Maxwell equations, beginning with the work by Yulin Zhou and Boling Guo in the early 1980s and including most of the work done by this Chinese group led by Zhou and Guo since. The book focuses on aspects such as the existence of weak solutions in multi dimensions, existence and uniqueness of smooth solutions in one dimension, relations with harmonic map heat flows, partial regularity and long time behaviors. The book is a valuable reference book for those who are interested in partial differential equations, geometric analysis and mathematical physics. It may also be used as an advanced textbook by graduate students in these fields.

Transactions on Computational Systems Biology VI

2006-11-27 Computers
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Release : 2006-11-27
Genre : Computers
Kind : eBook
Book Rating : 798/5 ( reviews)

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Book Synopsis Transactions on Computational Systems Biology VI by : Gordon Plotkin

Download or read book Transactions on Computational Systems Biology VI written by Gordon Plotkin. This book was released on 2006-11-27. Available in PDF, EPUB and Kindle. Book excerpt: The 5th Transactions on Computational Systems Biology volume, edited by Gordon Plotkin, features carefully selected and enhanced contributions initially presented at the 2005 IEEE International Conference on Granular Computing. The 9 papers selected for this special issue discuss various aspects of computational methods, algorithm and techniques in bioinformatics such as gene expression analysis, biomedical literature mining and natural language processing, protein structure prediction, biological database management and biomedical information retrieval.

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