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In Silico Technologies in Drug Target Identification and Validation

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Author :
Release : 2006
Genre : Drug development
Kind : eBook
Book Rating : 395/5 ( reviews)

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Book Synopsis In Silico Technologies in Drug Target Identification and Validation by : Darryl Leon

Download or read book In Silico Technologies in Drug Target Identification and Validation written by Darryl Leon. This book was released on 2006. Available in PDF, EPUB and Kindle. Book excerpt:

In Silico Technologies in Drug Target Identification and Validation

Download In Silico Technologies in Drug Target Identification and Validation PDF Online Free

Author :
Release : 2006-06-13
Genre : Medical
Kind : eBook
Book Rating : 737/5 ( reviews)

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Book Synopsis In Silico Technologies in Drug Target Identification and Validation by : Darryl Leon

Download or read book In Silico Technologies in Drug Target Identification and Validation written by Darryl Leon. This book was released on 2006-06-13. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry relies on numerous well-designed experiments involving high-throughput techniques and in silico approaches to analyze potential drug targets. These in silico methods are often predictive, yielding faster and less expensive analyses than traditional in vivo or in vitro procedures. In Silico Technologies in Drug Target Ide

Target Identification and Validation in Drug Discovery

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Author :
Release : 2019-04-12
Genre : Medical
Kind : eBook
Book Rating : 440/5 ( reviews)

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Book Synopsis Target Identification and Validation in Drug Discovery by : Jürgen Moll

Download or read book Target Identification and Validation in Drug Discovery written by Jürgen Moll. This book was released on 2019-04-12. Available in PDF, EPUB and Kindle. Book excerpt: This second edition book explores breakthrough technologies in the field of drug target identification and validation. The volume emphasizes particularly revolutionary technologies, such as CRISPR-related screening, “big data,” and in silico approaches, as well as in vivo applications of CRISPR and best uses of animal models in drug development. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Fully updated and authoritative, Target Identification and Validation in Drug Discovery: Methods and Protocols, Second Edition is an ideal guide for molecular and cellular biologists, pharmacologists, pathologists, bioinformaticians, clinical researchers, or investigators, as well as experts in other fields that need a quick overview of these state-of-the-art technologies.

Target Discovery and Validation

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Author :
Release : 2020-02-18
Genre : Medical
Kind : eBook
Book Rating : 299/5 ( reviews)

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Book Synopsis Target Discovery and Validation by : Alleyn T. Plowright

Download or read book Target Discovery and Validation written by Alleyn T. Plowright. This book was released on 2020-02-18. Available in PDF, EPUB and Kindle. Book excerpt: The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Throughout, the authors highlight a range of diverse approaches, and target validation studies reveal how these methods can support academic and drug discovery scientists in their target discovery and validation research. This resource: -Offers a guide to identifying and validating targets, a key enabling technology without which no new drug development is possible -Presents the information needed for choosing the appropriate assay method from the ever-growing range of available options -Provides practical examples from recent drug development projects, e. g. in kinase inhibitor profiling Written for medicinal chemists, pharmaceutical professionals, biochemists, biotechnology professionals, and pharmaceutical chemists, Target Discovery and Validation explores the current methods for the identification and validation of drug targets in one comrpehensive volume. It also includes numerous practical examples.

Drug Target Selection and Validation

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Release : 2022-05-17
Genre : Medical
Kind : eBook
Book Rating : 957/5 ( reviews)

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Book Synopsis Drug Target Selection and Validation by : Marcus T. Scotti

Download or read book Drug Target Selection and Validation written by Marcus T. Scotti. This book was released on 2022-05-17. Available in PDF, EPUB and Kindle. Book excerpt: The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.

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