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In Quest of Tomorrow's Medicines

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Release : 2003-01-14
Genre : Business & Economics
Kind : eBook
Book Rating : 421/5 ( reviews)

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Book Synopsis In Quest of Tomorrow's Medicines by : Jürgen Drews

Download or read book In Quest of Tomorrow's Medicines written by Jürgen Drews. This book was released on 2003-01-14. Available in PDF, EPUB and Kindle. Book excerpt: An eminent scientist talks about the pharmaceutical industry, biotechnology and the future of drug research. In the course of our busy, technologically-driven lives, it is taken for granted that we respond to minor fluctuations in our health by taking pills -- pills for headache and for toothache; sleeping pills and tranquilizers; pills to lower fever, quiet coughs, and clear the sinuses; medicines to reduce appetite; preparations to relieve heartburn; and many more. In the war against serious disease, medicines are an indispensable weapon in the physician's arsenal: they save lives, or at least prolong them and make them more bearable. Despite the important role that pharmaceuticals play in our lives, few of us know where medicines come from or how the pharmaceutical industry discovers and develops new drugs. Jurgen Drews, an acclaimed leader in the pharmaceutical industry, tells the fascinating story of drug discovery and development from his years of successfully leading internatnional research teams at Hoffman-LaRoche. Drews traces the history of modern drug development from pharmacies, chemical companies, and individual entrepeneurs in Switzerland, Germany and the U.S. to the mega-corporations that dot the landscape of Europe, Japan and America. He describes the process by which new drugs are tested and brought to market, including a provacative look at how AIDS activism stimulated the approval process in the US. Drews' commentary on the role of clinical trials -- the time involved and their cost -- is sobering testimony to the complexity of bringing innovation to the marketplace. In the final two chapters of "In Quest of Tomorrow's Medicines", Drews offers an important and critical analysis of research in the the pharmaceutical industry, pointing to strategies that work and management practices that impede progress. Drews' comments on the impact that the growing relationship between the biotechnology industry and university-sponsored research will have ont he pharmaceutical industry makes provocative reading for pharmaceutical researchers, managers and investors. "In Quest of Tomorrow's Medicines" in written in clear, thoughtful language for people in the pharmaceutical and biotechnology industries, as well as policy makers, industry analysts and observers.

In Quest of Tomorrow's Medicines

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Author :
Release : 2012-11-26
Genre :
Kind : eBook
Book Rating : 052/5 ( reviews)

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Book Synopsis In Quest of Tomorrow's Medicines by :

Download or read book In Quest of Tomorrow's Medicines written by . This book was released on 2012-11-26. Available in PDF, EPUB and Kindle. Book excerpt:

Tomorrow's Medicine

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Author :
Release : 2014-04-28
Genre : Medical
Kind : eBook
Book Rating : 877/5 ( reviews)

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Book Synopsis Tomorrow's Medicine by : Scientific American Editors

Download or read book Tomorrow's Medicine written by Scientific American Editors. This book was released on 2014-04-28. Available in PDF, EPUB and Kindle. Book excerpt: One hundred years ago, most of the medical treatments and technologies that we take for granted hadn't even been imagined or were found in the pages of science fiction novels rather than medical journals. Today, on the other hand, medical research often sounds like science fiction. This eBook, Tomorrow's Medicine, looks at some of the more fascinating areas where technology that could transform health is being developed, including cybernetics, regenerative medicine, nanotechnology and genetically tailored treatments. Although many of these advances may not be ready to treat humans for many years, some of them may someday profoundly change—and extend—our lives. In "Bionic Connections," for example, D. Kacy Cullen and Douglas Smith discuss synthetic limbs that function as well (or better) than our own. Echoes of the 1966 film Fantastic Voyage abound in "Nanomedicine Targets Cancer" by James Heath, Mark Davis and Leroy Hood, who examine how miniaturized tools can both measure the molecular interactions of disease and deliver targeted therapies. Several articles discuss different approaches for regeneration, including "Grow Your Own Eye," in which author Yoshiki Sasai illustrates how his lab successfully grew a retina from stem cells to "A Sweet Solution for Replacing Organs," in which Katherine Harmon describes how a speaker at a recent TED talk used a 3-D printer to create a kidney. A century from now, will the sight of an amputee be a rarity, with cybernetic limbs controlled by thought and nearly indistinguishable from the biological ones? Perhaps most people will have their genomes read for indications of future disease and take steps to prevent it – or even to cure inherited disorders. Will we replace some drugs with tiny machines, fanning out inside the body to repair damage? As exciting as these possibilities are to extend both the length and quality of life, immortality – or at least agelessness – may be forever out of our reach. As Thomas Kirkwood notes in his piece, "Why Can't We Live Forever?" death might be the price we pay for our complex biology. Even so, the doctors of a century past would surely be impressed by what medical science has accomplished in the past hundred years: antibiotics, organ transplants and the elimination of smallpox, to name but a few. The next century should be equally impressive, and with the various types of new technologies on the horizon, many of us have a good chance of seeing it happen.

Real World Drug Discovery

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Release : 2010-07-07
Genre : Medical
Kind : eBook
Book Rating : 888/5 ( reviews)

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Book Synopsis Real World Drug Discovery by : Robert M. Rydzewski

Download or read book Real World Drug Discovery written by Robert M. Rydzewski. This book was released on 2010-07-07. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery increasingly requires a common understanding by researchers of the many and diverse factors that go into the making of new medicines. The scientist entering the field will immediately face important issues for which his education may not have prepared him: project teams, patent law, consultants, target product profiles, industry trends, Gantt charts, target validation, pharmacokinetics, proteomics, phenotype assays, biomarkers, and many other unfamiliar topics for which a basic understanding must somehow be obtained. Even the more experienced scientist can find it frustratingly difficult to get an overview of the many factors involved in modern drug discovery and often only after years of exploring does a whole and integrated picture emerge in the mind of the researcher.Real World Drug Discovery: A Chemist's Guide to Biotech and Pharmaceutical Research presents this kind of map of the landscape of drug discovery. In a single, readable volume it outlines processes and explains essential concepts and terms for the recent science graduate wondering what to expect in pharma or biotech, the medicinal chemist seeking a broader and more timely understanding of the industry, or the contractor or collaborator whose understanding of the commercial drug discovery process could increase the value of his contribution to it. - Interviews with well-known experts in many of the fields involved, giving insightful comments from authorities on many of the sub-disciplines important to cutting edge drug discovery. - Helpful suggestions gleaned from years of experience in biotech and pharma, which represents a repository drug discovery "lore" not previously available in any book. - "Periodic Table of Drugs" listing current top-selling drugs arranged by target and laid out so that structural similarities and differences are plain and clear. - Extensive use of diagrams to illustrate concepts like biotech startup models, preteomic profiling for target identification, Gantt charts for project planning, etc.

An Introduction to Medicinal Chemistry

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Author :
Release : 2017
Genre : Science
Kind : eBook
Book Rating : 694/5 ( reviews)

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Book Synopsis An Introduction to Medicinal Chemistry by : Graham L. Patrick

Download or read book An Introduction to Medicinal Chemistry written by Graham L. Patrick. This book was released on 2017. Available in PDF, EPUB and Kindle. Book excerpt: For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market? An Introduction to Medicinal Chemistry, sixth edition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Part one of the book introduces the principles of drug action via targets such as receptors and enzymes. The book goes on to explore how drugs work at the molecular level (pharmacodynamics), and the processes involved in ensuring a drug meets its target (pharmacokinetics). Further sections cover the processes by which drugs are discovered and designed, and what has to happen before a drug can be made available to the public. The book concludes with a selection of current topics in medicinal chemistry, and a discussion of various key drug groups. The subject is brought to life throughout by engaging case studies highlighting particular drugs and the stories behind their discovery and development. The Online Resource Centre features: For students: DT Multiple Choice Questions to support self-directed learning DT Web articles describing recent developments in the field and further information on topics covered in the book DT Journal Club to encourage students to critically analyse the research literature DT Molecular Modelling Exercises, with new exercises in Chem3D DT New assignments to help students develop data analysis and problem solving skills For registered adopters of the book: DT A test bank of additional multiple-choice questions, with links to relevant sections in the book DT Answers to end-of-chapter questions. DT Figures from the book, ready to download. DT Power Point slides to accompany every chapter in the book.

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