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Improving Clinical Trials in the Critically Ill

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Release : 2009
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Improving Clinical Trials in the Critically Ill by : Jean-Paul Mira

Download or read book Improving Clinical Trials in the Critically Ill written by Jean-Paul Mira. This book was released on 2009. Available in PDF, EPUB and Kindle. Book excerpt:

50 Studies Every Intensivist Should Know

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Author :
Release : 2018
Genre : Medical
Kind : eBook
Book Rating : 657/5 ( reviews)

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Book Synopsis 50 Studies Every Intensivist Should Know by : Edward A. Bittner

Download or read book 50 Studies Every Intensivist Should Know written by Edward A. Bittner. This book was released on 2018. Available in PDF, EPUB and Kindle. Book excerpt: This title presents key studies that have shaped the practice of critical care medicine. Selected using a rigorous methodology, the studies cover topics including: sedation and analgesia, resuscitation, shock, ARDS, nutrition, renal failure, trauma, infection, diabetes, and physical therapy

Evaluating Critical Care

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Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 193/5 ( reviews)

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Book Synopsis Evaluating Critical Care by : William J. Sibbald

Download or read book Evaluating Critical Care written by William J. Sibbald. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Measuring the quality of a complex service like critical care that combines the highest technology with the most intimate caring is a challenge. Recently, con sumers, clinicians, and payers have requested more formal assessments and comparisons of the quality and costs of medical care [2). Donabedian [1) pro posed a framework for thinking about the quality of medical care that separates quality into three components: structure, process, and outcome. An instructive analogy for understanding this framework is to imagine a food critic evaluating the quality of a restaurant. The critic might comment on the decoration and lighting ofthe restaurant, how close the tables are to each other, the extent ofthe wine list and where the chef trained. These are all evaluations of the restaurant structure. In addition, the critic might comment on whether the service was courteous and timely - measures of process. Finally, the critic might comment on outcomes like customer satisfaction or food poisoning. Similarly, to a health care critic, structure is the physical and human resources used to deliver medi cal care. Processes are the actual treatments offered to patients. Finally,outcomes are what happens to patients, for example, mortality, quality of life,and satisfac tion with care (Table 1). There is a debate about which of these measurements is the most important measure of quality.

Small Clinical Trials

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Release : 2001-01-01
Genre : Medical
Kind : eBook
Book Rating : 148/5 ( reviews)

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Book Synopsis Small Clinical Trials by : Institute of Medicine

Download or read book Small Clinical Trials written by Institute of Medicine. This book was released on 2001-01-01. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies

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Release : 2019-10-17
Genre :
Kind : eBook
Book Rating : 907/5 ( reviews)

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Book Synopsis Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies by : OECD

Download or read book Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies written by OECD. This book was released on 2019-10-17. Available in PDF, EPUB and Kindle. Book excerpt: This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.

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