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Identification of Multiple Targets in the Fight against Alzheimer’s Disease

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Release : 2020-07-31
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Kind : eBook
Book Rating : 096/5 ( reviews)

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Book Synopsis Identification of Multiple Targets in the Fight against Alzheimer’s Disease by : Patrizia Giannoni

Download or read book Identification of Multiple Targets in the Fight against Alzheimer’s Disease written by Patrizia Giannoni. This book was released on 2020-07-31. Available in PDF, EPUB and Kindle. Book excerpt:

Identification of Multiple Targets in the Fight Against Alzheimer's Disease

Download Identification of Multiple Targets in the Fight Against Alzheimer's Disease PDF Online Free

Author :
Release : 2020
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Identification of Multiple Targets in the Fight Against Alzheimer's Disease by : Patrizia Giannoni

Download or read book Identification of Multiple Targets in the Fight Against Alzheimer's Disease written by Patrizia Giannoni. This book was released on 2020. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Improving and Accelerating Therapeutic Development for Nervous System Disorders

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Release : 2014-02-06
Genre : Medical
Kind : eBook
Book Rating : 492/5 ( reviews)

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Book Synopsis Improving and Accelerating Therapeutic Development for Nervous System Disorders by : Institute of Medicine

Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine. This book was released on 2014-02-06. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.

Preventing Alzheimer's Disease

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Release : 2017-02-16
Genre :
Kind : eBook
Book Rating : 073/5 ( reviews)

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Book Synopsis Preventing Alzheimer's Disease by : National Institutes National Institutes oF Health

Download or read book Preventing Alzheimer's Disease written by National Institutes National Institutes oF Health. This book was released on 2017-02-16. Available in PDF, EPUB and Kindle. Book excerpt: This booklet summarizes what scientists have learned so far and where research is headed. There is no definitive evidence yet about what can prevent Alzheimer's or age-related cognitive decline. What we do know is that a healthy lifestyle-one that includes a healthy diet, physical activity, appropriate weight, and no smoking-can maintain and improve overall health and well-being. Making healthy choices can also lower the risk of certain chronic diseases, like heart disease and diabetes, and scientists are very interested in the possibility that a healthy lifestyle might have a beneficial effect on Alzheimer's as well. In the meantime, as research continues to pinpoint what works to prevent Alzheimer's, people of all ages can benefit from taking positive steps to get and stay healthy.

Alzheimer's Disease Drug Development

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Release : 2022-03-31
Genre : Business & Economics
Kind : eBook
Book Rating : 669/5 ( reviews)

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Book Synopsis Alzheimer's Disease Drug Development by : Jeffrey Cummings

Download or read book Alzheimer's Disease Drug Development written by Jeffrey Cummings. This book was released on 2022-03-31. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.

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