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Hypercalcemia of Malignancy

2012-12-06 Medical
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Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 731/5 ( reviews)

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Book Synopsis Hypercalcemia of Malignancy by : Friedhelm Raue

Download or read book Hypercalcemia of Malignancy written by Friedhelm Raue. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Hypercalcemia is the most common life-threatening metabolic disorder associated with cancer. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. With a better understanding of the pathophysiology of this condition and the development of new potent drugs, capable of inhibiting bone resorption, especially bisphosphonates, the clinician will be more successful in correcting hypercalcemia in the great majority of patients.

Practical Clinical Endocrinology

2021-02-24 Medical
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Release : 2021-02-24
Genre : Medical
Kind : eBook
Book Rating : 115/5 ( reviews)

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Book Synopsis Practical Clinical Endocrinology by : Peter Igaz

Download or read book Practical Clinical Endocrinology written by Peter Igaz. This book was released on 2021-02-24. Available in PDF, EPUB and Kindle. Book excerpt: This practical book aims to cover the whole scope of clinical endocrinology, including both common and selected rare but important diseases, with an emphasis on practical clinical management. A number of different questions and problems in clinical routine are discussed in this book in an unconventional format. Each topic begins with the presentation of a typical clinical case, and then the topic is approached in a question and answer format linked to the clinical case presented, highlighting the most important questions in diagnosis, differential diagnosis and therapy. Numerous figures and tables are included to help understanding. The book is chiefly intended for doctors in training (preparing for boarding exam in endocrinology or internal medicine), but also for established clinicians who want to broaden or refresh their skills. University students of medicine can also find this book interesting.

Holland-Frei Cancer Medicine

2017-03-10 Medical
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Release : 2017-03-10
Genre : Medical
Kind : eBook
Book Rating : 84X/5 ( reviews)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr.. This book was released on 2017-03-10. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Parathyroid Hormone - Related Protein

1992-03-04 Medical
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Release : 1992-03-04
Genre : Medical
Kind : eBook
Book Rating : 395/5 ( reviews)

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Book Synopsis Parathyroid Hormone - Related Protein by : Bernard P. Halloran

Download or read book Parathyroid Hormone - Related Protein written by Bernard P. Halloran. This book was released on 1992-03-04. Available in PDF, EPUB and Kindle. Book excerpt: Since its discovery, a substantial body of information has been amassed concerning the functions of parathyroid hormone-related protein (PTHrP) in normal and malignant states. This book provides a state-of-the-art discussion of the major aspects of PTHrP biology and pathophysiology, in addition to presenting a historical perspective and discussions on the molecular biology of PTHrP, its mechanism of action, bioassays and radioimmunoassays, and its role in normal physiology. The book will be a primary resource for physicians interested in the clinical aspects of paraneoplastic hypercalcemia and mineral metabolic disorders. It will also serve as a primary resource for basic scientists in skeletal and renal physiology, tumor biology, and hormone action. PROPOSED CONTENTS: INTRODUCTION (A. BROADUS). HISTORY. Identification of Clinical Syndrome of MAH. Evidence for Unique PTH-Like Factor. ISOLATION AND PURIFICATION OF PTHrP. CHEMICAL DESCRIPTION OF PTHrP. MOLECULAR BIOLOGY OF PTHrP (D. GOLTZMAN). GENE STRUCTURE. Intron and Exon Boundaries. Identification of Promoter and Putative Regulatory Elements. Alternative Splicing. EVOLUTIONARY RELATIONSHIP TO PTH GENE. EXPRESSION OF PTHrP (M. THIEDE). EXPRESSION IN TUMOR TISSUES. EXPRESSION IN NORMAL TISSUES. EXPRESSION IN CELL CULTURE. SECRETED FORMS. ASSAY OF PTHrP AND ITS ROLE IN MAH (A. STEWART, W. BURTIS). BIO- AND RADIOIMMUNOASSAYS. SERUM CONCENTRATIONS IN NORMAL SUBJECTS AND CANCER PATIENTS. RELATIONSHIP BETWEEN EXPRESSION OF PTHRP AND HYPERCALCEMIA. EFFECTS ON TARGET TISSUES. Bone. Kidney. ROLE OF FACTORS OTHER THAN PTHrP IN MAH. MOLECULAR MECHANISM OF ACTION OF PTHrP (R. NISSENSON, G. STREWLER). RECEPTOR BINDING AND CELL SIGNALING. IMPLICATIONS FOR STRUCTURE-FUNCTION FOR PTHrP FAMILY. PTHrP IN NORMAL PHYSIOLOGY (J. MARTIN). EMBRYONIC AND NEONATAL DEVELOPMENT. LACTATION. RELATIONSHIP TO PTH.

Textbook of Palliative Care

2025-05-29 Medical
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Release : 2025-05-29
Genre : Medical
Kind : eBook
Book Rating : 907/5 ( reviews)

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Book Synopsis Textbook of Palliative Care by : Roderick Duncan MacLeod

Download or read book Textbook of Palliative Care written by Roderick Duncan MacLeod. This book was released on 2025-05-29. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides the most up-to-date information on all aspects of palliative care including recent developments (including COVID-19), global policies, service provision, symptom management, professional aspects, organization of services, palliative care for specific populations, palliative care emergencies, ethical issues in palliative care, research in palliative care, public health approaches and financial aspects of care. This new Textbook of Palliative Care remains a unique, comprehensive, clinically relevant and state-of-the art book, aimed at advancing palliative care as a science, a clinical practice and as an art. Palliative care has been part of healthcare for over fifty years but we still needs to be explained. Healthcare education and training has been slow to recognize the vital importance of ensuring that all practitioners have a good understanding of what is involved in the care of people with serious or advanced illnesses and theirfamilies. However, the science of palliative care is advancing and this new edition will contribute to a better understanding of this specialty. This new edition offers 20 new chapters out of over 120, written by experts in their given fields provide up-to-date information on a wide range of topics of relevance to those providing care towards the end of life no matter what the disease may be. We present a global perspective on contemporary and classic issues in palliative care with authors from a wide range of disciplines involved in this essential aspect of care. The Textbook includes sections addressing aspects such as symptom management and care provision, organization of care in different settings, care in specific disease groups, palliative care emergencies, ethics, public health approaches and research in palliative care. This new Textbook will be of value to practitioners in all disciplines and professions where the care of people approaching death is important, specialists as well as non-specialists, in any setting where people with serious advanced illnesses are residing. It is also an important resource for researchers, policy-and decision-makers at national or regional levels. Neither the science nor the art of palliative care will stand still so the Editors and contributors from all over the world aim to keep this Textbook updated so that the reader can find new evidence and approaches to care.

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