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Hormones, Genes, and Cancer

2003-03-13 Medical
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Release : 2003-03-13
Genre : Medical
Kind : eBook
Book Rating : 588/5 ( reviews)

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Book Synopsis Hormones, Genes, and Cancer by : Brian E. Henderson

Download or read book Hormones, Genes, and Cancer written by Brian E. Henderson. This book was released on 2003-03-13. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal carcinogenesis is an important and controversial area of current research. In addition to accelerating existing cancers, can hormones play the role of primary carcinogens? How do genetic factors influence hormone-related cancer risk? Hormones, Genes, and Cancer addresses these questions. Over the past few decades, cancer research has focused on external environmental causes(e.g., tobacco smoke, viruses, asbestos). With the advent of new genetic sequencing techniques, we are just now beginning to understand how the body's internal environment(i.e., the hormones and growth factors that determine normal development) influences cancer etiology and prevention. From molecular insights to clinical analyses, this volume provides state-of-the-art information on the complex interactions between hormones and genes and cancer. The epidemiology and molecular endocrinology of prostate, breast, uterine, ovarian and testicular cancer are detailed in this timely treatise.

Hormones, Genes, and Cancer

2023 Cancer
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Release : 2023
Genre : Cancer
Kind : eBook
Book Rating : 128/5 ( reviews)

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Book Synopsis Hormones, Genes, and Cancer by : Brian E. Henderson

Download or read book Hormones, Genes, and Cancer written by Brian E. Henderson. This book was released on 2023. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal carcinogenesis is an important and controversial area of research. In addition to accelerating existing cancers, can hormones play the role of primary carcinogens? And how do genetic factors influence hormone-related cancer risk? This work addresses these questions.

Cancer and the Environment

2002-08-01 Science
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Release : 2002-08-01
Genre : Science
Kind : eBook
Book Rating : 240/5 ( reviews)

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Book Synopsis Cancer and the Environment by : Institute of Medicine

Download or read book Cancer and the Environment written by Institute of Medicine. This book was released on 2002-08-01. Available in PDF, EPUB and Kindle. Book excerpt: The Roundtable on Environmental Health Sciences, Research, and Medicine wanted to address the link between environmental factors and the development of cancer in light of recent advances in genomics. They asked what research tools are needed, how new scientific information can be applied in a timely manner to reduce the burden of cancer, and how this can be flexible enough to treat the individual.

Hormones and Cancer

2012-12-06 Science
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Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 665/5 ( reviews)

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Book Synopsis Hormones and Cancer by : Wayne V. Vedeckis

Download or read book Hormones and Cancer written by Wayne V. Vedeckis. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: The series, Hormones in Health and Disease, was launched in 1993 to provide a scientific platform for investigators engaged in research on the biological actions of hormones and to anticipate relevance for their findings in clinical applications. The first volume of the series was dedicated to the discussion and understanding of molecular mechanisms by which steroid hormones influence target cells in normal and pathological conditions. With the diversity of information and the vast amount of literature on steroid hormone physiology, a more thorough treatment of Hormones and Cancer was identified as a timely topic. In this second volume in the series, Dr. Wayne V. Vedeckis has success fully undertaken the monumental task of editing the findings of the leading investigators in hormone and cancer research. Dr. Vedeckis brings to this project two decades of research experience in hormone action; he is actively engaged in elucidating hormone and cancer interrelations. It is a pleasure to welcome him to the series as an editor and congratulate him and all contribu tors in presenting this comprehensive treatise. The 20 chapters include discussions on contemporary topics relating control of cell division and signal transduction to the basic mechanisms of carcinogenesis by cloning patient genes, and recognizing the importance of steroid receptors in treatment protocols of various endocrine abnormalities.

Hormonal Carcinogenesis III

2012-12-06 Medical
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Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 920/5 ( reviews)

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Book Synopsis Hormonal Carcinogenesis III by : Jonathan J. Li

Download or read book Hormonal Carcinogenesis III written by Jonathan J. Li. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer fields of molecular genetics and cytogenetics already have and are expected to continue to playa major role in furthering our understanding of the cellular and molecular events in hormonal carcinogenesis. It has become increasingly clear that the risk of naturally occurring sex hormones in carcinogenic processes, both in human and in animal models, requires only minute quantities of hormones, at both the serum and tissue levels. Moreover, hormone target tissues for neoplastic transformation, perhaps with the exception of the liver, generally have relatively modest ability to metabolize sex hormones, such as the breast and prostate. Table 1 summarizes the serum, and in most cases, the tissue levels of sex hormones, both endogenously and exogenously ingested, which are associated with increased risk for endocrine-associated cancers such as breast, endometrium, and prostate, as well as the hormone levels of four experimental models that have been shown to elicit high tumor incidences. In contrast to the human, in which the hormone levels are cyclic, however, the latter require continuous hormone exposure at these relatively low levels.

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