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Heritable Human Genome Editing

2021-01-16 Medical
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Release : 2021-01-16
Genre : Medical
Kind : eBook
Book Rating : 132/5 ( reviews)

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Book Synopsis Heritable Human Genome Editing by : The Royal Society

Download or read book Heritable Human Genome Editing written by The Royal Society. This book was released on 2021-01-16. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Human Genome Editing

2017-08-13 Medical
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Release : 2017-08-13
Genre : Medical
Kind : eBook
Book Rating : 880/5 ( reviews)

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Book Synopsis Human Genome Editing by : National Academies of Sciences, Engineering, and Medicine

Download or read book Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine. This book was released on 2017-08-13. Available in PDF, EPUB and Kindle. Book excerpt: Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Altered Inheritance

2019-09-17 Science
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Release : 2019-09-17
Genre : Science
Kind : eBook
Book Rating : 711/5 ( reviews)

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Book Synopsis Altered Inheritance by : Françoise Baylis

Download or read book Altered Inheritance written by Françoise Baylis. This book was released on 2019-09-17. Available in PDF, EPUB and Kindle. Book excerpt: With the advent of CRISPR gene-editing technology, designer babies have become a reality. Françoise Baylis insists that scientists alone cannot decide the terms of this new era in human evolution. Members of the public, with diverse interests and perspectives, must have a role in determining our future as a species.

Human Germline Modification and the Right to Science

2020-01-09 Law
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Release : 2020-01-09
Genre : Law
Kind : eBook
Book Rating : 872/5 ( reviews)

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Book Synopsis Human Germline Modification and the Right to Science by : Andrea Boggio

Download or read book Human Germline Modification and the Right to Science written by Andrea Boggio. This book was released on 2020-01-09. Available in PDF, EPUB and Kindle. Book excerpt: A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.

Editing Humanity

2020-10-06 Science
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Release : 2020-10-06
Genre : Science
Kind : eBook
Book Rating : 942/5 ( reviews)

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Book Synopsis Editing Humanity by : Kevin Davies

Download or read book Editing Humanity written by Kevin Davies. This book was released on 2020-10-06. Available in PDF, EPUB and Kindle. Book excerpt: One of the world's leading experts on genetics unravels one of the most important breakthroughs in modern science and medicine. IIf our genes are, to a great extent, our destiny, then what would happen if mankind could engineer and alter the very essence of our DNA coding? Millions might be spared the devastating effects of hereditary disease or the challenges of disability, whether it was the pain of sickle-cell anemia to the ravages of Huntington’s disease. But this power to “play God” also raises major ethical questions and poses threats for potential misuse. For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change. Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale. Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.

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