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Heart Regeneration: Stem Cells And Beyond

2012-03-22 Medical
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Release : 2012-03-22
Genre : Medical
Kind : eBook
Book Rating : 259/5 ( reviews)

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Book Synopsis Heart Regeneration: Stem Cells And Beyond by : Felix B Engel

Download or read book Heart Regeneration: Stem Cells And Beyond written by Felix B Engel. This book was released on 2012-03-22. Available in PDF, EPUB and Kindle. Book excerpt: Injured mammalian hearts do not regenerate but scar. This is a major medical problem, as ischemic heart disease is among the leading causes of morbidity and mortality worldwide. Essential clues for human heart repair are uncovered when zebrafish and newt are found to regenerate cardiac muscle after injury.This book presents the major advances of the last decade in the field of cardiac regeneration. These recent advances include: demonstration that zebrafish, a genetically tractable system, can regenerate heart; the identification of several new stem cell populations in the heart; demonstration that stem cells can be used to improve heart function; and demonstration that induction of cardiomyocyte proliferation is a realistic future option to repair injured hearts. This book also provides detailed reviews of the research on model organisms capable of heart regeneration as well as innovative translational research to achieve regeneration in mammals, that comprises work on blood born stem cells, endogenous cardiac stem cells, paracrine factors, reawakening of cardiomyocyte proliferation, and bioengineering. More importantly, the book, in the concluding chapter, dovetails the studies with a comprehensive overview of clinical trials.

Regeneration: Stem Cells and Beyond

2003-09-16 Science
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Release : 2003-09-16
Genre : Science
Kind : eBook
Book Rating : 381/5 ( reviews)

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Book Synopsis Regeneration: Stem Cells and Beyond by : Ellen Heber-Katz

Download or read book Regeneration: Stem Cells and Beyond written by Ellen Heber-Katz. This book was released on 2003-09-16. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Current Topics in Microbiology and Immunology the authors present a unique range of examples of the regenerative response and the role of stem cells from the amphibian to human. It seems that all roads lead to cells that have the plasticity to become something else, not only in the amphibian but also in the mammal.

Cardiac regeneration and angiogenesis beyond stem cell research

2007
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Release : 2007
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Cardiac regeneration and angiogenesis beyond stem cell research by : Adriana C. Gittenberger-de Groot

Download or read book Cardiac regeneration and angiogenesis beyond stem cell research written by Adriana C. Gittenberger-de Groot. This book was released on 2007. Available in PDF, EPUB and Kindle. Book excerpt:

Biomaterials for Cardiac Regeneration

2014-11-12 Technology & Engineering
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Release : 2014-11-12
Genre : Technology & Engineering
Kind : eBook
Book Rating : 723/5 ( reviews)

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Book Synopsis Biomaterials for Cardiac Regeneration by : Erik J. Suuronen

Download or read book Biomaterials for Cardiac Regeneration written by Erik J. Suuronen. This book was released on 2014-11-12. Available in PDF, EPUB and Kindle. Book excerpt: This book offers readers a comprehensive biomaterials-based approach to achieving clinically successful, functionally integrated vasculogenesis and myogenesis in the heart. Coverage is multidisciplinary, including the role of extracellular matrices in cardiac development, whole-heart tissue engineering, imaging the mechanisms and effects of biomaterial-based cardiac regeneration, and autologous bioengineered heart valves. Bringing current knowledge together into a single volume, this book provides a compendium to students and new researchers in the field and constitutes a platform to allow for future developments and collaborative approaches in biomaterials-based regenerative medicine, even beyond cardiac applications.

Stem Cells and Cardiac Regeneration

2015-12-18 Science
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Release : 2015-12-18
Genre : Science
Kind : eBook
Book Rating : 278/5 ( reviews)

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Book Synopsis Stem Cells and Cardiac Regeneration by : Rosalinda Madonna

Download or read book Stem Cells and Cardiac Regeneration written by Rosalinda Madonna. This book was released on 2015-12-18. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an update of recent advances in the basic and clinical applications of cell-based therapies for myocardial repair and regeneration in ischemic heart disease (IHD) and heart failure (HF). The first sections of the book illuminate basic aspects of stem cells such as definitions, isolation criteria and characterization of embryonic and adult stem cells, as well as pluripotent stem cells and tissue specific progenitor and stem cells. In the following section, the text examines the role of critical regulators of stem cell differentiation in myocardial regeneration, that include circadian rhythyms, microRNAs, epigenetics, microvescicles, and exosomes. The text concludes with a review of the use of stem/progenitor cells in cardiac regeneration and discuss current controversies, unresolved issues, challenges, and future directions. Stem Cells and Cardiac Regeneration is addressed to a wide audience consisting of cardiologists, clinicians, and research scientists, who will learn new concepts in cardiovascular regeneration and repair with special focus on molecular mechanisms and therapeutic potential for cardiovascular regeneration.

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