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Genetics and Evolution of Infectious Diseases

2010-12-17 Medical
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Release : 2010-12-17
Genre : Medical
Kind : eBook
Book Rating : 903/5 ( reviews)

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Book Synopsis Genetics and Evolution of Infectious Diseases by : Michel Tibayrenc

Download or read book Genetics and Evolution of Infectious Diseases written by Michel Tibayrenc. This book was released on 2010-12-17. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field

Genetics and Evolution of Infectious Diseases

2024-07-19 Medical
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Release : 2024-07-19
Genre : Medical
Kind : eBook
Book Rating : 194/5 ( reviews)

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Book Synopsis Genetics and Evolution of Infectious Diseases by : Michel Tibayrenc

Download or read book Genetics and Evolution of Infectious Diseases written by Michel Tibayrenc. This book was released on 2024-07-19. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. Takes an integrated approach to infectious diseases Provides the latest developments in the field of infectious diseases Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases Includes updated and revised contributions from leading authorities, along with six new chapters

Evolution in Health and Disease

1999 Adaptation (Physiology)
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Release : 1999
Genre : Adaptation (Physiology)
Kind : eBook
Book Rating : 107/5 ( reviews)

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Book Synopsis Evolution in Health and Disease by : Stephen C. Stearns

Download or read book Evolution in Health and Disease written by Stephen C. Stearns. This book was released on 1999. Available in PDF, EPUB and Kindle. Book excerpt: For most of our history, humans lived in small hunter-gatherer groups whose diets, living conditions, and environmental pressures were very different from what most humans face today. The result is that the evolutionary adaptations which proved beneficial in our past may prove less so now. This fascinating book explores the implications of human evolutionary history for human health and medicine. The topics include the evolution of antibiotic resistance, the evolution of pathogen virulence, the evolution of aging, the design of vaccines, and population- and genotype-specific reactions to drugs and susceptibility to disease. The book also discusses new insights into mother-offspring conflict during pregnancy, menstruation, menopause, child abuse, homicide, depression, schizophrenia, and many chronic degenerative diseases, such as cancer and osteoporosis. Written by leading experts in evolutionary medicine and addressed to medical students and researchers and evolutionary biologists, the book describes the state of the art and provides clear access to the primary literature. It also provides compelling arguments for why the tools evolutionary biology belong in every doctor's tool-kit.

Evolution of Infectious Disease

1994-01-06 Medical
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Release : 1994-01-06
Genre : Medical
Kind : eBook
Book Rating : 01X/5 ( reviews)

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Book Synopsis Evolution of Infectious Disease by : Paul W. Ewald

Download or read book Evolution of Infectious Disease written by Paul W. Ewald. This book was released on 1994-01-06. Available in PDF, EPUB and Kindle. Book excerpt: Findings from the field of evolutionary biology are yielding dramatic insights for health scientists, especially those involved in the fight against infectious diseases. This book is the first in-depth presentation of these insights. In detailing why the pathogens that cause malaria, smallpox, tuberculosis, and AIDS have their special kinds of deadliness, the book shows how efforts to control virtually all diseases would benefit from a more thorough application of evolutionary principles. When viewed from a Darwinian perspective, a pathogen is not simply a disease-causing agent, it is a self-replicating organism driven by evolutionary pressures to pass on as many copies of itself as possible. In this context, so-called "cultural vectors"--those aspects of human behavior and the human environment that allow spread of disease from immobilized people--become more important than ever. Interventions to control diseases don't simply hinder their spread but can cause pathogens and the diseases they engender to evolve into more benign forms. In fact, the union of health science with evolutionary biology offers an entirely new dimension to policy making, as the possibility of determining the future course of many diseases becomes a reality. By presenting the first detailed explanation of an evolutionary perspective on infectious disease, the author has achieved a genuine milestone in the synthesis of health science, epidemiology, and evolutionary biology. Written in a clear, accessible style, it is intended for a wide readership among professionals in these fields and general readers interested in science and health.

Infectious Disease: A Very Short Introduction

2015-06-25 Medical
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Release : 2015-06-25
Genre : Medical
Kind : eBook
Book Rating : 828/5 ( reviews)

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Book Synopsis Infectious Disease: A Very Short Introduction by : Marta Wayne

Download or read book Infectious Disease: A Very Short Introduction written by Marta Wayne. This book was released on 2015-06-25. Available in PDF, EPUB and Kindle. Book excerpt: As doctors and biologists have learned, to their dismay, infectious disease is a moving target: new diseases emerge every year, old diseases evolve into new forms, and ecological and socioeconomic upheavals change the transmission pathways by which disease spread. By taking an approach focused on the general evolutionary and ecological dynamics of disease, this Very Short Introduction provides a general conceptual framework for thinking about disease. Ecology and evolution provide the keys to answering the 'where', 'why', 'how', and 'what' questions about any particular infectious disease: where did it come from? How is it transmitted from one person to another, and why are some individuals more susceptible than others? What biochemical, ecological, and evolutionary strategies can be used to combat the disease? Is it more effective to block transmission at the population level, or to block infection at the individual level? Through a series of case studies, Benjamin Bolker and Marta L. Wayne introduce the major ideas of infectious disease in a clear and thoughtful way, emphasising the general principles of infection, the management of outbreaks, and the evolutionary and ecological approaches that are now central to much research about infectious disease. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

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