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Author : Ramon Latorre
Release : 2014-09-01
Genre :
Kind : eBook
Book Rating : 966/5 ( reviews)
Book Synopsis From Ion Channels to Cell-To-Cell Conversations by : Ramon Latorre
Download or read book From Ion Channels to Cell-To-Cell Conversations written by Ramon Latorre. This book was released on 2014-09-01. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ramón Latorre
Release : 2013-11-21
Genre : Medical
Kind : eBook
Book Rating : 950/5 ( reviews)
Book Synopsis From Ion Channels to Cell-to-Cell Conversations by : Ramón Latorre
Download or read book From Ion Channels to Cell-to-Cell Conversations written by Ramón Latorre. This book was released on 2013-11-21. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels allow us to see nature in all its magnificence, to hear a Bach suite, to smell the aroma of grandmother's cooking, and, in this regard, they put us in contact with the external world. These ion channels are protein molecules located in the cell membrane. In complex organisms, cells need to communicate in order to know about their metabolic status and to act in a coordinate manner. The latter is also accomplished by a class of ion channels able to pierce the lipid bilayer membranes of two adjacent cells. These intercellular channels are the functional subunits of gap junctions. Accordingly, the book is divided in two parts: the first part is dedicated to ion channels that look to the external world, and the second part is dedicated to gap junctions found at cell interfaces. This book is based on a series of symposia for a meeting on ion channels and gap junctions held in Santiago, Chile, on November 28-30, 1995. The book should be useful to graduate students taking the first steps in this field as well as a reference for the aficionado. The aim of the meeting was mainly to show the impact of various modern techniques, including cell biology, molecular biology, biophysics, and molecular genetics techniques in the study of these ubiquitous intrinsic membrane proteins. Molecular-genetics techniques paved the road to the manipulation of the channel forming molecules.
Author : Francisco Sepulveda
Release : 2006-03-30
Genre : Science
Kind : eBook
Book Rating : 243/5 ( reviews)
Book Synopsis Pumps, Transporters, and Ion Channels by : Francisco Sepulveda
Download or read book Pumps, Transporters, and Ion Channels written by Francisco Sepulveda. This book was released on 2006-03-30. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of articles based on some of the talks given at the Centro de Estudios Cientificos (CECS) in Valdivia during the course of a celebration to th mark the 60 birthdays of Ramon Latorre and Enrico Stefani. Ramon Latorre is one of the most outstanding figures in channel Biophysics today. The first surprise is that he trained as a Biochemist! He soon, however, became a biophysicist through his work with Guayo (Eduardo) Rojas who guided him during his Ph. D thesis in the Laboratorio de Fisiologia Celular in Montemar. His work at N.I.H with Gerald Eherenstein and Harold Lecar constitutes one of the milestones of single ion channel Biophysics. This classical work, done in planar bilayers, set the basis for understanding voltage-dependent conductances with single channel studies and predates, by many years, later studies using patch clamping techniques. Ramon was one of the firsts to find and recognize the importance of calci- activated potassium channels and to begin a detailed study of channel properties. He pioneered the ideas of voltage and calcium modulation of the open probability and he added detailed studies of gating and its modulation by other ions. Ramon is also interested in permeation and selectivity and he produced classical studies on the number of water molecules in the channel and sites occupied by barium. Results and concepts that have recently taken front page as the structure of KcSa has been described.
Author : Nikita Gamper
Release : 2016-05-01
Genre : Science
Kind : eBook
Book Rating : 095/5 ( reviews)
Book Synopsis Ion Channels by : Nikita Gamper
Download or read book Ion Channels written by Nikita Gamper. This book was released on 2016-05-01. Available in PDF, EPUB and Kindle. Book excerpt: This Methods in Molecular Biology book offers strategies and protocols for studying a large group of proteins that form ionic channels in the plasma membrane and intracellular membranes of cells. Includes step-by-step protocols, materials lists, tips and more."
Author : David J. Aidley
Release : 1996-08-13
Genre : Medical
Kind : eBook
Book Rating : 821/5 ( reviews)
Book Synopsis Ion Channels by : David J. Aidley
Download or read book Ion Channels written by David J. Aidley. This book was released on 1996-08-13. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels are crucial components of living cells. Situated in the cell's membranes. they allow particular ions to pass from one side of the membrane to the other. In recent years the patch clamp technique has allowed the activity of individual channels to be measured, and recombinant DNA technology has led to fascinating detail on their structure. Together, these technical advances have produced a great flowering of knowledge and understanding about the subject, itself leading to further breakthroughs in science and medicine. Ion Channels provides an introduction to this scientific endeavour. It emphasises the molecular structure of channels as determined by gene cloning technology. This knowledge illuminates discussions of the permeability and selectivity of channels, their gating and modulation, their responses to drugs and toxins and the human diseases caused when they do not function properly.
