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Folding for the Synapse

2010-10-22 Medical
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Release : 2010-10-22
Genre : Medical
Kind : eBook
Book Rating : 614/5 ( reviews)

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Book Synopsis Folding for the Synapse by : Andreas Wyttenbach

Download or read book Folding for the Synapse written by Andreas Wyttenbach. This book was released on 2010-10-22. Available in PDF, EPUB and Kindle. Book excerpt: Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.

Folding for the Synapse

2010-10-25 Medical
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Release : 2010-10-25
Genre : Medical
Kind : eBook
Book Rating : 602/5 ( reviews)

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Book Synopsis Folding for the Synapse by : Andreas Wyttenbach

Download or read book Folding for the Synapse written by Andreas Wyttenbach. This book was released on 2010-10-25. Available in PDF, EPUB and Kindle. Book excerpt: Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.

Structural and Functional Organization of the Synapse

2008-06-25 Medical
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Release : 2008-06-25
Genre : Medical
Kind : eBook
Book Rating : 324/5 ( reviews)

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Book Synopsis Structural and Functional Organization of the Synapse by : Johannes W. Hell

Download or read book Structural and Functional Organization of the Synapse written by Johannes W. Hell. This book was released on 2008-06-25. Available in PDF, EPUB and Kindle. Book excerpt: This new Springer volume, which comes complete with a free DVD, is a comprehensive and detailed overview of the synapse with emphasis on the glutamatergic synapse. Most chapters relate the synapse’s functional aspects to its molecular mechanisms. This approach shows which mechanisms are characterized on both the functional and structural level and can thus be considered firmly established. It’s an important text for neuroscientists and disease-oriented clinicians in neurology.

The Sticky Synapse

2009-06-07 Medical
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Release : 2009-06-07
Genre : Medical
Kind : eBook
Book Rating : 085/5 ( reviews)

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Book Synopsis The Sticky Synapse by : Michael Hortsch

Download or read book The Sticky Synapse written by Michael Hortsch. This book was released on 2009-06-07. Available in PDF, EPUB and Kindle. Book excerpt: The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions. As synapses present specialized cellular junctions between neurons and their target cells, it may not come as a surprise that neural cell adhesion molecules (CAMs) are of special importance for the genesis and the maintenance of synaptic connections. Genes encoding adhesive molecules make up a significant portion of the human genome, and neural CAMs even have been postulated to be a major factor in the evolution of the human brain. These are just some of the many reasons why we thought a book on neural CAMs and their role in establishing and maintaining neuronal synapses would be highly appropriate for summarizing our current state of knowledge. Without question, over the near future, additional adhesive proteins will join the ranks of synaptic CAMs and our knowledge, and how these molecules enable neurons and their targets to communicate effectively will grow.

The Physiology of Synapses

2013-10-22 Medical
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Release : 2013-10-22
Genre : Medical
Kind : eBook
Book Rating : 069/5 ( reviews)

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Book Synopsis The Physiology of Synapses by : John Carew Eccles

Download or read book The Physiology of Synapses written by John Carew Eccles. This book was released on 2013-10-22. Available in PDF, EPUB and Kindle. Book excerpt: The Physiology of Synapses covers the considerable advances in understanding the complex physiology of synapses. This book is divided into 16 chapters that emphasize the mechanism of synaptic transmission. The first chapters describe the structural and physiological features of chemically transmitting synapses. The subsequent chapters deal with the excitatory postsynaptic responses to presynaptic impulse and the release of transmitter by presynaptic impulses. These topics are followed by discussions of the impulse generation by the excitatory postsynaptic potential; the postsynaptic electrical events produced by chemically transmitting inhibitory synapses; the ionic mechanism generating the inhibitory postsynaptic potential. The last chapters consider the mechanism of inhibitory transmitter substances, pathways responsible for postsynaptic inhibitory action, and the trophic and plastic properties of synapses. This book will prove useful to physiologists, neurologists, and researchers.

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