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Extracellular Matrix in the Kidney

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Author :
Release : 1994
Genre : Medical
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Extracellular Matrix in the Kidney by : Hikaru Koide

Download or read book Extracellular Matrix in the Kidney written by Hikaru Koide. This book was released on 1994. Available in PDF, EPUB and Kindle. Book excerpt:

Extracellular Matrix Biology

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Author :
Release : 2012
Genre : Cell interaction
Kind : eBook
Book Rating : 385/5 ( reviews)

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Book Synopsis Extracellular Matrix Biology by : Richard O. Hynes

Download or read book Extracellular Matrix Biology written by Richard O. Hynes. This book was released on 2012. Available in PDF, EPUB and Kindle. Book excerpt: In most tissues, cells are surrounded by an extracellular matrix (ECM) containing proteins such as collagen, laminin, and fibronectin. The ECM plays an important role in regulating cell function. ECM proteins bind to integrins and other cell surface receptors, activating signaling pathways that regulate cellular morphology, adhesion, cell migration, cell proliferation, and apoptosis. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers all aspects of ECM composition and function, as well as alterations in the ECM that occur during development, tumorigenesis, and other disease states. The contributors examine the various ECM proteins and proteoglycans, ECM receptors such as integrins, and the signaling pathways that mediate the effects of the ECM on cells. They also describe ECM functions in specific biological contexts, including angiogenesis, hemostasis, and thrombosis. Covering not only the biochemistry and cell biology of the ECM but also its roles in development, physiology, and pathology, this volume is an indispensable reference for cell biologists and all those interested in exploring the myriad functions of the ECM.

Renal Fibrosis: Mechanisms and Therapies

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Release : 2019-08-09
Genre : Science
Kind : eBook
Book Rating : 717/5 ( reviews)

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Book Synopsis Renal Fibrosis: Mechanisms and Therapies by : Bi-Cheng Liu

Download or read book Renal Fibrosis: Mechanisms and Therapies written by Bi-Cheng Liu. This book was released on 2019-08-09. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions.

Molecular Biology of the Cell

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Author :
Release : 2002
Genre : Cells
Kind : eBook
Book Rating : 183/5 ( reviews)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by . This book was released on 2002. Available in PDF, EPUB and Kindle. Book excerpt:

Extracellular Matrix Abnormalities in Polycystic Kidney Disease

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Author :
Release : 2012
Genre : Medicine
Kind : eBook
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Book Synopsis Extracellular Matrix Abnormalities in Polycystic Kidney Disease by : Soundarapandian Vijayakumar

Download or read book Extracellular Matrix Abnormalities in Polycystic Kidney Disease written by Soundarapandian Vijayakumar. This book was released on 2012. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular Matrix Abnormalities in Polycystic Kidney Disease.

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