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Extracellular Matrix for Tissue Engineering and Biomaterials

2018-04-13 Science
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Release : 2018-04-13
Genre : Science
Kind : eBook
Book Rating : 233/5 ( reviews)

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Book Synopsis Extracellular Matrix for Tissue Engineering and Biomaterials by : Anna C. Berardi

Download or read book Extracellular Matrix for Tissue Engineering and Biomaterials written by Anna C. Berardi. This book was released on 2018-04-13. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a state-of-art-report on the new methodologies in tissue engineering and developments in the biomaterials field based on the extracellular matrix-relevant discovery. Extracellular Matrix for Tissue Engineering and Biomaterials opens with an overview of the latest extracellular matrix research and in Part I, focuses on its biology and its role on cell behavior and cell fate relevant for the design of biomimetic surfaces. Part II details issues regarding the strategies currently applied in the research of biologically inspired materials and material systems for the replacement, repair and regeneration of tissues and organs. Part III presents the latest development methods applying knowledge from biology towards nanotechnology, to promote the restoration of the functionality of a living tissue. The book ranges from fundamental biology associated with tissue regeneration for the development of biomimetic approaches to controlling tissue formation, cell function, differentiation and angiogenesis using factors involved in normal tissue development and function. With the breadth and depth of the coverage of this topic, this book will serve as a valuable reference for anyone working in tissue engineering or biomaterials – from scientists, chemists and biologists through physicists, bioengineers and clinicians.

Decellularized Extracellular Matrix

2019-12-05 Technology & Engineering
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Release : 2019-12-05
Genre : Technology & Engineering
Kind : eBook
Book Rating : 264/5 ( reviews)

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Book Synopsis Decellularized Extracellular Matrix by : Tetsuji Yamaoka

Download or read book Decellularized Extracellular Matrix written by Tetsuji Yamaoka. This book was released on 2019-12-05. Available in PDF, EPUB and Kindle. Book excerpt: The extracellular matrix (ECM) supports cells and regulates various cellular functions in our body. The native ECM promises to provide an excellent scaffold for regenerative medicine. In order to use the ECM as a scaffold in medicine, its cellular fractions need to be removed while retaining its structural and compositional properties. This process is called decellularization, and the resulting product is known as the decellularized extracellular matrix (dECM). This book focuses on the sources of dECM and its preparation, characterization techniques, fabrication, and applications in regenerative medicine and biological studies. Using this book, the reader will gain a good foundation in the field of ECM decellularization complemented with a broad overview of dECM characterization, ranging from structural observation and compositional assessment to immune responses against dECM and applications, ranging from microfabrication and 3D-printing to the application of tissue-derived dECM in vascular grafts and corneal tissue engineering etc. The book closes with a section dedicated to cultured cell dECM, a complementary technique of tissue-derived dECM preparation, for application in tissue engineering and regenerative medicine, addressing its use in stem cell differentiation and how it can help in the study of the tumor microenvironment as well as in clinical trials of peripheral nerve regeneration.

Extracellular Matrix-derived Implants in Clinical Medicine

2016-05-18 Technology & Engineering
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Release : 2016-05-18
Genre : Technology & Engineering
Kind : eBook
Book Rating : 19X/5 ( reviews)

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Book Synopsis Extracellular Matrix-derived Implants in Clinical Medicine by : Daniel L Mooradian

Download or read book Extracellular Matrix-derived Implants in Clinical Medicine written by Daniel L Mooradian. This book was released on 2016-05-18. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular Matrix-Derived Implants in Clinical Medicine comprehensively covers the emergence of tissue engineering and regenerative medicine over the past few decades, along with discussions of continuous funding and research. The book provides a state-of-the-art review of this increasingly important technology and how it is translating from bench to bedside. Part One of the book looks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurological, while Part Two examines the challenges in harvesting, processing, and manufacturing of extracellular matrices, with a final section reviewing the international regulatory environment and economics of tissue-based products. Addresses issues of tissue engineering and regenerative medicine from a biomaterials industry perspective Looks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurological Examines the challenges in harvesting, processing, and manufacturing of extracellular matrices Reviews the international regulatory environment and economics of tissue-based products

Mimicking the Extracellular Matrix

2019-03-15 Technology & Engineering
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Release : 2019-03-15
Genre : Technology & Engineering
Kind : eBook
Book Rating : 15X/5 ( reviews)

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Book Synopsis Mimicking the Extracellular Matrix by : Gregory A Hudalla

Download or read book Mimicking the Extracellular Matrix written by Gregory A Hudalla. This book was released on 2019-03-15. Available in PDF, EPUB and Kindle. Book excerpt: The extracellular matrix (ECM) is the focus of much interest in biology and bioengineering. Increasing understanding of the influence of the ECM on cell behaviour has led to the exciting possibilities of tissue engineering. Aside from new therapeutic tools, understanding the ECM is of course fundamental to basic cell biology research. Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Seven topics are approached each in a pair of chapters, one with a biological approach and its partner with a bioengineering approach. Topics include the mechanical properties of the ECM, which outlines current knowledge of the ECM physical structure and reviewing state-of-the-art strategies to mimic its native microenvironments. The organisational characteristics of the ECM form the focus of another pair of chapters, where the collagen triple helix is discussed, followed by a review of advances in artificial reproduction of well-ordered systems using self-assembling peptides, or peptide amphiphiles. The balanced approach of this text gives it a broad appeal to those interested in the ECM from a range of backgrounds and disciplines. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials.

Cell-Derived Matrices Part B

2020-04-23 Science
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Release : 2020-04-23
Genre : Science
Kind : eBook
Book Rating : 754/5 ( reviews)

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Book Synopsis Cell-Derived Matrices Part B by :

Download or read book Cell-Derived Matrices Part B written by . This book was released on 2020-04-23. Available in PDF, EPUB and Kindle. Book excerpt: Cell-Derived Matrices Part B, Volume 157 provides a detailed description and step-by-step methods surrounding the use of three-dimensional cell-derived matrices for tissue engineering applications. Chapters in this new release include Glaucomatous cell-derived matrices, Cardiac tissue explants decellularization, Decellularization of skin matrices for wound healing applications, Guiding axonal growth by aligned cell-derived matrices for spinal cord injury regeneration, Human Mesenchymal Stem Cell–Derived Matrices for Enhanced Osteoregeneration, Amniotic decellularized matrices, Three-Dimensional (3-D) Tissue Reconstruction without Scaffold, Tubular cell-derived matrices for TERM applications, and more. Contains contributions from leading experts in the field from across the globe Covers a wide array of topics surrounding the use of cell-derived matrices for tissue engineering and regenerative medicine applications Includes relevant, analysis-based topics, such as the quantification of mechanical properties, decellularization protocols, and innovative matrix engineering methods

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