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Extracellular Matrix Biomineralization of Dental Tissue Structures

2021-09-30 Medical
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Release : 2021-09-30
Genre : Medical
Kind : eBook
Book Rating : 831/5 ( reviews)

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Book Synopsis Extracellular Matrix Biomineralization of Dental Tissue Structures by : Michel Goldberg

Download or read book Extracellular Matrix Biomineralization of Dental Tissue Structures written by Michel Goldberg. This book was released on 2021-09-30. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the structural and biological properties of dental and peridental tissue structures and covers their mineralization process. The book contains a description of dentines, cementum, enamel and bone, including collagens, as well as non-collagenous proteins (SIBLINGs, SLRPs, GAGs, PGs, lipids, and MMPs). The mechanisms of mineralization are described in detail and the book is focused on matrix vesicles, collagen mineralization and the role of non-collagenous extracellular matrix components either as promoters or inhibitors of mineralization. In addition, the matrix components (non-collagenous) of enamel (amelogenin, ameloblastin, enamelin, MMP4, MMP20 and other proteases) are reviewed and their respective roles in dental tissues biomineralizations and tissue turnover are discussed. Additionally, environmental factors involved in enamel / dentin defects are adressed. With state-of-the-art contributions from experts in the respective domains, the book is a useful introduction to the field for junior scientists, interested in dental and peridental tissue biomineralization. It is also an interesting read for advanced scientists and clinicians working in dental research, giving them a broader view of the topic beyond their area of specialization. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Phosphorylated Extracellular Matrix Proteins of Bone and Dentin

2012-09-11 Medical
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Release : 2012-09-11
Genre : Medical
Kind : eBook
Book Rating : 659/5 ( reviews)

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Book Synopsis Phosphorylated Extracellular Matrix Proteins of Bone and Dentin by : Michel Goldberg

Download or read book Phosphorylated Extracellular Matrix Proteins of Bone and Dentin written by Michel Goldberg. This book was released on 2012-09-11. Available in PDF, EPUB and Kindle. Book excerpt: Phosphorylated Extracellular Matrix Proteins of Bone and Dentin is the second volume of the e-book series Frontiers between Science and Clinic in Odontology. The phosphorylated proteins of the extracellular matrix of bone and teeth play a crucial structural role in the two tissues. They also act as signaling molecules. Phosphorylated extracellular matrix proteins have been implicated in nucleation and mineralization of skeletal tissues. This e-book covers research on these specific proteins, including details about the cells producing these molecules, their impact on bone and teeth pathology (osteogenesis and dentinogenesis imperfecta) and the potential of these molecules in promoting of inhibiting mineralization. This e-book also explains processes under the control of some enzymes - TNAP and metalloproteases (MMPs) - such as intracellular regulation in bone and dentine, splicing, respective roles of cleavage products, SIBLINGs, nucleation and crystal growth and regulation. This second volume serves as a valuable reference to practicing odontologists, biology and biomaterials scientists and tissue engineers interested in protein research related to tooth and bone formation.

Engineering Mineralized and Load Bearing Tissues

2015-11-07 Science
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Release : 2015-11-07
Genre : Science
Kind : eBook
Book Rating : 453/5 ( reviews)

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Book Synopsis Engineering Mineralized and Load Bearing Tissues by : Luiz E. Bertassoni

Download or read book Engineering Mineralized and Load Bearing Tissues written by Luiz E. Bertassoni. This book was released on 2015-11-07. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive overview of current challenges and strategies to regenerate load-bearing and calcified human tissues, including bone, cartilage,tendon, ligaments and dental structures (dentin, enamel, cementum and periodontal ligament). Tissue engineering has long held great promises as an improved treatment option for conditions affecting mineralized and load-bearing structures in the body. Although significant progress has been achieved in recent years, a number of challenges still exist. Scaffold vascularization, new biofabrication methods (3D printing, lithography, microfabrication), peptide conjugation methods, interface engineering, scaffold mechanical properties, iPS cells, organs-on-a-chip, are some of the topics discussed in this book. More specially, in the first section readers will find an overview of emerging biofabrication methods. In section 2, applied strategies for regeneration of (2.1) bone, cartilage and ligament, as well as (2.2) dentin, cementum, enamel and periodontal ligament are discussed across 14 chapters. While other volumes have addressed the regeneration of individual tissues, or exclusively focused on different regenerative strategies, the focus of this work is to bring together researchers integrating backgrounds in materials sciences, engineering, biology, mechanics, fluidics, etc, to address specific challenges common to regeneration of several load-bearing and calcified tissues. Therefore, this book provides a unique platform to stimulate progress in the regeneration of functional tissue substitutes. We envision that this book will represent a valuable reference source for university and college faculties, post‐doctoral research fellows, senior graduate students, and researchers from R&D laboratories in their endeavors to fabricate biomimetic load bearing tissues.

Odontogenesis

1995 Dentition
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Release : 1995
Genre : Dentition
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Odontogenesis by : J. V. Ruch

Download or read book Odontogenesis written by J. V. Ruch. This book was released on 1995. Available in PDF, EPUB and Kindle. Book excerpt:

Dental Enamel

2008-04-30 Medical
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Release : 2008-04-30
Genre : Medical
Kind : eBook
Book Rating : 325/5 ( reviews)

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Book Synopsis Dental Enamel by : Derek J. Chadwick

Download or read book Dental Enamel written by Derek J. Chadwick. This book was released on 2008-04-30. Available in PDF, EPUB and Kindle. Book excerpt: The molecular mechanisms and protein species associated with the mineralization of mature dental enamel are active areas of research. This book focuses on specific areas of research including the structural chemistry, protein biochemistry and genetics of enamel development.

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