Evolutionary Genomics and Systems Biology

2011-09-26 Science

Author : Gustavo Caetano-Anoll¿s
Release : 2011-09-26
Genre : Science
Kind : eBook
Book Rating : 719/5 ( reviews)

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Book Synopsis Evolutionary Genomics and Systems Biology by : Gustavo Caetano-Anoll¿s

Download or read book Evolutionary Genomics and Systems Biology written by Gustavo Caetano-Anoll¿s. This book was released on 2011-09-26. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.

Introduction to Evolutionary Genomics

2014-01-22 Computers

Author : Naruya Saitou
Release : 2014-01-22
Genre : Computers
Kind : eBook
Book Rating : 049/5 ( reviews)

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Book Synopsis Introduction to Evolutionary Genomics by : Naruya Saitou

Download or read book Introduction to Evolutionary Genomics written by Naruya Saitou. This book was released on 2014-01-22. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.

Evolutionary Systems Biology

2021-08-05 Science

Author : Anton Crombach
Release : 2021-08-05
Genre : Science
Kind : eBook
Book Rating : 372/5 ( reviews)

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Book Synopsis Evolutionary Systems Biology by : Anton Crombach

Download or read book Evolutionary Systems Biology written by Anton Crombach. This book was released on 2021-08-05. Available in PDF, EPUB and Kindle. Book excerpt: This new edition captures the advances made in the field of evolutionary systems biology since the publication of the first edition. The first edition focused on laying the foundations of evolutionary systems biology as an interdisciplinary field, where a way of thinking and asking questions is combined with a wide variety of tools, both experimental and theoretical/computational. Since publication of the first edition, evolutionary systems biology is now a well-known term describing this growing field. The new edition provides an overview of the current status and future developments of this interdisciplinary field. Chapters highlight several key achievements from the last decade and outline exciting new developments, including an understanding of the interplay between complexity and predictability in evolutionary systems, new viewpoints and methods to study organisms in evolving populations at the level of the genome, gene regulatory network, and metabolic network, and better analysis and modeling techniques that will open new avenues of scientific inquiry.

The Logic of Chance

2011-06-23 Science

Author : Eugene V. Koonin
Release : 2011-06-23
Genre : Science
Kind : eBook
Book Rating : 17X/5 ( reviews)

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Book Synopsis The Logic of Chance by : Eugene V. Koonin

Download or read book The Logic of Chance written by Eugene V. Koonin. This book was released on 2011-06-23. Available in PDF, EPUB and Kindle. Book excerpt: The Logic of Chance offers a reappraisal and a new synthesis of theories, concepts, and hypotheses on the key aspects of the evolution of life on earth in light of comparative genomics and systems biology. The author presents many specific examples from systems and comparative genomic analysis to begin to build a new, much more detailed, complex, and realistic picture of evolution. The book examines a broad range of topics in evolutionary biology including the inadequacy of natural selection and adaptation as the only or even the main mode of evolution; the key role of horizontal gene transfer in evolution and the consequent overhaul of the Tree of Life concept; the central, underappreciated evolutionary importance of viruses; the origin of eukaryotes as a result of endosymbiosis; the concomitant origin of cells and viruses on the primordial earth; universal dependences between genomic and molecular-phenomic variables; and the evolving landscape of constraints that shape the evolution of genomes and molecular phenomes. "Koonin's account of viral and pre-eukaryotic evolution is undoubtedly up-to-date. His "mega views" of evolution (given what was said above) and his cosmological musings, on the other hand, are interesting reading." Summing Up: Recommended Reprinted with permission from CHOICE, copyright by the American Library Association.

Evolutionary Systems Biology

2012-07-23 Science

Author : Orkun S. Soyer
Release : 2012-07-23
Genre : Science
Kind : eBook
Book Rating : 676/5 ( reviews)

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Book Synopsis Evolutionary Systems Biology by : Orkun S. Soyer

Download or read book Evolutionary Systems Biology written by Orkun S. Soyer. This book was released on 2012-07-23. Available in PDF, EPUB and Kindle. Book excerpt: The book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework. An evolutionary approach might allow understanding the significance of observed diversity, uncover “evolutionary design principles” and extend predictions made in model organisms to others. In addition, evolutionary systems biology can generate new insights into the adaptive landscape by combining molecular systems biology models and evolutionary simulations. This insight can enable the development of more detailed mechanistic evolutionary hypotheses.

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