1# Library to Find Best eBook for Read
Author : Amir Kalali
Release : 2012-06-07
Genre : Medical
Kind : eBook
Book Rating : 060/5 ( reviews)
Book Synopsis Essential CNS Drug Development by : Amir Kalali
Download or read book Essential CNS Drug Development written by Amir Kalali. This book was released on 2012-06-07. Available in PDF, EPUB and Kindle. Book excerpt: Presents the complicated process of CNS drug development in a way that is engaging and informative for professionals and students.
Author : Amir Kalali
Release : 2014-05-14
Genre : Central nervous system stimulants
Kind : eBook
Book Rating : 760/5 ( reviews)
Book Synopsis Essential CNS Drug Development. Edited by Amir Kalali ... [Et Al.] by : Amir Kalali
Download or read book Essential CNS Drug Development. Edited by Amir Kalali ... [Et Al.] written by Amir Kalali. This book was released on 2014-05-14. Available in PDF, EPUB and Kindle. Book excerpt: Presents the complicated process of CNS drug development in a way that is engaging and informative for professionals and students.
Author : John Kelly
Release : 2009-10-27
Genre : Medical
Kind : eBook
Book Rating : 913/5 ( reviews)
Book Synopsis Principles of CNS Drug Development by : John Kelly
Download or read book Principles of CNS Drug Development written by John Kelly. This book was released on 2009-10-27. Available in PDF, EPUB and Kindle. Book excerpt: This title acts as a primer, giving students and newcomers to the field an opportunity to learn about the breadth of the CNS drug discovery. The book outlines the core processes in drug discovery and development for CNS disorders, from evaluating drugs for desirable efficacy, safety and pharmacokinetic features in preclinical (using in vitro and in vivo models) and clinical experimentation to identifying future drug targets. Containing up-to-date experimental evidence and detailing the main impediments in the pipeline of CNS drug discovery and development, this is a key reference for those involved in all stages of CNS drug discovery. Key Features: Discusses in detail the key stages of CNS drug discovery, outlining the particular requirements and obstacles for CNS drugs Addresses safety concerns and future drug targets Provides succinct background information about the major CNS diseases Examples of specific drugs are used throughout to describe the development of a new drug from conception to clinical use and post-market surveillance Primary reasons for drug failure are given for each stage
Author : Rudy Schreiber
Release : 2022-06-18
Genre : Medical
Kind : eBook
Book Rating : 531/5 ( reviews)
Book Synopsis Modern CNS Drug Discovery by : Rudy Schreiber
Download or read book Modern CNS Drug Discovery written by Rudy Schreiber. This book was released on 2022-06-18. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug. Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.
Author : Neal R. Cutler
Release : 2010-01-22
Genre : Medical
Kind : eBook
Book Rating : 586/5 ( reviews)
Book Synopsis Critical Pathways to Success in CNS Drug Development by : Neal R. Cutler
Download or read book Critical Pathways to Success in CNS Drug Development written by Neal R. Cutler. This book was released on 2010-01-22. Available in PDF, EPUB and Kindle. Book excerpt: Covering the latest advances in CNS drug development, this bookwill guide all those involved in pre-clinical to early clinicaltrials. The authors describe how recent innovations can acceleratethe development of novel CNS compounds, improve early detection ofefficacy and toxicity signals, and increase the safety oflater-stage clinical trials. The current crisis in the drug development industry iscritically reviewed, as well as the steps needed to correct theproblems, including new government-backed regulations andindustry-based innovations designed to accelerate CNS drugdevelopment in the future. Animal-based models of major CNS disorders are described indetail, and the ability of the latest in vitro and computer-basedmodels to simulate CNS disease states and predict drug efficacy andside-effects are examined. Particular attention is given tothe growing use of biomarkers and how they can be used effectivelyin early human trials as signals of potential drug efficacy, aswell as the increasingly important role of imaging studies to guidedose selection. Cognitive assessments that can be useful indicatorsof effect in patient populations are also discussed. Written by a team of clinical scientists involved in CNS drugtrials for over 20 years, and based on a wealth of drug developmentand clinical trial experience, Critical Pathways to Success inCNS Drug Developmentis full of practical advice forsuccessfully designing and executing CNS drug trials, avoidingpotential pitfalls, and complying with government regulations
