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DNA-Protein Interactions

1993-04-30 Medical
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Release : 1993-04-30
Genre : Medical
Kind : eBook
Book Rating : 906/5 ( reviews)

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Book Synopsis DNA-Protein Interactions by : A. Travers

Download or read book DNA-Protein Interactions written by A. Travers. This book was released on 1993-04-30. Available in PDF, EPUB and Kindle. Book excerpt: The binding of proteins to DNA and the manipulation of DNA by proteins are crucial aspects of the biological role of DNA in the living cell. This book provides a comprehensive and lucid discussion of the molecular interactions involved.

DNA'Protein Interactions

2008-02-02 Science
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Release : 2008-02-02
Genre : Science
Kind : eBook
Book Rating : 082/5 ( reviews)

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Book Synopsis DNA'Protein Interactions by : Tom Moss

Download or read book DNA'Protein Interactions written by Tom Moss. This book was released on 2008-02-02. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Tom Moss assembles the new standard collection of cutting-edge techniques to identify key protein-DNA interactions and define their components, their manner of interaction, and their manner of function, both in the cell and in the test tube. The techniques span a wide range, from factor identification to atomic detail, and include multiple DNA footprinting analyses, including in vivo strategies, gel shift (EMSA) optimization, SELEX, surface plasmon resonance, site-specific DNA-protein crosslinking, and UV laser crosslinking. Comprehensive and broad ranging, DNA-Protein Interactions: Principles and Protocols, 2nd Edition, offers a stellar array of over 100 up-to-date and readily reproducible techniques that biochemists and molecular, cellular, and developmental biologists can use successfully today to understand DNA-protein interactions.

Biophysics of DNA-Protein Interactions

2012-12-05 Science
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Release : 2012-12-05
Genre : Science
Kind : eBook
Book Rating : 950/5 ( reviews)

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Book Synopsis Biophysics of DNA-Protein Interactions by : Mark C. Williams

Download or read book Biophysics of DNA-Protein Interactions written by Mark C. Williams. This book was released on 2012-12-05. Available in PDF, EPUB and Kindle. Book excerpt: Depite the rapid expansion of the field of biophysics, there are very few books that comprehensively treat specific topics in this area. Recently, the field of single molecule biophysics has developed very quickly, and a few books specifically treating single molecule methods are beginning to appear. However, the promise of single molecule biophysics is to contribute to the understanding of specific fields of biology using new methods. This book would focus on the specific topic of the biophysics of DNA-protein interactions, and would include the use of new approaches, including both bulk methods as well as single molecule methods. This would make the book attractive to anyone working in the general area of DNA-protein interactions, which is of course a much wider market than just single molecule biophysicists or even biophysicists. The subject of the book will be the biophysics of DNA-protein interactions, and will include new methods and results that describe the physical mechanism by which proteins interact with DNA. For example, there has been much recent work on the mechanism by which proteins search for specific binding sites on DNA. A few chapters will be devoted to experiments and theory that shed light on this important problem. We will also cover proteins that alter DNA properties to facilitate interactions important for transcription or replication. Another section of the book will cover the biophysical mechanism by which motor proteins interact with DNA. Finally, we will cover larger protein-DNA complexes, such as replication forks, recombination complexes, DNA repair interactions, and their chromatin context.

Introduction to Protein-DNA Interactions

2013 Science
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Release : 2013
Genre : Science
Kind : eBook
Book Rating : 491/5 ( reviews)

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Book Synopsis Introduction to Protein-DNA Interactions by : Gary Stormo

Download or read book Introduction to Protein-DNA Interactions written by Gary Stormo. This book was released on 2013. Available in PDF, EPUB and Kindle. Book excerpt: One of the foundations of molecular biology is how the interactions of proteins with DNA control many aspects of gene expression. Since the mid-20th century discoveries of the lac repressor and operator and the competition between the cI and cro proteins for the same segment of DNA, we have learned an enormous amount about the interactions of proteins with DNA and their control of fundamental processes in the cell. Introduction to Protein-DNA Interactions: Structure, Thermodynamics, and Bioinformatics describes what we know about protein-DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics and how each perspective informs the others. A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create unified view of the field and a fuller understanding of protein-DNA interactions.

Protein-Nucleic Acid Interactions

2008-05-22 Science
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Release : 2008-05-22
Genre : Science
Kind : eBook
Book Rating : 725/5 ( reviews)

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Book Synopsis Protein-Nucleic Acid Interactions by : Phoebe A. Rice

Download or read book Protein-Nucleic Acid Interactions written by Phoebe A. Rice. This book was released on 2008-05-22. Available in PDF, EPUB and Kindle. Book excerpt: This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.

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