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Author : Denis Noble
Release : 2017
Genre : Medical
Kind : eBook
Book Rating : 247/5 ( reviews)
Book Synopsis Dance to the Tune of Life by : Denis Noble
Download or read book Dance to the Tune of Life written by Denis Noble. This book was released on 2017. Available in PDF, EPUB and Kindle. Book excerpt: This book formulates a relativistic theory of biology, challenging the common gene-centred view of organisms.
Author : Denis Noble
Release : 2008-02-14
Genre : Science
Kind : eBook
Book Rating : 800/5 ( reviews)
Book Synopsis The Music of Life by : Denis Noble
Download or read book The Music of Life written by Denis Noble. This book was released on 2008-02-14. Available in PDF, EPUB and Kindle. Book excerpt: What is Life? Decades of research have resulted in the full mapping of the human genome - three billion pairs of code whose functions are only now being understood. The gene's eye view of life, advocated by evolutionary biology, sees living bodies as mere vehicles for the replication of the genetic codes. But for a physiologist, working with the living organism, the view is a very different one. Denis Noble is a world renowned physiologist, and sets out an alternative view to the question - one that becomes deeply significant in terms of the living, breathing organism. The genome is not life itself. Noble argues that far from genes building organisms, they should be seen as prisoners of the organism. The view of life presented in this little, modern, post-genome project reflection on the nature of life, is that of the systems biologist: to understand what life is, we must view it at a variety of different levels, all interacting with each other in a complex web. It is that emergent web, full of feedback between levels, from the gene to the wider environment, that is life. It is a kind of music. Including stories from Noble's own research experience, his work on the heartbeat, musical metaphors, and elements of linguistics and Chinese culture, this very personal and at times deeply lyrical book sets out the systems biology view of life.
Author : Lily E. Kay
Release : 2000
Genre : Science
Kind : eBook
Book Rating : 172/5 ( reviews)
Book Synopsis Who Wrote the Book of Life? by : Lily E. Kay
Download or read book Who Wrote the Book of Life? written by Lily E. Kay. This book was released on 2000. Available in PDF, EPUB and Kindle. Book excerpt: This is a detailed history of one of the most important and dramatic episodes in modern science, recounted from the novel vantage point of the dawn of the information age and its impact on representations of nature, heredity, and society. Drawing on archives, published sources, and interviews, the author situates work on the genetic code (1953-70) within the history of life science, the rise of communication technosciences (cybernetics, information theory, and computers), the intersection of molecular biology with cryptanalysis and linguistics, and the social history of postwar Europe and the United States. Kay draws out the historical specificity in the process by which the central biological problem of DNA-based protein synthesis came to be metaphorically represented as an information code and a writing technologyand consequently as a book of life. This molecular writing and reading is part of the cultural production of the Nuclear Age, its power amplified by the centuries-old theistic resonance of the book of life metaphor. Yet, as the author points out, these are just metaphors: analogies, not ontologies. Necessary and productive as they have been, they have their epistemological limitations. Deploying analyses of language, cryptology, and information theory, the author persuasively argues that, technically speaking, the genetic code is not a code, DNA is not a language, and the genome is not an information system (objections voiced by experts as early as the 1950s). Thus her historical reconstruction and analyses also serve as a critique of the new genomic biopower. Genomic textuality has become a fact of life, a metaphor literalized, she claims, as human genome projects promise new levels of control over life through the meta-level of information: control of the word (the DNA sequences) and its editing and rewriting. But the author shows how the humbling limits of these scriptural metaphors also pose a challenge to the textual and material mastery of the genomic book of life.
Author : Denis Noble
Release : 2012
Genre : Biological models
Kind : eBook
Book Rating : 428/5 ( reviews)
Book Synopsis The Selected Papers of Denis Noble CBE FRS by : Denis Noble
Download or read book The Selected Papers of Denis Noble CBE FRS written by Denis Noble. This book was released on 2012. Available in PDF, EPUB and Kindle. Book excerpt: This is a scientific and philosophical autobiography written around a collection of Denis Noble's most significant papers. It traces a remarkable journey from na ve reductionism to a rigorous systems approach to living systems. It is rigorous because Denis Noble was one of the first biologists to construct computer models of cells and organs of the body. His theoretical work is entirely mathematically based, with no room for ambiguity. Far from the denigration of the systems approach as holistic 'hand-waving', his work is now regarded by pharmaceutical companies and regulators as the gold standard of modelling in the development of new medication. Systems Biology is an idea in search of a definition. This book explains why this is true: it is an approach rather than a subject. Denis Noble's work is one of the clearest examples of the systems approach in practice since it reveals the nature of some of the forms of downward causation in multilevel analysis. The story will delight readers who like to see how scientific controversy is resolved, since many of the developments described in each chapter were highly controversial when they occurred.
Author : Robert Cormier
Release : 2013-03-19
Genre : Young Adult Fiction
Kind : eBook
Book Rating : 449/5 ( reviews)
Book Synopsis Tunes for Bears to Dance To by : Robert Cormier
Download or read book Tunes for Bears to Dance To written by Robert Cormier. This book was released on 2013-03-19. Available in PDF, EPUB and Kindle. Book excerpt: Money’s tight and Henry is lucky to have the job at Mr. Hairston’s grocery store. His parents are both lost in despair following the death of Henry’s older brother, and Henry is glad for the opportunity to feel like he’s helping. Saving to buy a marker for Eddie’s grave, Henry tries to ignore Mr. Hairston’s commentary about the customers. But Henry is shocked when he is told he’s being laid off. That is, unless he agrees to do one thing, one terrible thing.
