CPP, Cell-Penetrating Peptides

2019-06-03 Science

Author : Ülo Langel
Release : 2019-06-03
Genre : Science
Kind : eBook
Book Rating : 478/5 ( reviews)

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Book Synopsis CPP, Cell-Penetrating Peptides by : Ülo Langel

Download or read book CPP, Cell-Penetrating Peptides written by Ülo Langel. This book was released on 2019-06-03. Available in PDF, EPUB and Kindle. Book excerpt: In this book, a summary and update of the most important areas of CPP research are presented, whilst raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo are discussed. Therapeutic potential of CPPs and commercial developments are discussed. The monograph is written for researchers and students in the field.

Cell-Penetrating Peptides

2015-07-24 Science

Author : Ülo Langel
Release : 2015-07-24
Genre : Science
Kind : eBook
Book Rating : 057/5 ( reviews)

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Book Synopsis Cell-Penetrating Peptides by : Ülo Langel

Download or read book Cell-Penetrating Peptides written by Ülo Langel. This book was released on 2015-07-24. Available in PDF, EPUB and Kindle. Book excerpt: Divided into three parts this volume summarizes the most important areas of Cell-Penetrating Peptides (CPP) research . Part one briefly presents the historical background of CPP studies and the classifications of the available CPPs, and then summarizes the approaches for prediction of novel CPPs. Part two mainly describes the methods for studies of “naked” CPPs, that is, CPPs without conjugated cargos. Last but not least part three presents a representative and brief summary of functionality issues of CPPs, both in vitro and in vivo. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Concise and easy-to-use, Cell-Penetrating Peptides: Methods and Protocols, Second Edition hopes to raise relevant questions for further development.

Cell Penetrating Peptides

2021-11-12 Science

Author : Ülo Langel
Release : 2021-11-12
Genre : Science
Kind : eBook
Book Rating : 519/5 ( reviews)

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Book Synopsis Cell Penetrating Peptides by : Ülo Langel

Download or read book Cell Penetrating Peptides written by Ülo Langel. This book was released on 2021-11-12. Available in PDF, EPUB and Kindle. Book excerpt: This third edition summarizes the most important areas of Cell-Penetrating Peptides (CPP) research. Chapters are divided into three parts detailing the historical background of CPP, the classifications of the available CPPs, approaches for prediction of novel CPPs, methods for studies of “naked” CPPs, and a brief summary of functionality issues of CPPs, both in vitro and in vivo. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Cell Penetrating Peptides: Methods and Protocols, Third Edition aims to be a useful practical guide to researches to help further their study in this field.

Handbook of Cell-Penetrating Peptides

2006-08-15 Medical

Author : Ulo Langel
Release : 2006-08-15
Genre : Medical
Kind : eBook
Book Rating : 088/5 ( reviews)

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Book Synopsis Handbook of Cell-Penetrating Peptides by : Ulo Langel

Download or read book Handbook of Cell-Penetrating Peptides written by Ulo Langel. This book was released on 2006-08-15. Available in PDF, EPUB and Kindle. Book excerpt: Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of new information on the use of these peptides as transport systems has in fact served to confound the field. The constant internal change in the field of cell-penetrating peptides (CPPs) is due to recent research uncovering apparent ambiguities in cellular upta

Cell-Penetrating Peptides

2002-05-29 Medical

Author : Ulo Langel
Release : 2002-05-29
Genre : Medical
Kind : eBook
Book Rating : 774/5 ( reviews)

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Book Synopsis Cell-Penetrating Peptides by : Ulo Langel

Download or read book Cell-Penetrating Peptides written by Ulo Langel. This book was released on 2002-05-29. Available in PDF, EPUB and Kindle. Book excerpt: One of the major problems with drug delivery is the inability of large hydrophilic compounds to pass through the lipid membrane of the cell, thus making drugs such as polypeptides and oligonucleotides of limited therapeutic value. Until recently, the transport of such molecules into the cytoplasmic and nuclear compartments of living cells seemed a

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