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Controlled Release in Oral Drug Delivery

2011-09-22 Medical
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Release : 2011-09-22
Genre : Medical
Kind : eBook
Book Rating : 045/5 ( reviews)

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Book Synopsis Controlled Release in Oral Drug Delivery by : Clive G. Wilson

Download or read book Controlled Release in Oral Drug Delivery written by Clive G. Wilson. This book was released on 2011-09-22. Available in PDF, EPUB and Kindle. Book excerpt: Controlled Release in Oral Drug Delivery provides focus on specific topics, complementing other books in the initial CRS series. Each chapter sets the context for the inventions described and describe the latitude that the inventions allow. In order to provide some similar look to each chapter, the coverage includes the historical overview, candidate drugs, factors influencing design and development, formulation and manufacturing and delivery system design. This volume was written along three main sections: the relevant anatomy and physiology, a discussion on candidates for oral drug delivery and the major three groups of controlled release systems: diffusion control (swelling and inert matrices); environmental control (pH sensitive coatings, time control, enzymatic control, pressure control) and finally lipidic systems.

Oral Controlled Release Formulation Design and Drug Delivery

2011-01-14 Science
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Release : 2011-01-14
Genre : Science
Kind : eBook
Book Rating : 326/5 ( reviews)

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Book Synopsis Oral Controlled Release Formulation Design and Drug Delivery by : Hong Wen

Download or read book Oral Controlled Release Formulation Design and Drug Delivery written by Hong Wen. This book was released on 2011-01-14. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.

Controlled Release in Oral Drug Delivery

2011-09-25
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Release : 2011-09-25
Genre :
Kind : eBook
Book Rating : 058/5 ( reviews)

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Book Synopsis Controlled Release in Oral Drug Delivery by :

Download or read book Controlled Release in Oral Drug Delivery written by . This book was released on 2011-09-25. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical Engineering in the Pharmaceutical Industry

2019-04-08 Technology & Engineering
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Release : 2019-04-08
Genre : Technology & Engineering
Kind : eBook
Book Rating : 50X/5 ( reviews)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : Mary T. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by Mary T. am Ende. This book was released on 2019-04-08. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.

Oral Drug Delivery for Modified Release Formulations

2022-04-04 Medical
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Release : 2022-04-04
Genre : Medical
Kind : eBook
Book Rating : 710/5 ( reviews)

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Book Synopsis Oral Drug Delivery for Modified Release Formulations by : Edmund S. Kostewicz

Download or read book Oral Drug Delivery for Modified Release Formulations written by Edmund S. Kostewicz. This book was released on 2022-04-04. Available in PDF, EPUB and Kindle. Book excerpt: ORAL DRUG DELIVERY FOR MODIFIED RELEASE FORMULATIONS Provides pharmaceutical development scientists with a detailed reference guide for the development of MR formulations Oral Drug Delivery for Modified Release Formulations is an up-to-date review of the key aspects of oral absorption from modified-release (MR) dosage forms. This edited volume provides in-depth coverage of the physiological factors that influence drug release and of the design and evaluation of MR formulations. Divided into three sections, the book begins by describing the gastrointestinal tract (GIT) and detailing the conditions and absorption processes occurring in the GIT that determine a formulation’s oral bioavailability. The second section explores the design of modified release formulations, covering early drug substance testing, the biopharmaceutics classification system, an array of formulation technologies that can be used for MR dosage forms, and more. The final section focuses on in vitro, in silico, and in vivo evaluation and regulatory considerations for MR formulations. Topics include biorelevant dissolution testing, preclinical evaluation, and physiologically-based pharmacokinetic modelling (PBPK) of in vivo behaviour. Featuring contributions from leading researchers with expertise in the different aspects of MR formulations, this volume: Provides authoritative coverage of physiology, physicochemical determinants, and in-vitro in-vivo correlation (IVIVC) Explains the different types of MR formulations and defines the key terms used in the field Discusses the present status of MR technologies and identifies current gaps in research Includes a summary of regulatory guidelines from both the US and the EU Shares industrial experiences and perspectives on the evaluation of MR dosage formulations Oral Drug Delivery for Modified Release Formulations is an invaluable reference and guide for researchers, industrial scientists, and graduate students in general areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

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