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Community Series in New Insights in Sepsis Pathogenesis and Renal Dysfunction: Immune Mechanisms and Novel Management Strategies, volume II

2023-11-17 Medical
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Release : 2023-11-17
Genre : Medical
Kind : eBook
Book Rating : 041/5 ( reviews)

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Book Synopsis Community Series in New Insights in Sepsis Pathogenesis and Renal Dysfunction: Immune Mechanisms and Novel Management Strategies, volume II by : Alessandra Stasi

Download or read book Community Series in New Insights in Sepsis Pathogenesis and Renal Dysfunction: Immune Mechanisms and Novel Management Strategies, volume II written by Alessandra Stasi. This book was released on 2023-11-17. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is the second volume of the “New Insights in Sepsis Pathogenesis and Renal Dysfunction: Immune Mechanisms and Novel Management Strategies” Community Series. Please see the first volume here. Sepsis is a systemic inflammatory response to an active infectious process in the host; the symptoms are mainly produced by host defense systems rather than by the invading pathogens, involving pro-inflammatory and anti-inflammatory processes. The association of Acute Kidney Injury (AKI) and sepsis ranges from 45% to 70% of cases, with a significantly increased risk of death, progression toward chronic kidney disease and increased health resource utilization. Despite relevant therapeutic advances, sepsis-related AKI remains associated with an unacceptably high morbidity/mortality risk, increased health resource utilization, as well as - in survivors - with increased risk of transition to chronic kidney disease. Currently there are no approved treatments for sepsis-related AKI. The main objective of this research topic is to shed new light on sepsis pathogenesis and provide new potential therapeutic strategies to prevent the progression to AKI.

New Insights in Sepsis Pathogenesis and Renal Dysfunction: Immune Mechanisms and Novel Management Strategies

2023-04-03 Medical
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Release : 2023-04-03
Genre : Medical
Kind : eBook
Book Rating : 857/5 ( reviews)

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Book Synopsis New Insights in Sepsis Pathogenesis and Renal Dysfunction: Immune Mechanisms and Novel Management Strategies by : Alessandra Stasi

Download or read book New Insights in Sepsis Pathogenesis and Renal Dysfunction: Immune Mechanisms and Novel Management Strategies written by Alessandra Stasi. This book was released on 2023-04-03. Available in PDF, EPUB and Kindle. Book excerpt:

Community series in translational insights into mechanisms and therapy of organ dysfunction in sepsis and trauma, volume II

2023-06-27 Medical
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Release : 2023-06-27
Genre : Medical
Kind : eBook
Book Rating : 608/5 ( reviews)

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Book Synopsis Community series in translational insights into mechanisms and therapy of organ dysfunction in sepsis and trauma, volume II by : Christoph Thiemermann

Download or read book Community series in translational insights into mechanisms and therapy of organ dysfunction in sepsis and trauma, volume II written by Christoph Thiemermann. This book was released on 2023-06-27. Available in PDF, EPUB and Kindle. Book excerpt:

Community Series in Translational Insights into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma, volume III

2024-07-24 Medical
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Release : 2024-07-24
Genre : Medical
Kind : eBook
Book Rating : 072/5 ( reviews)

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Book Synopsis Community Series in Translational Insights into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma, volume III by : Christoph Thiemermann

Download or read book Community Series in Translational Insights into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma, volume III written by Christoph Thiemermann. This book was released on 2024-07-24. Available in PDF, EPUB and Kindle. Book excerpt: Life-threatening organ dysfunction/failure in critically ill patients suffering from sepsis or trauma is caused by a dysregulated host response to infection and/or inflammation. Despite significant advances in our understanding of some of the key signaling pathways involved in the excessive inflammation associated with sepsis/trauma, the translation of our current understanding of the underlying pathophysiology into organ-protective therapeutic strategies is still very limited. Current therapeutic approaches, hence, continue to rely on source control, antibiotics and supportive care, and particularly early goal-directed therapy.

Sepsis Management

2011-10-11 Medical
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Release : 2011-10-11
Genre : Medical
Kind : eBook
Book Rating : 191/5 ( reviews)

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Book Synopsis Sepsis Management by : Jordi Rello

Download or read book Sepsis Management written by Jordi Rello. This book was released on 2011-10-11. Available in PDF, EPUB and Kindle. Book excerpt: This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.

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