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Clinical Applications of Metronomic Chemotherapy

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Release : 2023-12-15
Genre : Medical
Kind : eBook
Book Rating : 800/5 ( reviews)

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Book Synopsis Clinical Applications of Metronomic Chemotherapy by : Guido Bocci

Download or read book Clinical Applications of Metronomic Chemotherapy written by Guido Bocci. This book was released on 2023-12-15. Available in PDF, EPUB and Kindle. Book excerpt: Metronomic chemotherapy is now, finally, in clinical use. After 20 years of preclinical development and clinical trials, the emerging data will be of paramount importance in allowing us to assess the impact of metronomic chemotherapy on different tumor types. Indeed, it is likely that the next decade will see a major reassessment of the possible applications of metronomic chemotherapy, both alone and in combination with new therapeutic approaches such as immunotherapies, for the management of cancer. Moreover, the results of clinical trials will likely profoundly affect the direction of the laboratory efforts that are going on in parallel and aiming to improve the personalization of this therapeutic strategy. This Special Issue is our attempt to cover the past and present clinical results that have brought us to this pivotal moment and will form the basis of future clinical developments. Scientists and clinicians caring for cancer patients are well aware of the challenges in dealing with this particular therapeutic approach; one such challenge is obtaining improvements in patient survival without significant toxicity. This edition includes clinical research on chemotherapy and ongoing controversies related to metronomic chemotherapy.

Metronomic Chemotherapy

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Release : 2014-09-04
Genre : Medical
Kind : eBook
Book Rating : 043/5 ( reviews)

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Book Synopsis Metronomic Chemotherapy by : Guido Bocci

Download or read book Metronomic Chemotherapy written by Guido Bocci. This book was released on 2014-09-04. Available in PDF, EPUB and Kindle. Book excerpt: This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.

Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy

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Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 972/5 ( reviews)

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Book Synopsis Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy by : C. Julian Rosenthal

Download or read book Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy written by C. Julian Rosenthal. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: The first conference on concomitant infusion chemotherapy and radia tion therapy was organized with the intention of bringing together some of the investigators who have tested, during the last few years, the hypo thesis that continuous infusion chemotherapy could modulate the cytotoxic effect of radiation therapy to the point of having a strongly additive, if not synergistic activity on certain malignant tumors. This volume represents the detailed proceedings of this conference presented in a way that offers the reader a review of the on-going re search in the field. We have stressed a number of subjects from basic biologic research and influence of cell kinetics to the practical methods of drug delivery systems and early clinical experiences. The rationale for this new type of combined modality therapy has been presented by some of its pioneers. Early clinical investigations as well as the preliminary data of many that have not yet completely matured have also been included. The reader should look at these data with some reser vations. Ultimately, these results must be confirmed by larger prospective randomized studies with proper controls before becoming accepted as the treatment of choice in locally advanced tumors.

Novel Approaches in Metronomic Chemotherapy for Breast Cancer Treatment

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Release : 2024-05-28
Genre : Medical
Kind : eBook
Book Rating : 716/5 ( reviews)

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Book Synopsis Novel Approaches in Metronomic Chemotherapy for Breast Cancer Treatment by : Manzoor Ahmad Mir

Download or read book Novel Approaches in Metronomic Chemotherapy for Breast Cancer Treatment written by Manzoor Ahmad Mir. This book was released on 2024-05-28. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest research and developments in the field of metronomic chemotherapy for breast cancer. It presents the principles and mechanisms of metronomic chemotherapy, preclinical and clinical studies, and the latest developments in drug delivery systems and nanoformulations. The clinical pharmacology of metronomic chemotherapy, including pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions, are also examined. Key Features: Introduces metronomics therapy in the neoadjuvant and adjuvant treatment of breast cancer Explores the potential of metronomics in terms of personalized chemotherapy Present pharmacological bases of metronomic chemotherapy Covers the latest developments in drug delivery systems, nanotechnology, and nanoformulations Discusses antiangiogenic effects and the impact of metronomics on immunity This book is useful for students, researchers, oncologists, pharmacologists, and healthcare experts interested in understanding the clinical potential of metronomic chemotherapy in breast cancer.

Cancer Chemotherapy in Clinical Practice

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Release : 2007-11-24
Genre : Medical
Kind : eBook
Book Rating : 912/5 ( reviews)

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Book Synopsis Cancer Chemotherapy in Clinical Practice by : Terrence Priestman

Download or read book Cancer Chemotherapy in Clinical Practice written by Terrence Priestman. This book was released on 2007-11-24. Available in PDF, EPUB and Kindle. Book excerpt: This excellent new book summarizes the whole range of systemic cancer therapies, explaining their mode of action and potential side-effects, as well as their clinical applications. It is divided into three sections. The first tackles the theoretical basis of cancer chemotherapy: following an historical introduction, the different treatment modalities are explained in the context of basic tumor biology. The text then moves on to the subject’s practical aspects and covers dosing and drug delivery together with an extensive discussion of possible side-effects. Finally, Priestman looks at chemotherapy in the management of cancers. The book has a consistency of style which makes a wealth of complex information both readily accessible and easily understandable.

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