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Chemistry of Metalloproteins

2014-07-22 Science
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Release : 2014-07-22
Genre : Science
Kind : eBook
Book Rating : 520/5 ( reviews)

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Book Synopsis Chemistry of Metalloproteins by : Joseph J. Stephanos

Download or read book Chemistry of Metalloproteins written by Joseph J. Stephanos. This book was released on 2014-07-22. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the full gamut of questions in metalloprotein science Formatted as a question-and-answer guide, this book examines all major families of metal binding proteins, presenting our most current understanding of their structural, physicochemical, and functional properties. Moreover, it introduces new and emerging medical applications of metalloproteins. Readers will discover both the underlying chemistry and biology of this important area of research in bioinorganic chemistry. Chemistry of Metalloproteins features a building block approach that enables readers to master the basics and then advance to more sophisticated topics. The book begins with a general introduction to bioinorganic chemistry and metalloproteins. Next, it covers: Alkali and alkaline earth cations Metalloenzymes Copper proteins Iron proteins Vitamin B12 Chlorophyll Chapters are richly illustrated to help readers fully grasp all the chemical concepts that govern the biological action of metalloproteins. In addition, each chapter ends with a list of suggested original research articles and reviews for further investigation of individual topics. Presenting our most current understanding of metalloproteins, Chemistry of Metalloproteins is recommended for students and researchers in coordination chemistry, biology, and medicine. Each volume of the Wiley Series in Protein and Peptide Science addresses a specific facet of the field, reviewing the latest findings and presenting a broad range of perspectives. The volumes in this series constitute essential reading for biochemists, biophysicists, molecular biologists, geneticists, cell biologists, and physiologists as well as researchers in drug design and development, proteomics, and molecular medicine with an interest in proteins and peptides.

Handbook of Metalloproteins, Handbook of Metalloproteins

2001 Science
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Release : 2001
Genre : Science
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Handbook of Metalloproteins, Handbook of Metalloproteins by : Albrecht Messerschmidt

Download or read book Handbook of Metalloproteins, Handbook of Metalloproteins written by Albrecht Messerschmidt. This book was released on 2001. Available in PDF, EPUB and Kindle. Book excerpt: The first two volumes of the "Handbook of Metalloproteins", published in 2001, focused on a number of metals, including iron, nickel, manganese, cobalt, copper and vanadium. Now we are delighted to present volume three which extends the wealth of knowledge and focuses on proteins found in the redox-inactive ions of zinc and calcium. (Midwest).

Metalloproteins

2015-04-23 Science
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Release : 2015-04-23
Genre : Science
Kind : eBook
Book Rating : 188/5 ( reviews)

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Book Synopsis Metalloproteins by : Art E. Cho

Download or read book Metalloproteins written by Art E. Cho. This book was released on 2015-04-23. Available in PDF, EPUB and Kindle. Book excerpt: Numerous essential biological functions involve metalloproteins; therefore, understanding metalloproteins and how to manipulate them is significant in the biological and medical fields. An examination of current research, Metalloproteins: Theory, Calculations, and Experiments explores the interplay between theory and experiment, detailing the role of theoretical modeling in the field and explaining how it aids experiments. The text also presents the current state of computational protein modeling, enabling researchers to adopt computation as an integral component of their studies. This book addresses two different aspects on metalloproteins in unison. It reviews the development of theoretical and computational methods for metalloprotein simulation with specific examples. The authors also present some of the most intriguing and important experimental results on metalloprotein systems. Although a connection can be made between these two aspects of the research, the authors do not do so explicitly. Rather, they provide the platform required to ignite further collaboration between experimentalists and theoreticians. A collection of works from top researchers in this field, the text presents diverse subjects that comprehensively reflect the current state of metalloprotein research. With these advances in structural information, theory and computation are starting to play a more significant role, particularly in identifying the reaction mechanism. The book summarizes some of the recent progress in both experiments and theory/computation showing the synergy that is now developing.

Handbook on Metalloproteins

2001-06-29 Medical
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Release : 2001-06-29
Genre : Medical
Kind : eBook
Book Rating : 82X/5 ( reviews)

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Book Synopsis Handbook on Metalloproteins by : Ivano Bertini

Download or read book Handbook on Metalloproteins written by Ivano Bertini. This book was released on 2001-06-29. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook on Metalloproteins focuses on the available structural information of proteins and their metal ion coordination spheres. It centers on the metal ions indispensable for life but also considers metal ions used as substitution probes in studies of metalloproteins. Emphasizing the structure-function relationship, the book covers the commo

Metalloprotein Active Site Assembly

2017-08-14 Science
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Release : 2017-08-14
Genre : Science
Kind : eBook
Book Rating : 857/5 ( reviews)

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Book Synopsis Metalloprotein Active Site Assembly by : Michael K. Johnson

Download or read book Metalloprotein Active Site Assembly written by Michael K. Johnson. This book was released on 2017-08-14. Available in PDF, EPUB and Kindle. Book excerpt: Summarizes the essential biosynthetic pathways for assembly of metal cofactor sites in functional metalloproteins Metalloprotein Active Site Assembly focuses on the processes that have evolved to orchestrate the assembly of metal cofactor sites in functional metalloproteins. It goes beyond the simple incorporation of single metal ions in a protein framework, and includes metal cluster assembly, metal-cofactor biosynthesis and insertion, and metal-based post-translational modifications of the protein environments that are necessary for function. Several examples of each of these areas have now been identified and studied; the current volume provides the current state-of-the-art understanding of the processes involved. An excellent companion to the earlier book in this series Metals in Cells—which discussed both the positive and negative effects of cellular interactions with metals—this comprehensive book provides a diverse sampling of what is known about metalloprotein active site assembly processes. It covers all major biological transition metal components (Mn, Fe, Co, Ni, Mo), as well as the other inorganic components, metal-binding organic cofactors (e.g., heme, siroheme, cobalamin, molybdopterin), and post-translationally modified metal binding sites that make up the patchwork of evolved biological catalytic sites. The book compares and contrasts the biosynthetic assembly of active sites involving all biological metals. This has never been done before since it is a relatively new, fast-developing area of research. Metalloprotein Active Site Assembly is an ideal text for practitioners of inorganic biochemistry who are studying the biosynthetic pathways and gene clusters involved in active site assembly, and for inorganic chemists who want to apply the concepts learned to potential synthetic pathways to active site mimics.

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